Oleoylcarnitine
Based on 1 Customer Validation
Oleoylcarnitine, the metabolite which accumulates through suppression of fatty acid β-oxidation, can enhance hepatocarcinogenesis via STAT3 activation.
For research use only. We do not sell to patients.
- Purity: 99.95%
- CAS No.: 38677-66-6
- Formula: C25H47NO4
- Molecular Weight:425.64
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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All Endogenous Metabolite Isoforms
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Biological Activity
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Human Endogenous Metabolite |
Oleoylcarnitine (AC18:1) (5, 25, 50 μM; 24, 48 hours) concentration significantly increases in the Dih10 cells with stable CPT2 knock down[1].
Oleoylcarnitine (5 μM, 24 hours) contributes directly to hepatocarcinogenesis by conferring stem cell properties to cancer cells through STAT3 activation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Dih 10 cells, HCC cells
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Concentration:5, 25, 50 µM
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Incubation Time:24, 48 hours
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Result:Enhanced the self-renewal of HCC cells through STAT3 activation.
Contributed directly to hepatocarcinogenesis.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:MUP-uPA and PIK3CA Tg mice[1].
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Dosage:
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Administration:High-fat diet (HFD) for mice
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Result:Accumulated in HCC tissues and in the serum of HFD-fed mice.
Chemical Information
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CAS No. 38677-66-6
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Appearance Solid
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Molecular Weight 425.64
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Formula C25H47NO4
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Color White to off-white
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SMILES
CCCCCCCC/C=C\CCCCCCCC(O[C@H](CC([O-])=O)C[N+](C)(C)C)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 25 mg/mL (58.74 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 2.3494 mL | 11.7470 mL | 23.4940 mL | 58.7351 mL |
| 5 mM | 0.4699 mL | 2.3494 mL | 4.6988 mL | 11.7470 mL | |
| 10 mM | 0.2349 mL | 1.1747 mL | 2.3494 mL | 5.8735 mL | |
| 15 mM | 0.1566 mL | 0.7831 mL | 1.5663 mL | 3.9157 mL | |
| 20 mM | 0.1175 mL | 0.5874 mL | 1.1747 mL | 2.9368 mL | |
| 25 mM | 0.0940 mL | 0.4699 mL | 0.9398 mL | 2.3494 mL | |
| 30 mM | 0.0783 mL | 0.3916 mL | 0.7831 mL | 1.9578 mL | |
| 40 mM | 0.0587 mL | 0.2937 mL | 0.5874 mL | 1.4684 mL | |
| 50 mM | 0.0470 mL | 0.2349 mL | 0.4699 mL | 1.1747 mL |
Oleoylcarnitine Related Classifications
HY-113261 Related Classifications
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