2. Immunology/Inflammation NF-κB Metabolic Enzyme/Protease Others
  3. Reactive Oxygen Species (ROS) Fluorescent Dye
  4. HKSOX-1m (5/6-mixture)

HKSOX-1m (5/6-mixture) is a O2 fluorescent probe for mitochondria-targeting (Ex/Em=509/534nm; green), exhibiting excellent selectivity and sensitivity toward O2 over a broad range of pH, strong oxidants, and abundant reductants found in cells.

For research use only. We do not sell to patients.

HKSOX-1m (5/6-mixture)

HKSOX-1m (5/6-mixture) Chemical Structure

CAS No. : 1786411-19-5

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HKSOX-1m (5/6-mixture) Related Antibodies

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Description

HKSOX-1m (5/6-mixture) is a O2 fluorescent probe for mitochondria-targeting (Ex/Em=509/534nm; green), exhibiting excellent selectivity and sensitivity toward O2 over a broad range of pH, strong oxidants, and abundant reductants found in cells[1].
In Vitro

HKSOX-1m (5/6-mixture) (10 μM) sensitively captures signals for basal and Antimycin A (1 μM)-stimulated mitochondrial O2 in differentiated human THP-1 cells, at very low laser power output (1% intensity at Ex 514 nm on Zeiss LSM 510 Meta)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

HKSOX-1m (5/6-mixture) Related Antibodies
Molecular Weight

1169.82

Formula

C49H37Cl2F10N2O10PS2
CAS No.
Emission (Em)

534
Excitation (Ex)

509
SMILES

O=C1OC(C(C2=C3F)=CC(F)=C3O[S](C(F)(F)F)(=O)=O)(C4=CC(C(N(CC5)CCN5CCCC[P+](C6=CC=CC=C6)(C7=CC=CC=C7)C8=CC=CC=C8)=O)=CC=C41)C(C(O2)=C9F)=CC(F)=C9O[S](C(F)(F)F)(=O)=O.O=C%10OC(C(C%11=C%12F)=CC(F)=C%12O[S](C(F)(F)F)(=O)=O)(C(C%10=C%13)=CC=C%13C(N(CC%14)CCN%14CCCC[P+](C%15=CC=CC=C%15)(C%16=CC=CC=C%16)C%17=CC=CC=C%17)=O)C(C(O%11)=C%18F)=CC(F)=C%18O[S](C(F)(F)F)(=O)=O.[Cl-].Cl.[Cl-].Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

DMSO : 55 mg/mL (47.02 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.8548 mL 4.2742 mL 8.5483 mL
5 mM 0.1710 mL 0.8548 mL 1.7097 mL
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Purity & Documentation
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Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.8548 mL 4.2742 mL 8.5483 mL 21.3708 mL
5 mM 0.1710 mL 0.8548 mL 1.7097 mL 4.2742 mL
10 mM 0.0855 mL 0.4274 mL 0.8548 mL 2.1371 mL
15 mM 0.0570 mL 0.2849 mL 0.5699 mL 1.4247 mL
20 mM 0.0427 mL 0.2137 mL 0.4274 mL 1.0685 mL
25 mM 0.0342 mL 0.1710 mL 0.3419 mL 0.8548 mL
30 mM 0.0285 mL 0.1425 mL 0.2849 mL 0.7124 mL
40 mM 0.0214 mL 0.1069 mL 0.2137 mL 0.5343 mL
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HKSOX-1m (5/6-mixture) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HKSOX-1m (5/6-mixture)1786411-19-5Reactive Oxygen Species (ROS)Fluorescent DyeInhibitorinhibitorinhibit

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