TOR-G4
TOR-G4 is a Fluorescent probe that binds to G-quadruplex (G4) nucleic acid structures. TOR-G4 exhibits a unique fluorescence lifetime when bound to G4 compared to other structures, enabling sensitive discrimination between G4-bound and non-G4-bound states. TOR-G4 mainly colocalizes with RNA in the cytoplasm and nucleolus. TOR-G4 can be used to investigate the roles of RNA G4 in cells. TOR-G4 shows cytotoxicity against osteosarcoma cells.
For research use only. We do not sell to patients.
- CAS No.: 3030070-69-7
- Formula: C30H30IN3OS
- Molecular Weight:607.55
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
TOR-G4 (6 h) exhibits cytotoxicity toward U2OS cells with a GI50 of 143 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3030070-69-7
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Molecular Weight 607.55
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Formula C30H30IN3OS
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SMILES
CN(C)C(C=C1)=CC=C1/C=C/C2=C/C(C3=CC=CC=C3N2C)=C\C4=[N+](C)C5=C(C=CC(OC)=C5)S4.[I-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)