Glycerophosphoinositol 4-phosphate disodium
Glycerophosphoinositol 4-phosphate (GroPIns-4-P) disodium is a metabolite of phospholipase A and an inhibitor of adenylylcyclase. Glycerophosphoinositol 4-phosphate disodium can regulate cAMP-dependent cellular functions. Glycerophosphoinositol 4-phosphate disodium can also induce the formation of membrane ruffles and stress fibers in serum-starved Swiss 3T3 cells by activating the small GTPases Rac and Rho, respectively. Glycerophosphoinositol 4-phosphate disodium can be used in research on cancer cell motility and invasiveness.
For research use only. We do not sell to patients.
- Formula: C9H18Na2O14P2
- Molecular Weight:458.16
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Chemical Information
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Molecular Weight 458.16
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Formula C9H18Na2O14P2
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SMILES
O[C@@H]1[C@H]([C@@H]([C@H]([C@@H]([C@@H]1O)OP(OC[C@@H](CO)O)(O[Na])=O)O)O)OP(O)(O[Na])=O
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Synonyms
GroPIns-4-P disodium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Iacovelli L, et al. Glycerophosphoinositol 4-phosphate, a putative endogenous inhibitor of adenylylcyclase. J Biol Chem. 1993 Sep 25;268(27):20402-7. [Content Brief]
[2]. Mancini R, et al. Reorganization of actin cytoskeleton by the phosphoinositide metabolite glycerophosphoinositol 4-phosphate. Mol Biol Cell. 2003 Feb;14(2):503-15. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)