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Results for "

fluorescent+probes

" in MedChemExpress (MCE) Product Catalog:

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By Research Areas:	Cancer (90) Cardiovascular Disease (9) Endocrinology (1) Infection (17) Inflammation/Immunology (25) Metabolic Disease (21) Neurological Disease (37)
Click Chemistry:	Labeling and Fluorescence Imaging (9) DBCO (10) Azide (10) Tetrazine (1) Alkynes (6)
Oligonucleotides:	Fluorescent Lipids (1) Adenosine (1) Nucleoside Analogs (1) Phospholipids (2)

531

Inhibitors & Agonists

378

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

MCE Kits

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-U00451

ATP-Red 1 5+ Cited Publications	Fluorescent Dye	Others
ATP-Red 1 is a multisite-binding switchable fluorescent probe, and can selectively and rapidly responds to intracellular concentrations of ATP in living cells (Ex/Em = 510/590 nm).

HY-D0993

Acridine Orange 10-Nonyl Bromide 4 Publications Verification Nonylacridine orange	Fluorescent Dye	Others
Acridine Orange 10-Nonyl Bromide is a fluorescent probe for cardiolipin (λ_ex: 489 nm, λ_em: 525 nm).

HY-D1458

Peroxyfluor 1	Fluorescent Dye	Cardiovascular Disease Neurological Disease Cancer
Peroxyfluor 1 is a cell-permeable probe for H₂O₂. Peroxyfluor 1 represents a first-generation, green-fluorescent probe .

HY-102055

JAK2 JH2 Tracer 5+ Cited Publications	JAK	Others
JAK2 JH2 Tracer (Tracer 5) is a fluorescent probe for JAK2 JH2 domain, with a K_d value of 0.2 μM .

HY-D0133

NBD-X acid	Fluorescent Dye	Others
NBD-X acid is a fluorescent probe containing a nitrobenzoxadiazole group. NBD-X acid can be used to study the structure and function of biomolecules .

HY-133884

ICG-amine 1 Publications Verification	Fluorescent Dye	Cancer
ICG amine, as a near-infrared fluorescent probe, binds to amino acid residues without condensing agents. ICG is a tricarbocyanine dye .

HY-D1046

Dabcyl acid, SE Dabcyl, SE	Fluorescent Dye	Others
Dabcyl acid, SE is the amine-reactive form of Dabcyl acid (DABCYL) (HY-D1045), and is widely used in the preparation of fluorescent probes containing DABCYL .

HY-115691

STY-BODIPY Styrene-BODIPY; Styrene-Conjugated BODIPY	Fluorescent Dye	Others
STY-BODIPY (Styrene-BODIPY; Styrene-Conjugated BODIPY) is a styrene-conjugated fluorescent probe used to measure the activity of radical-trapping antioxidants (RTAs)> .

HY-D1459

BODIPY 665/676	Fluorescent Dye	Metabolic Disease
BODIPY 665/676 is a lipophilic radical-sensitive fluorescent probe that can be used to study radical-driven lipid autoxidation (Ex/Em=665/676 nm) .

HY-108715A

RT-AM 5+ Cited Publications	Fluorescent Dye	Neurological Disease
RT-AM is a pro-agent real thiol. Real Thiol is a reversible reaction-based fluorescent probe which can quantitatively monitor the real-time glutathione dynamics in living cells.

HY-D1719

Cypate 1 Publications Verification	Fluorescent Dye	Others
Cypate, a cyanine dye, is a near infrared (NIR) fluorescent probe for in vivo tumor imaging .

HY-D0149

4-(Trifluoromethyl)umbelliferone	Cytochrome P450	Others
4-(Trifluoromethyl)umbelliferone is fluorescent probe substrate for rat hepatic cytochrome P450 enzymes .

HY-D1837

*Vari Fluor* 488 TSA（200×）** 2 Publications Verification VF 488 Tyramide	Fluorescent Dye	Others
Vari Fluor 488 TSA（200×） (VF 488 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .

HY-130025

HKOCl-3 2 Publications Verification	Fluorescent Dye	Others
HKOCl-3 is a highly sensitive and selective fluorescent probe for detecting hypochlorous acid.E_x: 490 nm; E_m 527 nm .

HY-108715

Real Thiol	Fluorescent Dye	Neurological Disease
Real Thiol is a reversible reaction-based fluorescent probe which can quantitatively monitor the real-time glutathione dynamics in living cells.

HY-D1903

Fura Red AM 1 Publications Verification	Fluorescent Dye	Others
Fura Red AM is a fluorescent probe that can be used to visualize Ca ²⁺ distribution in the cytoplasm of undifferentiated cells. Fura Red AM operates at an excitation wavelength of 488 nm .

HY-D0099

Fluorescein-5-thiosemicarbazide	Fluorescent Dye	Others
Fluorescein-5-thiosemicarbazide is a amine containing fluorescent probe that can be used for labeling saccharides and protein carbonyl derivatives .

HY-D2312

Mito-Rh-S	Fluorescent Dye Ferroptosis	Cancer
Mito-Rh-S is a ratiometric near-infrared (NIR) fluorescent probe that detects the fluctuation of mitochondrial HClO levels during ferroptosis in hepatocellular carcinoma (HCC) .

HY-W008048

2',3'-O-Isopropylideneadenosine	Nucleoside Antimetabolite/Analog	Others
2',3'-O-Isopropylideneadenosine is a nucleoside compound and also a Golgi-targeting moiety. 2',3'-O-Isopropylideneadenosine constitutes a furanose ribose group that undergoes cyclization at the O (2') and O (3') atoms. As a component of the fluorescent probe TPE-Ade, 2',3'-O-Isopropylideneadenosine enables specific Golgi localization for fluorescence imaging. 2',3'-O-Isopropylideneadenosine participates in the synthesis of aggregation-induced emission (AIE) fluorescent probes .

HY-W267364

Coumarin 343 C343	Fluorescent Dye	Others
Coumarin 343 (C343) is a hydrophilic fluorescent probe for the micro water pool. λem is approximately 425 nm andλem is approximately from 425 nm to 550 nm by RF-1500 .

HY-U00440

FHZ	Fluorescent Dye	Others
FHZ is a fluorescent probe.

HY-W040681

7-Dimethylaminocoumarin-4-acetic acid	Fluorescent Dye	Others
7-Dimethylaminocoumarin-4-acetic acid is a fluorescent probe .

HY-D1685

BZiPAR	Fluorescent Dye	Others
BZiPAR is a *fluorescent probe. BZiPAR also is a substrate of trypsin that becomes fluorescent* after cleavage by the protease .

