2. Metabolic Enzyme/Protease
  3. Pyruvate Kinase
  4. ZY-1

ZY-1 is a control molecule of ZY-2 (HY-D1876, a PKM2 fluorescent probe). ZY-1 shows a low fluorescence emission in HeLa, a cervical cancer cell abundant in PKM2 expression.

For research use only. We do not sell to patients.

ZY-1 Chemical Structure

ZY-1 Chemical Structure

Size Price Stock Quantity
1 mg USD 182 In-stock
5 mg USD 400 In-stock
10 mg USD 641 In-stock
25 mg USD 1346 In-stock
50 mg   Get quote  
100 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

ZY-1 Related Antibodies

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Description

ZY-1 is a control molecule of ZY-2 (HY-D1876, a PKM2 fluorescent probe). ZY-1 shows a low fluorescence emission in HeLa, a cervical cancer cell abundant in PKM2 expression[1].

Molecular Weight

465.47

Formula

C23H26F3N3O4
Appearance

Solid

Color

Yellow to orange

SMILES

[O-]C(C(F)(F)F)=O.CC[N+]1=CC=C(C=C1)/C=C/C(C=C2)=CC=C2N(CC3)CCN3CC(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (214.84 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1484 mL 10.7418 mL 21.4837 mL
5 mM 0.4297 mL 2.1484 mL 4.2967 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.1484 mL 10.7418 mL 21.4837 mL 53.7092 mL
5 mM 0.4297 mL 2.1484 mL 4.2967 mL 10.7418 mL
10 mM 0.2148 mL 1.0742 mL 2.1484 mL 5.3709 mL
15 mM 0.1432 mL 0.7161 mL 1.4322 mL 3.5806 mL
20 mM 0.1074 mL 0.5371 mL 1.0742 mL 2.6855 mL
25 mM 0.0859 mL 0.4297 mL 0.8593 mL 2.1484 mL
30 mM 0.0716 mL 0.3581 mL 0.7161 mL 1.7903 mL
40 mM 0.0537 mL 0.2685 mL 0.5371 mL 1.3427 mL
50 mM 0.0430 mL 0.2148 mL 0.4297 mL 1.0742 mL
60 mM 0.0358 mL 0.1790 mL 0.3581 mL 0.8952 mL
80 mM 0.0269 mL 0.1343 mL 0.2685 mL 0.6714 mL
100 mM 0.0215 mL 0.1074 mL 0.2148 mL 0.5371 mL
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ZY-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ZY-1ZY1ZY 1Pyruvate KinaseInhibitorinhibitorinhibit

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