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  2. HKSOX-1m (5/6-mixture) (hydrobromide)

HKSOX-1m (5/6-mixture) (hydrobromide) 

Cat. No.: HY-D1156A Purity: 99.55%
Handling Instructions

HKSOX-1m (5/6-mixture) hydrobromide is a O2•− fluorescent probe for mitochondria-targeting, exhibiting excellent selectivity and sensitivity toward O2•− over a broad range of pH, strong oxidants, and abundant reductants found in cells.

For research use only. We do not sell to patients.

HKSOX-1m (5/6-mixture) (hydrobromide) Chemical Structure

HKSOX-1m (5/6-mixture) (hydrobromide) Chemical Structure

Size Price Stock Quantity
1 mg USD 300 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

HKSOX-1m (5/6-mixture) hydrobromide is a O2•− fluorescent probe for mitochondria-targeting, exhibiting excellent selectivity and sensitivity toward O2•− over a broad range of pH, strong oxidants, and abundant reductants found in cells[1].

In Vitro

HKSOX-1m (5/6-mixture) hydrobromide (10 μM) sensitively captures signals for basal and Antimycin A (1 μM)-stimulated mitochondrial O2•− in differentiated human THP-1 cells, at very low laser power output (1% intensity at Ex 514 nm on Zeiss LSM 510 Meta)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

1258.72

Formula

C₄₉H₃₇Br₂F₁₀N₂O₁₀PS₂

SMILES

O=C1OC(C(C2=C3F)=CC(F)=C3O[S](C(F)(F)F)(=O)=O)(C4=CC(C(N(CC5)CCN5CCCC[P+](C6=CC=CC=C6)(C7=CC=CC=C7)C8=CC=CC=C8)=O)=CC=C41)C(C(O2)=C9F)=CC(F)=C9O[S](C(F)(F)F)(=O)=O.O=C%10OC(C(C%11=C%12F)=CC(F)=C%12O[S](C(F)(F)F)(=O)=O)(C(C%10=C%13)=CC=C%13C(N(CC%14)CCN%14CCCC[P+](C%15=CC=CC=C%15)(C%16=CC=CC=C%16)C%17=CC=CC=C%17)=O)C(C(O%11)=C%18F)=CC(F)=C%18O[S](C(F)(F)F)(=O)=O.[Br-].Br.[Br-].Br

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

References
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HKSOX-1m (5/6-mixture) (hydrobromide)
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HY-D1156A
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