HY-D1835

*Vari Fluor* 594 TSA (200×)** VF 594 Tyramide	Fluorescent Dye	Others
Vari Fluor 594 TSA (200×) (VF 594 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .

HY-D1158

HKOCl-4m	Fluorescent Dye	Inflammation/Immunology
HKOCl-4m is a selective and mitochondria-targeting rhodol-based fluorescent probe for monitoring mitochondrial hypochlorous acid (HOCl) .

HY-DY1078

Acridine Orange 10-Nonyl Bromide (solution)	Fluorescent Dye	Others
Acridine Orange 10-Nonyl Bromide (solution) is a fluorescent probe for cardiolipin (λ_ex: 489 nm, λ_em: 525 nm). Solvent and concentration: DMSO: 10 mM

HY-D1255

Sel-green	Fluorescent Dye	Cancer
Sel-green, a selective selenol fluorescent probe, is applied to quantify the Sec content in the selenoenzyme thioredoxin reductase and image endogenous Sec in live HepG2 cells .

HY-147889

BBR-BODIPY	Apoptosis Caspase Bcl-2 Family	Others
BBR-BODIPY is a *fluorescent probe* that allows screening its interaction with the targeted cells. BBR-BODIPY induces apoptosis and changes the expression of apoptosis-related proteins .

HY-157036

INSA	Fluorescent Dye	Others
INSA is a a pH-sensitive fluorescent probe. INSA can simultaneously light up mitochondria (red emission) and lysosomes (green emission) for their internal pH differences .

HY-D1151

HKOH-1 3 Publications Verification	Reactive Oxygen Species (ROS) Fluorescent Dye	Others
HKOH-1 is a highly sensitive green fluorescent probe for the specific detection of ·OH in living cells with a maximum excitation wavelength and emission wavelength of 500 nm and 520 nm, respectively .

HY-D2476

*H2S Fluorescent probe* 1**	Fluorescent Dye	Others
H2S Fluorescent probe 1 (Compound 2) is a fluorescent probe that detects hydrogen sulfide (H₂S) with almost no cytotoxicity. Upon the addition of increasing amounts of HS ^- to DMSO solution of H2S Fluorescent probe 1, a new absorption peak appears gradually at 485 nm. H2S Fluorescent probe 1, the fluorescence intensity notes at 434 nm increasing rapidly by titration of HS ^- .

HY-101937C

(±)-ANAP hydrochloride 1 Publications Verification	Fluorescent Dye	Others
(±)-ANAP hydrochloride is the unnatural amino acid analog of prodan, acts as a fluorescent probes, and enhances environmental sensitivity.

HY-D1832

*Vari Fluor* 532 TSA (200×)** VF 532 Tyramide	Fluorescent Dye	Others
Vari Fluor 532 TSA (200×) (VF 532 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .

HY-D1831

*Vari Fluor* 620 TSA (200×)** VF 620 Tyramide	Fluorescent Dye	Others
Vari Fluor 620 TSA (200×) (VF 620 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .

HY-D1833

*Vari Fluor* 680 TSA (200×)** VF 680 Tyramide	Fluorescent Dye	Others
Vari Fluor 680 TSA (200×) (VF 680 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .

HY-D1834

*Vari Fluor* 640 TSA（200×）** 1 Publications Verification VF 640 Tyramide	Fluorescent Dye	Others
Vari Fluor 640 TSA（200×） (VF 640 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .

HY-D2479

DMANI	Fluorescent Dye	Metabolic Disease
DMANI is an intramolecular charge transfer (ICT)-based mitochondria-targeted ratiometric fluorescent probe. DMANI can monitor mitochondrial peroxynitrite (ONOO ⁻) in living cells .

HY-130013

HKYellow-AM (6/12-mixture)	Fluorescent Dye	Others
HKYellow-AM (6/12-mixture) is a yellow fluorescent probe that can detect ONOO- in living cells and tissues with high selectivity and sensitivity without cytotoxicity .

HY-D2418

PS-SCOTfluor-12	Fluorescent Dye	Metabolic Disease
PS-SCOTfluor-12 (compound 10) is a fluorescent probe for imaging Lactic acid (HY-B2227) metabolism in live cells. λex/λem= 485/605 nm .

HY-135640

*TAMRA-probe* 1**	Fluorescent Dye	Others
TAMRA-probe 1 is a commonly used fluorescent probe for labeling .

HY-101937A

(±)-ANAP	Fluorescent Dye	Others
(±)-ANAP is the unnatural amino acid analog of prodan, acts as a fluorescent probes, and enhances environmental sensitivity.

HY-D1395

RH-EDA	Reactive Oxygen Species (ROS)	Others
RH-EDA is a rhodamine-based turn-on fluorescent probe for detecting hydroxyl radicals in living systems.

HY-D1470

BADAN	Fluorescent Dye	Others
BADAN (6-Bromoacetyl-2-dimethylaminonaphthalene) is a polarity-sensitive fluorescent probe .

HY-D1089

6-JOE, SE	Fluorescent Dye	Others
6-JOE, SE is an amine-reactive fluorescent probe and is suitable for postsynthetic labeling of amino-modified oligonucleotides .

HY-W009253

Lophine 2,4,5-Triphenylimidazole	Fluorescent Dye	Others
Lophine is a traditional chemiluminescent and fluorescent probe. Lophine and its derivatives are widely applied for reactive oxygen species (ROS) detection .

HY-D2377

F8	Fluorescent Dye	Others
F8 is a small molecule GPR84 fluorescent probe that can visualize and detect GPR84 protein levels at the cellular and tissue levels .

HY-D0267

Quinaldine red	Fluorescent Dye	Others
Quinaldine red is a fluorescent probe for determining the melting temperature (Tm) of proteins .

HY-W337618

7-Aminocoumarin	Fluorescent Dye	Cancer
7-Aminocoumarin is highly fluorescent, acts as an optical brightener and fluorescent probe .

HY-W127843

Mag-Indo-1 tetrapotassium salt	Fluorescent Dye	Others
Mag-Indo-1 tetrapotassium salt is a cell impermeable fluorescent probe for Mg ²⁺ detection .

HY-W015012

NBD-Hydrazine	Fluorescent Dye	Others
NBD-Hydrazine is an aldehyde- and ketone-reactive fluorescent probe. NBD-Hydrazine has excitation/emission maxima of 468/535 nm in the presence of aldehydes or ketones. NBD-Hydrazine can be used as a starting material to synthesize malondialdehyde-reactive fluorescent probes. NBD-Hydrazine is a synthetic intermediate in the synthesis of cupric and chronic ion colorimetric sensors .

