G-quadruplex DNA fluorescence probe 1
Based on 1 Customer Validation
G-quadruplex DNA fluorescence probe 1 (Compound E1) is a selective G-quadruplex DNA targeting fluorescent probe. G-quadruplex DNA fluorescence probe 1 can pass through membrane and enter living cells with low cytotoxicity.
For research use only. We do not sell to patients.
- Purity: 97.81%
- Formula: C27H31IN2O3
- Molecular Weight:558.45
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Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Bioactive Compound Library Max
HY-L181
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Bioactive Compound Library
HY-L001
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High-Throughput Bioactive Compound Library
HY-L205
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Cell Cycle/DNA Damage Compound Library
HY-L004
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Anti-Aging Compound Library
HY-L034
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Covalent Screening Library
HY-L036
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Heterocyclic Compound Library
HY-L138
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MCE Bioactive Compound Library
HY-L001V
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Covalent Screening Library Plus
HY-L036P
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK-293T | IC50 |
40 μM
Compound: E1
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Cytotoxicity against human 293T cells assessed as reduction in cell viability incubated for 72 hr by CCK8 assay
Cytotoxicity against human 293T cells assessed as reduction in cell viability incubated for 72 hr by CCK8 assay
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[PMID: 32773092] |
Chemical Information
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Appearance Solid
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Molecular Weight 558.45
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Formula C27H31IN2O3
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Color Light yellow to yellow
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SMILES
COCCOCCOCCN1C2=C(C3=C1C=CC(/C=C/C4=CC=CC=[N+]4C)=C3)C=CC=C2.[I-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
DMSO : ≥ 100 mg/mL (179.07 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7907 mL | 8.9534 mL | 17.9067 mL | 44.7668 mL |
| 5 mM | 0.3581 mL | 1.7907 mL | 3.5813 mL | 8.9534 mL | |
| 10 mM | 0.1791 mL | 0.8953 mL | 1.7907 mL | 4.4767 mL | |
| 15 mM | 0.1194 mL | 0.5969 mL | 1.1938 mL | 2.9845 mL | |
| 20 mM | 0.0895 mL | 0.4477 mL | 0.8953 mL | 2.2383 mL | |
| 25 mM | 0.0716 mL | 0.3581 mL | 0.7163 mL | 1.7907 mL | |
| 30 mM | 0.0597 mL | 0.2984 mL | 0.5969 mL | 1.4922 mL | |
| 40 mM | 0.0448 mL | 0.2238 mL | 0.4477 mL | 1.1192 mL | |
| 50 mM | 0.0358 mL | 0.1791 mL | 0.3581 mL | 0.8953 mL | |
| 60 mM | 0.0298 mL | 0.1492 mL | 0.2984 mL | 0.7461 mL | |
| 80 mM | 0.0224 mL | 0.1119 mL | 0.2238 mL | 0.5596 mL | |
| 100 mM | 0.0179 mL | 0.0895 mL | 0.1791 mL | 0.4477 mL |
G-quadruplex DNA fluorescence probe 1 Related Classifications
HY-147652 Related Classifications
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