159590-37-1
159590-37-1
Chemical Structure
L-749329
Synonym(s): (Rac)-L-754142
- CAS No.: 159590-37-1
- Formula:C28H29NO8S
- Molecular Weight:539.60
IUPAC Name: 4-(1-(benzo[d][1,3]dioxol-5-yl)-2-((4-isopropylphenyl)sulfonamido)-2-oxoethoxy)-3-propylbenzoic acid
InChIKey: JPPYWKVKLSBQJM-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(C(CCC)=C1)OC(C2=CC=C3OCOC3=C2)C(NS(=O)(C4=CC=C(C(C)C)C=C4)=O)=O)O
Biological Activity: L-749329 ((Rac)-L-754142) is an ETA and ETB receptor antagonist, with Kis of 0.062 nM and 2.25 nM for ETA and ETB respectively. L-749329 inhibits ET-1-stimulated signaling[1].
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L-749329 | L-749329 ((Rac)-L-754142) is an ETA and ETB receptor antagonist, with Kis of 0.062 nM and 2.25 nM for ETA and ETB respectively. L-749329 inhibits ET-1-stimulated signaling. | |||||||||||||||||||||
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References
Keywords