Cat. No.	Product Name	Type

HY-108910

Chymotrypsin

2 Publications Verification

EC 3.4.21.1; Chymotrypsin A

Biochemical Assay Reagents

Chymotrypsin (EC 3.4.21.1; Chymotrypsin A) is an orally effective inhibitor targeting molecules such as TLR4, NF-κB, MMP-1, TNF-α, IL-1β, and IL-6. Chymotrypsin downregulates the TLR4/NF-κB signaling pathway, inhibiting the release of inflammatory factors, reducing cell infiltration and tissue damage. It also reduces the expression of tumor cell adhesion molecules (such as CD44 and CD54) and can be specifically detected by fluorescent probes (such as NBD-3). Chymotrypsin has anti-inflammatory, hepatoprotective, joint damage-reducing, liver protection against lipotoxicity, and anti-tumor metastasis functions. It can be used in research on diseases such as rheumatoid arthritis, non-alcoholic fatty liver disease, and melanoma metastasis. Chymotrypsin can be used in studies of inflammation, edema, and expectoration .

HY-W007465

4-Aminobenzyl alcohol	Biochemical Assay Reagents
4-Aminobenzyl alcohol is a self-eliminating linker. 4-Aminobenzyl alcohol can be used to synthesize the fluorescent probe MB-Van1 targeting Vanin-1 .

HY-D0896

ANS

1 Publications Verification

ANSA; 8-Anilino-1-naphthalenesulfonic acid

Biochemical Assay Reagents

ANS (8-Anilino-1-naphthalenesulfonic acid) is a competitive inhibitor targeting thyroxine binding globulin (TBG) (K_i=2.09×10 ⁶ M ^-1). ANS is used in radioimmunoassay by displacing bound triiodothyronine (T3) to improve detection sensitivity. ANS can block the protein binding site of T3 and release free T3 for antibody recognition. As a fluorescent probe, ANS can specifically bind to the hydrophobic region of proteins (such as membrane proteins) and monitor the dynamics of protein conformation through changes in fluorescent signals. It is widely used in biochemical research and antibacterial material development .

HY-W011696

Oleylamine, 80-90%

cis-1-Amino-9-octadecene, 80-90%

Biochemical Assay Reagents

Oleylamine, 80-90% (cis-1-Amino-9-octadecene, 80-90%) is a multifunctional reagent used for metal ion coordination and nanoparticle surface modification, and acts as a solvent, surfactant and reducing agent in the synthesis of metal oxide nanoparticles. Oleylamine, 80-90% regulates nanoparticle morphology, magnetization intensity and water proton relaxation rate via thiol-ene "click" reaction, and enhances the colloidal stability of nanoparticles in organic reagents. Oleylamine, 80-90% is mainly used in research and applications in fields such as nanomaterial synthesis, biomedical imaging (MRI contrast agents, fluorescent probes), cancer cell targeting and drug delivery .

HY-W250727

TNS sodium

1 Publications Verification

6-(p-Tolylamino)naphthalene-2-sulfonate sodium

Biochemical Assay Reagents

TNS (6-(p-Tolylamino) naphthalene-2-sulfonate) sodium is a fluorescent probe used to detect the conformational state of proteins. TNS sodium binds to the central hydrophobic calyx of β-lactoglobulin (β-LG) to form a 1:1 complex, which stabilizes the folded conformation of β-LG. TNS sodium shows weak fluorescent signals in aqueous solution, but its fluorescence intensity increases significantly upon binding to the hydrophobic domains of proteins, with the maximum excitation wavelength and maximum emission wavelength located at 321 nm and 446 nm, respectively .

HY-34515

3,4,7,8-Tetramethyl-1,10-phenanthroline

TMPhen; 3,4,7,8-Tetramethyl-1,10-phenanthroline

Biochemical Assay Reagents

3,4,7,8-Tetramethyl-1,10-phenanthroline (TMPhen) is an organic molecule commonly used as a ligand or catalyst. It has a wide range of applications in different fields, such as organometallic chemical reactions, electrochemical detection, and organic optoelectronic devices. Due to its excellent performance in fluorescent probes, biosensors and photocatalytic reactions, it has been widely used in research in the fields of chemistry and life sciences.

HY-W090294

Perylene

Peri-dinaphthalene (purified by sublimation)

Biochemical Assay Reagents

Perylene, which is a polycyclic aromatic hydrocarbon composed of four linearly fused benzene rings, is commonly used as a pigment and dye in a variety of applications, including printing inks, plastics, and textiles. In addition, Perylene has potential uses in solar cells as photosensitizers and as fluorescent probes in biochemistry and materials science. Perylene's rigid planar structure endows it with unique electronic and optical properties, making it a versatile and important compound in many fields of chemistry and materials science.

HY-I0259

8-Amino-2-naphthol

Biochemical Assay Reagents

8-Amino-2-naphthol is a photoactive charge transfer compounds, which can be used as fluorescent probe. 8-Amino-2-naphthol undergoes excited-state proton transfer (ESPT) to form a zwitterion under acidic conditions, where the photoacidity of its hydroxyl group is regulated by the protonation state of the amino group, enabling pH to act as an on/off switch for photoacidity. 8-Amino-2-naphthol is also utilized as chiral organocatalyst .

HY-W073013

Cobalt(II) TPP

Biochemical Assay Reagents

5,10,15,20-Tetraphenyl-21H,23H-porphine cobalt(II), commonly known as CoTPP or cobalt porphyrin, is a coordination compound. 5,10,15,20-Tetraphenyl-21H,23H-porphine cobalt(II) is widely used in various fields such as catalysis, sensing, and organic electronics because of its unique electronic and optical properties. An efficient catalyst for reactions including oxidation, reduction, and CH bond activation, moreover, it has been used as a fluorescent probe for detecting oxygen content in biological systems and as an active material in organic solar cells.

HY-59303

1H-Imidazole-5-carboxaldehyde	Biochemical Assay Reagents
1H-Imidazole-5-carboxaldehyde can be used as a chemical reagent in organic synthesis reactions. 1H-Imidazole-5-carboxaldehyde can be used to prepare other imidazole compounds, such as imidazole pyrimidine and imidazolone. 1H-Imidazole-5-carboxaldehyde can also be used as biochemical dyes and fluorescent probes.

