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Cat. No.: HY-138653

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Lipase Substrate

Name: Lipase Substrate
Brand: MedChemExpress
SKU: HY-138653
Price: 180.00 USD
Availability: PreOrder

(Synonyms: DGGR; 1,2-o-Dilauryl-rac-glycero-3-glutaric acid (6′-methylresorufin) ester)

Lipase Substrate (DGGR; 1,2-o-Dilauryl-rac-glycero-3-glutaric acid (6′-methylresorufin) ester) is a lipase substrate that is hydrolyzed by lipase to generate methylresorufin, and the color intensity is proportional to lipase activity. Lipase Substrate can be used in research related to lipase activity detection.

For research use only. We do not sell to patients.

CAS No.: 195833-46-6
Formula: C₄₅H₆₉NO₈
Molecular Weight:752.03

Storage:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

Lipase Substrate Chemical Structure

CAS No.: 195833-46-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vivo
Chemical Information
Purity & Documentation
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Biological Activity

Description

In Vivo

Lipase Substrate (DGGR) is a lipase detection substrate, and this study shows that its lipase activity assay is prone to elevation in dogs with Cushing's disease (hypercortisolemia), cannot distinguish dogs with hypercortisolemia from dogs with acute pancreatitis, and lacks specificity^[1].
Lipase Substrate (DGGR) can be hydrolyzed not only by canine and feline pancreatic lipase but also by hepatic lipase and lipoprotein lipase; therefore, this assay lacks specificity for pancreatic lipase^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 195833-46-6
Appearance Solid
Molecular Weight 752.03
Formula C₄₅H₆₉NO₈
Color Brown to red
SMILES

O=C(OCC(OCCCCCCCCCCCC)COCCCCCCCCCCCC)CCCC(OC1=C(C)C(OC2=CC(C=CC2=N3)=O)=C3C=C1)=O
Synonyms

DGGR; 1,2-o-Dilauryl-rac-glycero-3-glutaric acid (6′-methylresorufin) ester
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Linari G, et al. Evaluation of 1,2-O-dilauryl-rac-glycero glutaric acid-(6′-methylresorufin) ester (DGGR) and 1,2-diglyceride lipase assays in dogs with naturally occurring hypercortisolism. Journal of Veterinary Diagnostic Investigation, 2021, 33(5): 817-824.

[2]. Lim SY, et al. The 1,2-o-dilauryl-rac-glycero-3-glutaric acid-(6'-methylresorufin) ester (DGGR) lipase assay in cats and dogs is not specific for pancreatic lipase. Veterinary clinical pathology. 2020 Dec;49(4):607-613.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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