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Cat. No.: HY-117644

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L-749329

Name: L-749329
Brand: MedChemExpress
SKU: HY-117644
Availability: PreOrder

(Synonyms: (Rac)-L-754142)

L-749329 ((Rac)-L-754142) is an ET_A and ET_B receptor antagonist, with K_is of 0.062 nM and 2.25 nM for ET_A and ET_B respectively. L-749329 inhibits ET-1-stimulated signaling.

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CAS No.: 159590-37-1
Formule: C₂₈H₂₉NO₈S
Masse moléculaire:539.60

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

L-749329 Chemical Structure

CAS No.: 159590-37-1

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Description

L-749329 ((Rac)-L-754142) is an ET_A and ET_B receptor antagonist, with K_is of 0.062 nM and 2.25 nM for ET_A and ET_B respectively. L-749329 inhibits ET-1-stimulated signaling^[1].

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ET_A
ET_B

Chemical Information

CAS No. 159590-37-1
Masse moléculaire 539.60
Formule C₂₈H₂₉NO₈S
SMILES

O=C(C1=CC=C(C(CCC)=C1)OC(C2=CC=C3OCOC3=C2)C(NS(=O)(C4=CC=C(C(C)C)C=C4)=O)=O)O
Synonyms

(Rac)-L-754142
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Huckle WR, et al. Effects of L-749,329, an ET(A)/ET(B) endothelin receptor antagonist, in a porcine coronary artery injury model of vascular restenosis. Circulation. 2001 Apr 10;103(14):1899-905. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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L-749329

Voir tous les produits spécifiques à Isoform Endothelin Receptor

Activité biologique

Description

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

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