HY-W017232

6-Methoxyquinoline

p-Quinanisole

Biochemical Assay Reagents

6-Methoxyquinoline consists of a quinoline ring system with a methoxy group attached to the sixth carbon atom. This compound occurs naturally in certain plants, such as tobacco and tea, and has been shown to have biological activities, including antioxidant, anti-inflammatory and antitumor properties. Furthermore, 6-Methoxyquinoline can be used as a building block for the synthesis of other organic compounds, especially those with potential pharmaceutical applications. Due to its ability to bind nucleic acids and proteins, it can also be used as a fluorescent probe in biochemical and biomedical research.

HY-79602

p-Toluenesulfonamide	Biochemical Assay Reagents
p-Toluenesulfonamide is an intermediate and plasticizer. p-Toluenesulfonamide is also the main degradation product of the disinfectant Chloramine-T (HY-B0959) in water. p-Toluenesulfonamide facilitates the localization of fluorescent probes to the endoplasmic reticulum .

HY-121462

Cyanine Quinoline Blue	Biochemical Assay Reagents
Cyanine is an excellent fluorescent core scaffold for constructing fluorescent probes. Covalent conjugation of Cyanine with other potent compounds can not only enhance their efficacy but also expand their application modes. Cyanine supports the development of cancer theranostic agents. Cyanine can be used in cancer research .

HY-W090065

Pyren-1-ylmethanamine hydrochloride

1-Pyrenemethylamine hydrochloride

Biochemical Assay Reagents

Pyren-1-ylmethanamine hydrochloride, Pyren-1-ylmethanamine hydrochloride is commonly used as a fluorescent probe in biochemistry and molecular biology to detect and study nucleic acids, proteins and other biomolecules, moreover, it has been used in analytical chemistry Among them, for the detection of heavy metals and other pollutants in environmental samples, the pyrene group in the molecule exhibits strong fluorescence properties, which makes it useful as a sensitive and selective detector in various applications.

HY-W127780

Rhodamine 6G perchlorate Basic Red 1 perchlorate	Biochemical Assay Reagents
Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms .

HY-D0267

Quinaldine red	Biochemical Assay Reagents
Quinaldine red is a fluorescent probe for determining the melting temperature (Tm) of proteins .

HY-D0157

ZnAF-2	Biochemical Assay Reagents
ZnAF-2, 6-iso- is a cell-impermeable compound that acts as a high-affinity Zn2 -specific fluorescent probe (Kd = 2.7 nM). It exhibits low basal fluorescence with an approximately 51-fold increase in fluorescence intensity upon stoichiometric (1:1) binding to Zn2 . Little affinity for Ca2 , Mg2 , Na or K .

HY-141618

5(6)-Carboxyrhodamine 110	Biochemical Assay Reagents
5(6)-Carboxyrhodamine 110 is an amine-reactive fluorescent probe for labeling DNA, cells and proteins (Ex/Em = 498/530 nm) .

HY-W441021

DSPE-Pyrene	Biochemical Assay Reagents
DSPE-Pyrene is a phospholipid molecule with polycyclic aromatic hydrocarbon, and can be used for drug encapsulation, such as drug loaded liposomes or nanoparticles. Pyrene is a fluorescent probe whose spectrum is sensitive to the polarity of its environment.

HY-150352

Dextran-COOH (MW 40kDa)	Biochemical Assay Reagents
Dextran-COOH is a dextran derivative with carboxyl (–COOH) functional groups introduced into the molecular chain. Dextran-COOH can be covalently coupled with a variety of bioactive molecules, drugs, small molecule ligands, fluorescent probes and other functional materials .

HY-79602R

p-Toluenesulfonamide (Standard)

Biochemical Assay Reagents

p-Toluenesulfonamide (Standard) is the analytical standard of p-Toluenesulfonamide (HY-79602). This product is intended for research and analytical applications. p-Toluenesulfonamide is an intermediate and plasticizer. p-Toluenesulfonamide is also the main degradation product of the disinfectant Chloramine-T (HY-B0959) in water. p-Toluenesulfonamide facilitates the localization of fluorescent probes to the endoplasmic reticulum .

HY-150352C

Dextran-COOH (MW 100 kDa)	Biochemical Assay Reagents
Dextran-COOH (MW 100 kDa) is a dextran derivative with carboxyl (–COOH) functional groups introduced into the molecular chain. Dextran-COOH can be covalently coupled with a variety of bioactive molecules, drugs, small molecule ligands, fluorescent probes and?other?functional?materials.

HY-150352A

Dextran-COOH (MW 10 kDa)	Biochemical Assay Reagents
Dextran-COOH (MW 10 kDa) is a dextran derivative with carboxyl (–COOH) functional groups introduced into the molecular chain. Dextran-COOH can be covalently coupled with a variety of bioactive molecules, drugs, small molecule ligands, fluorescent probes and?other?functional?materials.

HY-150352D

Dextran-COOH (MW 250 kDa)	Biochemical Assay Reagents
Dextran-COOH (MW 250 kDa) is a dextran derivative with carboxyl (–COOH) functional groups introduced into the molecular chain. Dextran-COOH can be covalently coupled with a variety of bioactive molecules, drugs, small molecule ligands, fluorescent probes and?other?functional?materials.

HY-150352E

Dextran-COOH (MW 500 kDa)	Biochemical Assay Reagents
Dextran-COOH (MW 500 kDa) is a dextran derivative with carboxyl (–COOH) functional groups introduced into the molecular chain. Dextran-COOH can be covalently coupled with a variety of bioactive molecules, drugs, small molecule ligands, fluorescent probes and?other?functional?materials.

HY-150352B

Dextran-COOH (MW 70 kDa)	Biochemical Assay Reagents
Dextran-COOH (MW 70 kDa) is a dextran derivative with carboxyl (–COOH) functional groups introduced into the molecular chain. Dextran-COOH can be covalently coupled with a variety of bioactive molecules, drugs, small molecule ligands, fluorescent probes and?other?functional?materials.

Cat. No.	Product Name	Target	Research Area

HY-P2031

Phallacidin	Arp2/3 Complex	Others
Phallacidin is a natural bicyclic heptapeptide derived from the poisonous mushroom Amanita phalloides. Phallacidin binds to filamentous actin specifically with high affinity, with a K_d of 20 nM. After binding to F-actin, Phallacidin strongly inhibits its depolymerization, stabilizes microfilament structures, and prevents their disruption by drugs such as cytochalasins. When conjugated with a fluorophore, Phallacidin serves as a specific fluorescent probe for F-actin, which is used to clearly visualize the distribution of actin in the cytoskeleton (e.g., stress fibers, cortical peripheral bands) under fluorescence microscopy .

