2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Oleoylcarnitine

Oleoylcarnitine, the metabolite which accumulates through suppression of fatty acid β-oxidation, can enhance hepatocarcinogenesis via STAT3 activation.

For research use only. We do not sell to patients.

Oleoylcarnitine Chemical Structure

Oleoylcarnitine Chemical Structure

CAS No. : 38677-66-6

Size Price Stock Quantity
1 mg USD 65 In-stock
5 mg USD 165 In-stock
10 mg   Get quote  
50 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Oleoylcarnitine Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Oleoylcarnitine, the metabolite which accumulates through suppression of fatty acid β-oxidation, can enhance hepatocarcinogenesis via STAT3 activation[1].

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

Oleoylcarnitine (AC18:1) (5, 25, 50 µM; 24, 48 hours) concentration significantly increases in the Dih10 cells with stable CPT2 knock down[1].
Oleoylcarnitine (5 µM, 24 hours) contributes directly to hepatocarcinogenesis by conferring stem cell properties to cancer cells through STAT3 activation[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Oleoylcarnitine Related Antibodies

Cell Viability Assay[1]

Cell Line: Dih 10 cells, HCC cells
Concentration: 5, 25, 50 µM
Incubation Time: 24, 48 hours
Result: Enhanced the self-renewal of HCC cells through STAT3 activation.
Contributed directly to hepatocarcinogenesis.
In Vivo

Oleoylcarnitine (AC18:1) accumulates markedly in obesity-driven HCC tissues of mice[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: MUP-uPA and PIK3CA Tg mice[1].
Dosage:
Administration: High-fat diet (HFD) for mice
Result: Accumulated in HCC tissues and in the serum of HFD-fed mice.
Molecular Weight

425.64

Formula

C25H47NO4
CAS No.
Appearance

Oil

Color

White to off-white

SMILES

CCCCCCCC/C=C\CCCCCCCC(O[C@H](CC([O-])=O)C[N+](C)(C)C)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (234.94 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3494 mL 11.7470 mL 23.4940 mL
5 mM 0.4699 mL 2.3494 mL 4.6988 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥98.0%

COA (240 KB) HNMR (279 KB) MS (68 KB) Elemental Analysis Report (98 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3494 mL 11.7470 mL 23.4940 mL 58.7351 mL
5 mM 0.4699 mL 2.3494 mL 4.6988 mL 11.7470 mL
10 mM 0.2349 mL 1.1747 mL 2.3494 mL 5.8735 mL
15 mM 0.1566 mL 0.7831 mL 1.5663 mL 3.9157 mL
20 mM 0.1175 mL 0.5874 mL 1.1747 mL 2.9368 mL
25 mM 0.0940 mL 0.4699 mL 0.9398 mL 2.3494 mL
30 mM 0.0783 mL 0.3916 mL 0.7831 mL 1.9578 mL
40 mM 0.0587 mL 0.2937 mL 0.5874 mL 1.4684 mL
50 mM 0.0470 mL 0.2349 mL 0.4699 mL 1.1747 mL
60 mM 0.0392 mL 0.1958 mL 0.3916 mL 0.9789 mL
80 mM 0.0294 mL 0.1468 mL 0.2937 mL 0.7342 mL
100 mM 0.0235 mL 0.1175 mL 0.2349 mL 0.5874 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Oleoylcarnitine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Oleoylcarnitine38677-66-6Endogenous MetaboliteHCCendogenous metaboliteCPT2STAT3Dih 10Inhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Oleoylcarnitine
Cat. No.:
HY-113261
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.