2. GPCR/G Protein MAPK/ERK Pathway
  3. Ras
  4. Rac1-IN-3

Rac1-IN-3 (Compound 2) is a Rac1 inhibitor with an IC50 of 46.1 μM.

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Rac1-IN-3 Chemical Structure

Rac1-IN-3 Chemical Structure

CAS No. : 380470-06-4

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10 mg USD 220 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Rac1-IN-3 (Compound 2) is a Rac1 inhibitor with an IC50 of 46.1 μM[1].

IC50 & Target

IC50: 46.1 μM (Rac1)[1]
Molecular Weight

405.45

Formula

C21H23N7O2
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

N#CC1=C(N2CCN(CC2)C3=C(OC)C=CC=C3)N=C(C4=C1C=C(OC)N=C4N)N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (308.30 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4664 mL 12.3320 mL 24.6640 mL
5 mM 0.4933 mL 2.4664 mL 4.9328 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4664 mL 12.3320 mL 24.6640 mL 61.6599 mL
5 mM 0.4933 mL 2.4664 mL 4.9328 mL 12.3320 mL
10 mM 0.2466 mL 1.2332 mL 2.4664 mL 6.1660 mL
15 mM 0.1644 mL 0.8221 mL 1.6443 mL 4.1107 mL
20 mM 0.1233 mL 0.6166 mL 1.2332 mL 3.0830 mL
25 mM 0.0987 mL 0.4933 mL 0.9866 mL 2.4664 mL
30 mM 0.0822 mL 0.4111 mL 0.8221 mL 2.0553 mL
40 mM 0.0617 mL 0.3083 mL 0.6166 mL 1.5415 mL
50 mM 0.0493 mL 0.2466 mL 0.4933 mL 1.2332 mL
60 mM 0.0411 mL 0.2055 mL 0.4111 mL 1.0277 mL
80 mM 0.0308 mL 0.1541 mL 0.3083 mL 0.7707 mL
100 mM 0.0247 mL 0.1233 mL 0.2466 mL 0.6166 mL
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Rac1-IN-3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Rac1-IN-3380470-06-4RasInhibitorinhibitorinhibit

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