HY-P5287

cRGDfK-thioacetyl ester	Integrin	Cancer
cRGDfK-thioacetyl ester is a bioactive polypeptide molecule. cRGDfK peptide has a selective affinity for integrins. cRGDfK peptide can modify NIR fluorescent probes for cancer targeting imaging .

HY-P10943

APO-15	Fluorescent Dye	Inflammation/Immunology Cancer
APO-15 is a phosphatidylserine-binding fluorescent probe and apoptosis imaging reagent. APO-15 exhibits high chemical stability under proteolytic and oxidative conditions, enables quantification and imaging of drug-induced apoptosis in preclinical mouse models, and is applicable to fixed tissue samples and multiple in vivo administration routes (Ex = 488 nm; Em = 525 nm). APO-15 can be used in studies related to acute lung injury and breast cancer .

HY-P2496

*Endothelin 1 (swine, human), Alexa Fluor* 488-labeled**	Endothelin Receptor Fluorescent Dye NF-κB COX Prostaglandin Receptor Apoptosis TNF Receptor Interleukin Related MMP	Cardiovascular Disease Inflammation/Immunology Cancer
Endothelin 1 (swine, human), Alexa Fluor 488-labeled is an Endothelin-1 conjugated with Alexa Fluor 488 (HY-D1304). Endothelin-1 is an endogenous vasoconstrictor and agonist of ETA/ETB receptor. Endothelin 1 (swine, human) exerts effects including promoting mitosis, angiogenesis, tumor invasion and metastasis, and inhibiting apoptosis. Endothelin 1 (swine, human) induces inflammation and oxidative stress by activating the NF-κB pathway. Endothelin 1 (swine, human), Alexa Fluor 488-labeled is specifically designed for fluorescence imaging, flow cytometry or receptor localization studies, and can be used in research related to sepsis, atherosclerosis, systemic inflammatory response syndrome, cancer and congestive heart failure .

HY-P10772

L2P4	Peptide-Drug Conjugates (PDCs) EBV	Cancer
L2P4 is a peptide-based and EBNA1 targeting fluorescent probe, which inhibits the EBNA1 homodimer formation and selectively inhibits EBV+ tumor growth. L2P4 exhibits cytotoxicity in EBV-positive C666-1 cell with LC₅₀ of 46.4 μM .

HY-P10772A

L2P4 TFA	Peptide-Drug Conjugates (PDCs) EBV	Cancer
L2P4 TFA is a peptide-based and EBNA1 targeting fluorescent probe, which inhibits the EBNA1 homodimer formation and selectively inhibits EBV+ tumor growth. L2P4 TFA exhibits cytotoxicity in EBV-positive C666-1 cell with LC₅₀ of 46.4 μM .

HY-P5287A

cRGDfK-thioacetyl ester TFA	Integrin	Cancer
cRGDfK-thioacetyl ester TFA is a bioactive polypeptide molecule. cRGDfK peptide has a selective affinity for integrins. cRGDfK peptide can modify NIR fluorescent probes for cancer targeting imaging .

HY-P11265

YQGN-7	GnRH Receptor Fluorescent Dye	Cancer
YQGN-7 is a targeted fluorescent probe for the gonadotropin-releasing hormone receptor (RnRHR). YQGN-7 exhibits high selectivity and affinity for breast cancer cells (K_D = 217.8 nM). YQGN-7 achieves precise visualization of the primary and metastatic lesions of breast cancer by targeting the highly expressed GnRHR in tumor cells. YQGN-7 can be used in the research of breast cancer breast-conserving surgery (BCS) .

HY-P4703

Hydrin 1′	Oxytocin Receptor	Others
Hydrin 1′ is found in the neurohypophysis of Xenopus. Hydrin 1′ possesses a considerable steroid-releasing activity in Xenopus adrenal gland in vitro. Hydrin 1′ targets oxytocin receptor and derives a fluorescent probe of the oxytocin receptor .

HY-P11595

TBZ-1	Fluorescent Dye	Cancer
TBZ-1 is a fluorescent probe that monitors the activity of immunoproteasome (Proteasome) (iCP) in cells. TBZ-1 undergoes fluorescence activation after being selectively cleaved by β5i, which is used for intracellular activity monitoring. TBZ-1 is applicable to cancer-related research .

HY-P11637

Mitochondrial-targeted peptide BP19	Fluorescent Dye	Neurological Disease
Mitochondrial-targeted peptide BP19 is a fluorescent probe for the selective measurement of labile iron in the mitochondriairon. Mitochondrial-targeted peptide BP19 exhibits iron-selective sensing activity with mitochondrial accumulation, reduced fluorescence in iron-loaded cells, and fluorescence reinstatement upon iron chelation. Mitochondrial-targeted peptide BP19 evaluates mitochondrial labile iron levels in cultured fibroblasts with Friedreich's ataxia .

Cat. No.	Product Name

HY-K0320

ROS Assay Kit Maximum Cited Publications 9 Publications Verification
MCE ROS Assay Kit utilizes the fluorescent probe DCFH-DA to detect ROS.

HY-KD1027

Lyso Green Kit
Lyso Green is a fluorescent probe with green fluorescence for specific labeling of lysosomes in living mammalian cells.

HY-KD1029

Mito Red Kit
Mito Red is a red-fluorescent fluorescent probe that specifically labels mitochondria in living mammalian cells.

HY-KD1030

Tubulin Deep Red Kit
Tubulin Deep Red is a fluorescent probe with red fluorescence that can specifically label microtubules in living mammalian cells.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N7131

Coumarin 6 20+ Cited Publications	Alkaloids Structural Classification Classification of Application Fields Other Diseases Umbelliferae Plants Disease Research Fields Indole Alkaloids Ambrosia hispida Source Classification	Fluorescent Dye
Coumarin 6, a fluorescent dye, is used as a fluorescent probe in a microparticle drug delivery system to conduct in vivo tracking, cell uptake, and transport mechanism studies of drug delivery systems (λ_exc=450 nm, λ_em=505 nm) .

HY-N16308

ER-Laurdan	Structural Classification Lipid	Fluorescent Dye
ER-Laurdan is a derivative of the membrane-permeable fluorescent probe Laurdan (HY-D0080) that targets the endoplasmic reticulum (ER). As a membrane fluidity reporter, ER-Laurdan specifically localizes to the ER luminal membrane, and exhibits a prominent solvatochromic response to fluidity changes caused by membrane packing and exogenous saturated fatty acid stress. ER-Laurdan shows no overlapping localization with mitochondria, enables quantitative analysis of ER membrane fluidity via generalized polarization ratio measurement, and allows automatic signal masking with the help of ER markers. With high specificity and quantitative capability, ER-Laurdan serves as an important tool for investigating metabolic disorders and associated changes in the physical properties of cell membranes .

