HKSOX-1m (5/6-mixture)
Based on 2 publication(s) in Google Scholar
HKSOX-1m (5/6-mixture) is a O2 fluorescent probe for mitochondria-targeting (Ex/Em=509/534nm; green), exhibiting excellent selectivity and sensitivity toward O2 over a broad range of pH, strong oxidants, and abundant reductants found in cells.
For research use only. We do not sell to patients.
- CAS No.: 1786411-19-5
- Formula: C49H37Cl2F10N2O10PS2
- Molecular Weight:1169.82
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) HKSOX-1m (5/6-mixture)
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Biological Activity
HKSOX-1m (5/6-mixture) (10 μM) sensitively captures signals for basal and Antimycin A (1 μM)-stimulated mitochondrial O2
in differentiated human THP-1 cells, at very low laser power output (1% intensity at Ex 514 nm on Zeiss LSM 510 Meta)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
534
509
Chemical Information
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CAS No. 1786411-19-5
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Molecular Weight 1169.82
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Formula C49H37Cl2F10N2O10PS2
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SMILES
O=C1OC(C(C2=C3F)=CC(F)=C3O[S](C(F)(F)F)(=O)=O)(C4=CC(C(N(CC5)CCN5CCCC[P+](C6=CC=CC=C6)(C7=CC=CC=C7)C8=CC=CC=C8)=O)=CC=C41)C(C(O2)=C9F)=CC(F)=C9O[S](C(F)(F)F)(=O)=O.O=C%10OC(C(C%11=C%12F)=CC(F)=C%12O[S](C(F)(F)F)(=O)=O)(C(C%10=C%13)=CC=C%13C(N(CC%14)CCN%14CCCC[P+](C%15=CC=CC=C%15)(C%16=CC=CC=C%16)C%17=CC=CC=C%17)=O)C(C(O%11)=C%18F)=CC(F)=C%18O[S](C(F)(F)F)(=O)=O.[Cl-].Cl.[Cl-].Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (2)
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Journal Impact Factor
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Most Recent
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Redox Biol
Redistribution of defective mitochondria-mediated dihydroorotate dehydrogenase imparts 5-fluorouracil resistance in colorectal cancer. [Abstract]2024 May 23:73:103207. PMID: 38805974 -
Adv Healthc Mater
Biomimetic Copper-Doped Nano-Aluminum Adjuvant Potentiates Therapy in Chemoresistant Acute Myeloid Leukemia. [Abstract]2026 Mar 10:e04039. PMID: 41804653
Solvent & Solubility
DMSO : 55 mg/mL (47.02 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
References
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.8548 mL | 4.2742 mL | 8.5483 mL | 21.3708 mL |
| 5 mM | 0.1710 mL | 0.8548 mL | 1.7097 mL | 4.2742 mL | |
| 10 mM | 0.0855 mL | 0.4274 mL | 0.8548 mL | 2.1371 mL | |
| 15 mM | 0.0570 mL | 0.2849 mL | 0.5699 mL | 1.4247 mL | |
| 20 mM | 0.0427 mL | 0.2137 mL | 0.4274 mL | 1.0685 mL | |
| 25 mM | 0.0342 mL | 0.1710 mL | 0.3419 mL | 0.8548 mL | |
| 30 mM | 0.0285 mL | 0.1425 mL | 0.2849 mL | 0.7124 mL | |
| 40 mM | 0.0214 mL | 0.1069 mL | 0.2137 mL | 0.5343 mL |
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