(Rac)-AB-423
(Rac)-AB-423 (DVR-23) is an anti-HBV candidate compound with promising anti-HBV activity. (Rac)-AB-423 showed no induction of CYP1A2, CYP3A4, or CYP2B6 enzyme activity at high concentrations. (Rac)-AB-423 exhibited desirable pharmacokinetic properties, enabling good systemic exposure and high oral bioavailability. (Rac)-AB-423 achieved more than 2 log viral load reduction in the hydrodynamic injection (HDI) HBV mouse model.
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- CAS. Nr.: 422547-55-5
- Formel: C17H17F3N2O3S
- Molecular Weight:386.39
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Chemical Information
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CAS. Nr. 422547-55-5
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Molecular Weight 386.39
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Formel C17H17F3N2O3S
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SMILES
O=C(NC1=CC=C(F)C(F)=C1)C2=CC(S(=O)(NC(C)CC)=O)=CC=C2F
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Synonyms
DVR-23
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)