HY-P2031

Phallacidin	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Disease Research Fields Source Classification	Arp2/3 Complex
Phallacidin is a natural bicyclic heptapeptide derived from the poisonous mushroom Amanita phalloides. Phallacidin binds to filamentous actin specifically with high affinity, with a K_d of 20 nM. After binding to F-actin, Phallacidin strongly inhibits its depolymerization, stabilizes microfilament structures, and prevents their disruption by drugs such as cytochalasins. When conjugated with a fluorophore, Phallacidin serves as a specific fluorescent probe for F-actin, which is used to clearly visualize the distribution of actin in the cytoskeleton (e.g., stress fibers, cortical peripheral bands) under fluorescence microscopy .

HY-W091541

4-Hydroxy-1H-indole-3-carbaldehyde 4-Hydroxyindole-3-carboxaldehyde	Alkaloids Monophenols Classification of Application Fields Capparis spinosa L. Other Diseases Phenols Capparidaceae Plants Disease Research Fields Indole Alkaloids Source Classification	Endogenous Metabolite
4-Hydroxy-1H-indole-3-carbaldehyde (4-Hydroxyindole-3-carboxaldehyde) is a plant metabolite. 4-Hydroxy-1H-indole-3-carbaldehyde can be isolated from Capparis spinosa L. 4-Hydroxy-1H-indole-3-carbaldehyde can be used in the synthesis of fluorescent probe. 4-Hydroxy-1H-indole-3-carbaldehyde can be used in the study of inflammation-related diseases .

HY-N15875

18:1-18:1-C11 BODIPY 505/515 TG	Structural Classification Lipid	Fluorescent Dye
18:1-18:1-C11 BODIPY 505/515 TG is a fluorescently-labeled triglyceride that can be used as a fluorescent probe (Ex/Em = 495/503 nm).

HY-N16309

Cyanine 7 free acid bromide	Lipid	Fluorescent Dye
Cyanine 7 free acid bromide is a near-infrared fluorescent probe for labelling amine groups such as those on antibodies, nucleic acids, and proteins and can be detected using a variety of fluorescence detection techniques such as microscopy and flow cytometry.

HY-N16325

Golgi-laurdan	Lipid	Fluorescent Dye
Golgi-laurdan, a derivative of Laurdan (HY-D0080), is a fluorescent probe. Golgi-Laurdanmimics the structure NBD C6 Ceramide that can be used for the study of the Golgi apparatus .

HY-N16300

Mito-laurdan bromide	Lipid	Fluorescent Dye
Mito-laurdan bromide, a derivative of Laurdan (HY-D0080), is a fluorescent probe. Mito-laurdan bromide contains a cationic triphenylphosphonium moiety, which accumulates at the inner mitochondrial membrane due to its negative membrane potential, connected via a 3 carbon linker .

HY-165424

NIR-BG2	Alkaloids Other Alkaloids Cananga odorata Plants Annonaceae Indole Alkaloids Source Classification	Fluorescent Dye Glycosidase
NIR-BG2 is a near-infrared fluorescent probe targeting senescence-associated β-galactosidase (SA-β-Gal). NIR-BG2 is activated by SA-β-Gal and undergoes hydrolysis to release electrophilic quinone methide that covalently binds to surrounding proteins for in situ labeling, with a 16-fold enhancement of fluorescence signal at 709 nm . NIR-BG2 is promising for research of vivo imaging of cellular senescence .

HY-N16306

Lyso-laurdan	Lipid	Fluorescent Dye
Lyso-laurdan, a derivative of Laurdan (HY-D0080), is a fluorescent probe. Lyso-Laurdan accumulates in the lysosome via a morpholine group that is entrapped in lysosome via protonation to its cationic form in the acidic compartment. Lyso-laurdan is localized to lysosomes, allowing for the study of lysosomal membranes .

HY-N7131R

Coumarin 6 (Standard)	Alkaloids Structural Classification Umbelliferae Plants Indole Alkaloids Ambrosia hispida Source Classification	Fluorescent Dye Reference Standards
Coumarin 6 (Standard) is the analytical standard of Coumarin 6 (HY-N7131). This product is intended for research and analytical applications. Coumarin 6, a fluorescent dye, is used as a fluorescent probe in a microparticle drug delivery system to conduct in vivo tracking, cell uptake, and transport mechanism studies of drug delivery systems (λexc=450 nm, λem=505 nm) .

HY-W091541R

4-Hydroxy-1H-indole-3-carbaldehyde (Standard) 4-Hydroxyindole-3-carboxaldehyde (Standard)	Alkaloids Structural Classification Monophenols Capparis spinosa L. Phenols Capparidaceae Plants Indole Alkaloids Source Classification	Endogenous Metabolite Reference Standards
4-Hydroxy-1H-indole-3-carbaldehyde (Standard) is the analytical standard of 4-Hydroxy-1H-indole-3-carbaldehyde (HY-W091541). This product is intended for research and analytical applications. 4-Hydroxy-1H-indole-3-carbaldehyde (4-Hydroxyindole-3-carboxaldehyde) is a plant metabolite. 4-Hydroxy-1H-indole-3-carbaldehyde can be isolated from Capparis spinosa L. 4-Hydroxy-1H-indole-3-carbaldehyde can be used in the synthesis of fluorescent probe. 4-Hydroxy-1H-indole-3-carbaldehyde can be used in the study of inflammation-related diseases .

Cat. No.	Product Name	Chemical Structure

HY-79602S1

p-Toluenesulfonamide-15N
p-Toluenesulfonamide- ¹⁵N is the ¹⁵N-labeled p-Toluenesulfonamide (HY-79602). p-Toluenesulfonamide is an intermediate and plasticizer. p-Toluenesulfonamide is also the main degradation product of the disinfectant Chloramine-T (HY-B0959) in water. p-Toluenesulfonamide facilitates the localization of fluorescent probes to the endoplasmic reticulum .

