1. Metabolic Enzyme/Protease
  2. Phospholipase

1-Linoleoyl Glycerol (Synonyms: 1-Linoleoyl-rac-glycerol; 1-Monolinolein)

Cat. No.: HY-111346 Purity: >99.0%
Handling Instructions

1-Linoleoyl glycerol (1-LG) is a fatty acid glycerol that has been isolated from S. chinensis roots.

For research use only. We do not sell to patients.

1-Linoleoyl Glycerol Chemical Structure

1-Linoleoyl Glycerol Chemical Structure

CAS No. : 2277-28-3

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 66 In-stock
Estimated Time of Arrival: December 31
100 mg USD 60 In-stock
Estimated Time of Arrival: December 31
500 mg USD 180 In-stock
Estimated Time of Arrival: December 31
1 g   Get quote  
5 g   Get quote  

* Please select Quantity before adding items.

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

1-Linoleoyl glycerol (1-LG) is a fatty acid glycerol that has been isolated from S. chinensis roots.

IC50 & Target

The (R)-1-Linoleoyl Glycerol and (S)-1-Linoleoyl Glycerol exhibit Lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitory activities with IC50 values of 45.0 and 52.0 μM, respectively[1].

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (282.07 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8207 mL 14.1036 mL 28.2072 mL
5 mM 0.5641 mL 2.8207 mL 5.6414 mL
10 mM 0.2821 mL 1.4104 mL 2.8207 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (7.05 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (7.05 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (7.05 mM); Clear solution

References
Molecular Weight

354.52

Formula

C₂₁H₃₈O₄

CAS No.

2277-28-3

SMILES

CCCCC/C=C\C/C=C\CCCCCCCC(OCC(O)CO)=O

Storage
Pure form -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Purity: >99.0%

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
1-Linoleoyl Glycerol
Cat. No.:
HY-111346
Quantity:

1-Linoleoyl Glycerol

Cat. No.: HY-111346