Sulfane sulfur probe 4
Based on 1 Customer Validation
Sulfane sulfur probe 4 (SSP4) is a fluorescent indicator with high selectivity and sensitivity toward sulfane sulfur (including small-molecule sulfane sulfur and protein-bound sulfane sulfur), and its fluorescence is inhibited by Cu2+. Sulfane sulfur probe 4 produces a fluorescence turn-on response upon reaction with sulfane sulfur. Sulfane sulfur probe 4 can detect persulfidated proteins including papain, BSA, GAPDH, and human protein disulfide isomerase. Sulfane sulfur probe 4 enables bioimaging of exogenous and endogenous sulfane sulfur in cells.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 95.16%
- CAS 番号: 1810731-98-6
- 分子式: C34H20O7S2
- 分子量:604.65
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保管条件:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
製品説明
体外実験
SSP4 (5 μM; 20 min) is a highly sensitive and highly selective fluorescent probe targeting small-molecule sulfane sulfur in cell-free systems, with a limit of detection of 28 nM. It exhibits optimal performance under pH 6.5-8 conditions and is hardly interfered with by most biomolecules except for high concentrations of GSH and Cu2+[1].
SSP4 (5-20 μM; 20-30 min) enables sensitive detection of exogenous and endogenous sulfane sulfur in HeLa, COS-7 and HEK293T cells. No cytotoxicity is observed at the relevant concentrations, and it can distinguish differences in intracellular sulfane sulfur levels based on genetic modification[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1810731-98-6
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性状 Solid
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分子量 604.65
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分子式 C34H20O7S2
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Color White to off-white
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SMILES
O=C(C1=C(S)C=CC=C1)OC2=CC=C3C(OC4=CC(OC(C5=C(S)C=CC=C5)=O)=CC=C4C36OC(C7=C6C=CC=C7)=O)=C2
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別名
SSP4
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
体外:
DMSO : 83.33 mg/mL (137.82 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (284 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6538 mL | 8.2692 mL | 16.5385 mL | 41.3462 mL |
| 5 mM | 0.3308 mL | 1.6538 mL | 3.3077 mL | 8.2692 mL | |
| 10 mM | 0.1654 mL | 0.8269 mL | 1.6538 mL | 4.1346 mL | |
| 15 mM | 0.1103 mL | 0.5513 mL | 1.1026 mL | 2.7564 mL | |
| 20 mM | 0.0827 mL | 0.4135 mL | 0.8269 mL | 2.0673 mL | |
| 25 mM | 0.0662 mL | 0.3308 mL | 0.6615 mL | 1.6538 mL | |
| 30 mM | 0.0551 mL | 0.2756 mL | 0.5513 mL | 1.3782 mL | |
| 40 mM | 0.0413 mL | 0.2067 mL | 0.4135 mL | 1.0337 mL | |
| 50 mM | 0.0331 mL | 0.1654 mL | 0.3308 mL | 0.8269 mL | |
| 60 mM | 0.0276 mL | 0.1378 mL | 0.2756 mL | 0.6891 mL | |
| 80 mM | 0.0207 mL | 0.1034 mL | 0.2067 mL | 0.5168 mL | |
| 100 mM | 0.0165 mL | 0.0827 mL | 0.1654 mL | 0.4135 mL |
Sulfane sulfur probe 4 関連分類
HY-158779 関連分類
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