HY-W008048S

2',3'-O-Isopropylideneadenosine-13C5

2',3'-O-Isopropylideneadenosine- ¹³C₅ is the ¹³C-labeled 2',3'-O-Isopropylideneadenosine (HY-W008048). 2',3'-O-Isopropylideneadenosine is a nucleoside compound and also a Golgi-targeting moiety. 2',3'-O-Isopropylideneadenosine constitutes a furanose ribose group that undergoes cyclization at the O (2') and O (3') atoms. As a component of the fluorescent probe TPE-Ade, 2',3'-O-Isopropylideneadenosine enables specific Golgi localization for fluorescence imaging. 2',3'-O-Isopropylideneadenosine participates in the synthesis of aggregation-induced emission (AIE) fluorescent probes .

HY-B1422S

9-Aminoacridine-13C6

9-Aminoacridine-13C6 is the ¹³C-labeled 9-Aminoacridine(HY-B1422). 9-Aminoacridine, a fluorescent probe, acts as an indicator of pH for quantitative determination of transmembrane pH gradients (inside acidic). 9-Aminoacridine is an antimicrobial. 9-Aminoacridine exerts its antimicrobial activity by interacting with specific bacterial DNA and disrupting the proton motive force in K. pneumoniae. 9-Aminoacridine is a HIV-1 inhibitor and inhibits HIV LTR transcription highly dependent on the presence and location of the amino moiety. 9-Aminoacridine inhibits virus replication in HIV-1 infected cell lines. 9-Aminoacridine is used as a Rifampin (RIF; HY-B0272) adjuvant for the multidrug-resistant K. pneumoniae infections .

Cat. No.	Product Name		Classification

HY-145746

Sulfo-Cy5 azide		Labeling and Fluorescence Imaging Azide
Sulfo-Cy5 azide is a near-infrared fluorescent probe with favorable click chemistry reactivity. Sulfo-Cy5 azide enables fluorescence imaging, tissue and cellular visualization of PD-L1 in tumors, and site-specific modification of anti-PD-L1 antibodies. Sulfo-Cy5 azide has been employed for RNA labeling and imaging. Sulfo-Cy5 azide can be conjugated to targeting agents for fluorescence imaging in atherosclerosis and breast cancer models (Ex/Em = 645/670 nm) .

HY-128676

N-ε-propargyloxycarbonyl-L-lysine hydrochloride 1 Publications Verification H-L-Lys(Poc)-OH hydrochloride		Alkynes Labeling and Fluorescence Imaging
N-ε-propargyloxycarbonyl-L-lysine (H-L-Lys(Poc)-OH) hydrochloride is a lysine-based unnatural amino acid (UAA). N-ε-propargyloxycarbonyl-L-lysine is widely used for bio-conjugation of fluorescent probes in diverse organisms from E. coli to mammalian cells even in animals . N-ε-propargyloxycarbonyl-L-lysine (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-159529

DBCO-PEG4-Eosin 5-isothiocyanate DBCO-PEG4-Eosin Y		DBCO
DBCO-PEG4-Eosin 5-isothiocyanate (DBCO-PEG4-Eosin Y) is a fluorescent probe. DBCO-PEG4-Eosin 5-isothiocyanate contains a clickable functional group, DBCO, and four PEG units. DBCO-PEG4-Eosin 5-isothiocyanate can be used for various imaging detections.

HY-D1506

Fl-DIBO		Labeling and Fluorescence Imaging
Fl-DIBO (fluorogenic dibenzocyclooctyne) is a selective and high sensitivity fluorescent probe to azide compounds. Fl-DIBO can react rapidly with azide compounds to form new highly fluorescent products with a maximum emission wavelength of 469 nm and excitation wavelength of 363 nm. Fl-DIBO can be used to label diazo-tagged proteins without detectable background signal interference . Fl-DIBO is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-119323

7-Azido-4-methylcoumarin 1 Publications Verification		Labeling and Fluorescence Imaging Azide
7-Azido-4-methylcoumarin is a selective coumarin-based fluorescent probe for hydrogen sulfide (H₂S). In the presence of H₂S, the aromatic azido group of 7-Azido-4-methylcoumarin is selectively reduced to produce the fluorescently active 7-amino-4-methylcoumarin (AMC). 7-Azido-4-methylcoumarin binds to the coumarin/phenol-binding site of BSA, the aglycone-binding site of UGT1A6, and the substrate-binding site of SULT1A1, respectively. 7-Azido-4-methylcoumarin retains its fluorescent properties after covalent binding, acts as a fluorescent H₂S probe, and does not react with cysteine, homocysteine or glutathione (Ex/Em = 340/445 nm) .

HY-110128

Sulfidefluor 7-AM SF7-AM		Labeling and Fluorescence Imaging Azide
Sulfidefluor 7-AM is a stable hydrogen sulphide (H₂S) fluorescent probe . Sulfidefluor 7-AM is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-151776

Cy3 methyltetrazine TZ-Cy3		Labeling and Fluorescence Imaging Tetrazine
Cy3 methyltetrazine (TZ-Cy3) is a click chemistry reagent with methyltetrazine building blocks that is highly reactive towards cyclooctene. Cy3 methyltetrazine is also a tetrazine-modified fluorescent probe that can be used to analyze protein phosphorylation in solution and living cells .

HY-139014

N-ε-propargyloxycarbonyl-L-lysine 1 Publications Verification H-L-Lys(Poc)-OH		Labeling and Fluorescence Imaging Alkynes
N-ε-propargyloxycarbonyl-L-lysine (H-L-Lys(Poc)-OH) is a lysine-based unnatural amino acid (UAA). N-ε-propargyloxycarbonyl-L-lysine is widely used for bio-conjugation of fluorescent probes in diverse organisms from E. coli to mammalian cells even in animals . N-ε-propargyloxycarbonyl-L-lysine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-D2616

ICG PEG2000 DBCO		DBCO
ICG PEG2000 DBCO is a fluorescent probe containing Indocyanine green (ICG) (HY-D0711) dye. ICG PEG2000 DBCO contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups (Ex/Em=785/813 nm).

HY-D2617

ICG PEG5000 DBCO		DBCO
ICG PEG5000 DBCO is a fluorescent probe containing Indocyanine green (ICG) (HY-D0711) dye. ICG PEG5000 DBCO contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups (Ex/Em=785/813 nm).

HY-D1274C

Sulfo-cyanine3 azide potassium		Azide
Sulfo-cyanine3 azide potassium is an azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm). Sulfo-cyanine3 azide potassium can be used for synthesis of fused tricyclic heterocycles, producing immunostimulatory agents . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-135639

*Alkyne-probe* 1**		Labeling and Fluorescence Imaging Alkynes
Alkyne-probe 1 is usually used as a Alkyne-labeled chemical or fluorescent probe. Alkyne-probe 1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-151704

ICG-alkyne		Alkynes
ICG-alkyne is a short-wave infrared (SWIR)-emitting cyanine fluorescent probe based on alkyne-derivatized indocyanine green. ICG-alkyne can undergo click chemistry reaction to conjugate with antibody molecules via binding to the azide groups introduced into antibodies. ICG-alkyne enables SWIR fluorescent molecular imaging of breast tumors in living mice. ICG-alkyne can be used in breast cancer-related research .

