Normetanephrine-d3 hydrochloride
Based on 1 Customer Validation
Normetanephrine-d3 (hydrochloride) is the deuterium labeled Normetanephrine hydrochloride. Normetanephrine ((±)-Normetanephrine) hydrochloride is the O-methylated metabolite of norepinephrine (NE).
For research use only. We do not sell to patients.
- Purity: 99.94%
- CAS No.: 1085333-97-6
- Formula: C9H11D3ClNO3
- Molecular Weight:222.68
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1085333-97-6
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Unlabeled Cas 1011-74-1
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Appearance Solid
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Molecular Weight 222.68
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Formula C9H11D3ClNO3
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Color White to off-white
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SMILES
NC([2H])([2H])C(C1=CC(OC)=C(C=C1)O)([2H])O.Cl
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Synonyms
(±)-Normetanephrine-d3 hydrochloride; DL-Normetanephrine-d3 hydrochloride; (Rac)-Normetanephrine-d3 hydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : 100 mg/mL (449.07 mM; Need ultrasonic)
DMSO : 20.83 mg/mL (93.54 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (796 KB)
- English - EN (796 KB)
- Français - FR (796 KB)
- Deutsch - DE (796 KB)
- Norwegian - NO (796 KB)
- Español - ES (796 KB)
- Swedish - SV (796 KB)
- Italian - IT (796 KB)
- Korean - KR (796 KB)
- Portuguese - PT (796 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O | 1 mM | 4.4907 mL | 22.4537 mL | 44.9075 mL | 112.2687 mL |
| 5 mM | 0.8981 mL | 4.4907 mL | 8.9815 mL | 22.4537 mL | |
| 10 mM | 0.4491 mL | 2.2454 mL | 4.4907 mL | 11.2269 mL | |
| 15 mM | 0.2994 mL | 1.4969 mL | 2.9938 mL | 7.4846 mL | |
| 20 mM | 0.2245 mL | 1.1227 mL | 2.2454 mL | 5.6134 mL | |
| 25 mM | 0.1796 mL | 0.8981 mL | 1.7963 mL | 4.4907 mL | |
| 30 mM | 0.1497 mL | 0.7485 mL | 1.4969 mL | 3.7423 mL | |
| 40 mM | 0.1123 mL | 0.5613 mL | 1.1227 mL | 2.8067 mL | |
| 50 mM | 0.0898 mL | 0.4491 mL | 0.8981 mL | 2.2454 mL | |
| 60 mM | 0.0748 mL | 0.3742 mL | 0.7485 mL | 1.8711 mL | |
| 80 mM | 0.0561 mL | 0.2807 mL | 0.5613 mL | 1.4034 mL | |
| H2O | 100 mM | 0.0449 mL | 0.2245 mL | 0.4491 mL | 1.1227 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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