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Art. -Nr.: HY-100187

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(Rac)-[6]-Gingerol

(Synonyms: (±)-[6]-Gingerol)

(Rac)-[6]-Gingerol is a natural product. (Rac)-[6]-Gingerol can be isolated from rhizomes of Z. officinale. (Rac)-[6]-Gingerol shows moderate anticancer activity against lung cancer, ovarian cancer, melanoma, and colon cancer.

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CAS. Nr.: 39886-76-5
Formel: C₁₇H₂₆O₄
Molecular Weight:294.39

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (262 KB)

(Rac)-[6]-Gingerol Chemical Structure

CAS. Nr.: 39886-76-5

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Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Cellular Effect

Cell Line	Type	Value	Description	References
HCT-116	IC₅₀	45.05 μM Compound: N1	Cytotoxicity against human HCT116 cells assessed as reduction in cell viability after 48 hrs by WST1 assay Cytotoxicity against human HCT116 cells assessed as reduction in cell viability after 48 hrs by WST1 assay	[PMID: 28065501]
HEK293	EC₅₀	10.4 μM Compound: 1a, Racemic [6]-gingerol	Agonist activity at rat TRPA1 ion channel expressed in HEK293 cells assessed as calcium influx by fluo-4-Am-based fluorimetry Agonist activity at rat TRPA1 ion channel expressed in HEK293 cells assessed as calcium influx by fluo-4-Am-based fluorimetry	[PMID: 22257892]
HEK293	EC₅₀	3.3 μM Compound: 1a, Racemic [6]-gingerol	Agonist activity at human TRPV1 ion channel expressed in HEK293 cells assessed as calcium influx by fluo-4-Am-based fluorimetry Agonist activity at human TRPV1 ion channel expressed in HEK293 cells assessed as calcium influx by fluo-4-Am-based fluorimetry	[PMID: 22257892]
HEK293	IC₅₀	>100 μM Compound: 1a, Racemic [6]-gingerol	Antagonist activity at rat TRPA1 ion channel expressed in HEK293 cells assessed as inhibition of AITC-induced calcium influx incubated for 5 mins prior to AITC-induction by fluo-4-AM-based fluorimetry Antagonist activity at rat TRPA1 ion channel expressed in HEK293 cells assessed as inhibition of AITC-induced calcium influx incubated for 5 mins prior to AITC-induction by fluo-4-AM-based fluorimetry	[PMID: 22257892]
HEK293	IC₅₀	5 μM Compound: 1a, Racemic [6]-gingerol	Antagonist activity at human TRPV1 ion channel expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium influx incubated for 5 mins prior to capsicin-induction by fluo-4-AM-based fluorimetry Antagonist activity at human TRPV1 ion channel expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium influx incubated for 5 mins prior to capsicin-induction by fluo-4-AM-based fluorimetry	[PMID: 22257892]

Chemical Information

CAS. Nr. 39886-76-5
Molecular Weight 294.39
Formel C₁₇H₂₆O₄
SMILES

O=C(CCC1=CC=C(O)C(OC)=C1)CC(O)CCCCC
Synonyms

(±)-[6]-Gingerol
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (262 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Kim JS, et al. Cytotoxic components from the dried rhizomes of Zingiber officinale Roscoe. Arch Pharm Res. 2008 Apr;31(4):415-8. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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(Rac)-[6]-Gingerol

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(Rac)-[6]-Gingerol Related Classifications

HY-100187 Related Classifications