HY-D1274

Sulfo-cyanine3 azide		Azide
Sulfo-cyanine3 azide is an azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm). Sulfo-cyanine3 azide can be involved in synthesis of fused tricyclic heterocycles, produces immunostimulatory agents . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-D1274A

Sulfo-cyanine3 azide sodium		Labeling and Fluorescence Imaging Azide
Sulfo-cyanine3 azide sodium a water-soluble azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm). Sulfo-cyanine3 azide sodium can be involved in synthesis of fused tricyclic heterocycles, produces immunostimulatory agents . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-162129

Antitumor agent-131		Azide
Antitumor agent-131 (Compound 2-p) is an ER fluorescent probe with an IC₅₀ value of 23 nM for HepG2 tumor cells. Antitumor agent-131 can be used as a photosensitizer for the study of cancer photodynamics .

HY-D2548

Cy5-PEG2000-DBCO		DBCO
Cy5-PEG2000-DBCO is a fluorescent probe containing Cy5 (HY-D0821) dye. Cy5-PEG2000-DBCO contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-D2549

Cy5-PEG5000-DBCO		DBCO
Cy5-PEG5000-DBCO is a fluorescent probe containing Cy5 (HY-D0821) dye. Cy5-PEG5000-DBCO contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-D2522

Cy3-PEG5000-DBCO		DBCO
Cy3-PEG5000-DBCO is a fluorescent probe containing Cy3 (HY-D0822) dye. Cy3-PEG5000-DBCO contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .

HY-D2521

Cy3-PEG2000-DBCO		DBCO
Cy3-PEG2000-DBCO is a fluorescent probe containing Cy3 (HY-D0822) dye. Cy3-PEG2000-DBCO contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .

HY-D2572

Cy5.5-PEG5000-DBCO		DBCO
Cy5.5-PEG5000-DBCO is a fluorescent probe containing Cy5.5 (HY-D0924) dye. Cy5.5-PEG5000-DBCO contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-W800698

*BP Fluor* 430 alkyne**		Alkynes
BP Fluor 430 Alkyne is a green-fluorescent alkyne-activated probe routinely used for imaging of moderate to high abundance azide-containing biomolecules. BP Fluor 430 Alkyne reacts with azides via a copper-catalyzed click reaction (CuAAC) to form a stable triazole linker. BP Fluor 430 is a bright, photostable, green-fluorescent probe optimally excited near 430 nm. This probe is water-soluble and its fluorescence is pH independent over a wide pH range.

HY-D1274B

Sulfo-cyanine3 azide TEA		Azide
Sulfo-cyanine3 azide TEA is an azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm). Sulfo-cyanine3 azide TEA can be involved in synthesis of fused tricyclic heterocycles, produces immunostimulatory agents . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-D3266

IR 650 DBCO		DBCO
IR 650 DBCO is a far-red-fluorescent probe, pH-insensitive, azide-reactive probe routinely used for imaging of azide-containing biomolecules without the need for a copper catalyst. (Ex=651nm, Em=668 nm)

HY-D3253

IR 650 azide		Azide
IR 650 azide is a near-infrared fluorescent probe. The click chemistry reaction handle of IR 650 azide is a terminal azide, which can undergo a 'copper-catalyzed alkyne-azide cycloaddition' reaction. (Ex = 633nm, Em = 647nm)

HY-D3265

IR 650 alkyne		Alkynes
IR 650 Alkyne is a near-infrared fluorescent probe. The click chemistry reaction handle of IR 650 Alkyne is a terminal alkyne, which can undergo a 'copper-catalyzed alkyne-azide cycloaddition' reaction. Ex = 651nm, Em = 668nm.

HY-D3254

IR 650 picolyl azide		Azide
IR 650 picolyl azide is a near-infrared fluorescent probe. The click chemistry reaction handle of IR 650 picolyl azide is a terminal picolyl azide, which can undergo a 'copper-catalyzed alkyne-azide cycloaddition' reaction. (Ex = 650nm, Em = 670nm)

HY-D2571

Cy5.5-PEG2000-DBCO		DBCO
Cy5.5-PEG2000-DBCO is a fluorescent probe containing Cy5.5 (HY-D0924) dye. Cy5.5-PEG2000-DBCO contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

Cat. No.	Product Name		Classification

HY-162543

18:1 Liss Rhod PE 18:1 Lissamine rhodamine PE		Phospholipids
18:1 Liss Rhod (18:1 Lissamine rhodamine) PE is a fluorescent phospholipid and fluorescent probe.18:1 Liss Rhod PE admixes into phospholipid inks for large-scale monitoring of dip-pen nanolithography-generated lithographic structures via fluorescence microscopy.18:1 Liss Rhod PE undergoes phase separation or self-quenching under certain conditions in thin lipid membrane stacks .

HY-W008048

2',3'-O-Isopropylideneadenosine		Nucleoside Analogs Adenosine
2',3'-O-Isopropylideneadenosine is a nucleoside compound and also a Golgi-targeting moiety. 2',3'-O-Isopropylideneadenosine constitutes a furanose ribose group that undergoes cyclization at the O (2') and O (3') atoms. As a component of the fluorescent probe TPE-Ade, 2',3'-O-Isopropylideneadenosine enables specific Golgi localization for fluorescence imaging. 2',3'-O-Isopropylideneadenosine participates in the synthesis of aggregation-induced emission (AIE) fluorescent probes .

HY-W441021

DSPE-Pyrene		Phospholipids
DSPE-Pyrene is a phospholipid molecule with polycyclic aromatic hydrocarbon, and can be used for drug encapsulation, such as drug loaded liposomes or nanoparticles. Pyrene is a fluorescent probe whose spectrum is sensitive to the polarity of its environment.

HY-D2525

Cy3-PEG-DMPE		Fluorescent Lipids
Cy3-PEG-DMPE is a fluorescent probe that combines Cy3 (HY-D0822) fluorescent dye, polyethylene glycol (PEG) and DMPE (HY-142983). Cy3-PEG-DMPE is widely used in biomolecule labeling, cell imaging and liposome research.

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