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Cat. No.: HY-125749

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Coumarin-30

Coumarin-30 is a coumarin-based fluorescent dye and environment-sensitive fluorescent probe (in aqueous medium, λ_ex = 430 nm, λ_em = 495 nm). Coumarin-30 serves as a dopant for organic light-emitting diodes.

For research use only. We do not sell to patients.

CAS No.: 41044-12-6
Formula: C₂₁H₂₁N₃O₂
Molecular Weight:347.41

Storage:

Store at room temperature 3 years.

In solvent -80°C, 2 years , -20°C, 1 year

Coumarin-30 Chemical Structure

CAS No.: 41044-12-6

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
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Classifications
Bioz

Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
AGS	GI₅₀	<0.41 μM Compound: 22a	Growth inhibition of human AGS cells assessed as reduction in cell viability measured after 3 days by CCK-8 assay Growth inhibition of human AGS cells assessed as reduction in cell viability measured after 3 days by CCK-8 assay	[PMID: 38283214]
AGS	GI₅₀	0.07 μM Compound: 17a	Growth inhibition of human AGS cells Growth inhibition of human AGS cells	[PMID: 31404864]
BXPC-3	GI₅₀	<0.41 μM Compound: 22a	Growth inhibition of human BXPC-3 cells assessed as reduction in cell viability measured after 3 days by CCK-8 assay Growth inhibition of human BXPC-3 cells assessed as reduction in cell viability measured after 3 days by CCK-8 assay	[PMID: 38283214]
BXPC-3	GI₅₀	0.07 μM Compound: 17a	Growth inhibition of human BxPC3 cells Growth inhibition of human BxPC3 cells	[PMID: 31404864]
HeLa	GI₅₀	<0.41 μM Compound: 22a	Growth inhibition of human HeLa cells assessed as reduction in cell viability measured after 3 days by CCK-8 assay Growth inhibition of human HeLa cells assessed as reduction in cell viability measured after 3 days by CCK-8 assay	[PMID: 38283214]
HepG2	GI₅₀	<0.41 μM Compound: 22a	Growth inhibition of human HepG2 cells assessed as reduction in cell viability measured after 3 days by CCK-8 assay Growth inhibition of human HepG2 cells assessed as reduction in cell viability measured after 3 days by CCK-8 assay	[PMID: 38283214]
HepG2	GI₅₀	0.07 μM Compound: 17a	Growth inhibition of human HepG2 cells Growth inhibition of human HepG2 cells	[PMID: 31404864]
K562	GI₅₀	<0.41 μM Compound: 22a	Growth inhibition of human K562 cells assessed as reduction in cell viability measured after 3 days by CCK-8 assay Growth inhibition of human K562 cells assessed as reduction in cell viability measured after 3 days by CCK-8 assay	[PMID: 38283214]
K562	GI₅₀	0.07 μM Compound: 17a	Growth inhibition of human K562 cells Growth inhibition of human K562 cells	[PMID: 31404864]
K562	GI₅₀	0.07 μM Compound: 2	Anticancer activity against human K562 cells assessed as cell growth inhibition measured after 3 days by CCK-8 assay Anticancer activity against human K562 cells assessed as cell growth inhibition measured after 3 days by CCK-8 assay	[PMID: 34715585]
KATO III stomach cancer cell line	GI₅₀	<0.41 μM Compound: 22a	Growth inhibition of human KATO III stomach cancer cell line assessed as reduction in cell viability measured after 3 days by CCK-8 assay Growth inhibition of human KATO III stomach cancer cell line assessed as reduction in cell viability measured after 3 days by CCK-8 assay	[PMID: 38283214]
KATO III stomach cancer cell line	GI₅₀	0.1 μM Compound: 2	Anticancer activity against human KATO III stomach cancer cell line assessed as cell growth inhibition measured after 3 days by CCK-8 assay Anticancer activity against human KATO III stomach cancer cell line assessed as cell growth inhibition measured after 3 days by CCK-8 assay	[PMID: 34715585]
MCF7	GI₅₀	<0.41 μM Compound: 22a	Growth inhibition of human MCF7 cells assessed as reduction in cell viability measured after 3 days by CCK-8 assay Growth inhibition of human MCF7 cells assessed as reduction in cell viability measured after 3 days by CCK-8 assay	[PMID: 38283214]
MCF7	GI₅₀	0.07 μM Compound: 17a	Growth inhibition of human MCF7 cells Growth inhibition of human MCF7 cells	[PMID: 31404864]
OVCAR-8	GI₅₀	<0.41 μM Compound: 22a	Growth inhibition of human OVCAR-8 cells assessed as reduction in cell viability measured after 3 days by CCK-8 assay Growth inhibition of human OVCAR-8 cells assessed as reduction in cell viability measured after 3 days by CCK-8 assay	[PMID: 38283214]
OVCAR-8	GI₅₀	0.07 μM Compound: 17a	Growth inhibition of human OVCAR8 cells Growth inhibition of human OVCAR8 cells	[PMID: 31404864]
PANC-1	GI₅₀	<0.41 μM Compound: 22a	Growth inhibition of human PANC-1 cells assessed as reduction in cell viability measured after 3 days by CCK-8 assay Growth inhibition of human PANC-1 cells assessed as reduction in cell viability measured after 3 days by CCK-8 assay	[PMID: 38283214]
PANC-1	GI₅₀	0.07 μM Compound: 17a	Growth inhibition of human PANC1 cells Growth inhibition of human PANC1 cells	[PMID: 31404864]
PANC-1	GI₅₀	0.1 μM Compound: 2	Anticancer activity against human PANC-1 cells assessed as cell growth inhibition measured after 3 days by CCK-8 assay Anticancer activity against human PANC-1 cells assessed as cell growth inhibition measured after 3 days by CCK-8 assay	[PMID: 34715585]
SK-OV-3	GI₅₀	<0.41 μM Compound: 22a	Growth inhibition of human SK-OV-3 cells assessed as reduction in cell viability measured after 3 days by CCK-8 assay Growth inhibition of human SK-OV-3 cells assessed as reduction in cell viability measured after 3 days by CCK-8 assay	[PMID: 38283214]
SK-OV-3	GI₅₀	0.07 μM Compound: 17a	Growth inhibition of human SKOV3 cells Growth inhibition of human SKOV3 cells	[PMID: 31404864]
SK-OV-3	GI₅₀	0.07 μM Compound: 2	Anticancer activity against human SK-OV-3 cells assessed as cell growth inhibition measured after 3 days by CCK-8 assay Anticancer activity against human SK-OV-3 cells assessed as cell growth inhibition measured after 3 days by CCK-8 assay	[PMID: 34715585]
SN12C	GI₅₀	<0.41 μM Compound: 22a	Growth inhibition of human SN12C cells assessed as reduction in cell viability measured after 3 days by CCK-8 assay Growth inhibition of human SN12C cells assessed as reduction in cell viability measured after 3 days by CCK-8 assay	[PMID: 38283214]
SN12C	GI₅₀	0.07 μM Compound: 17a	Growth inhibition of human SN12C cells Growth inhibition of human SN12C cells	[PMID: 31404864]
SNU1	GI₅₀	<0.41 μM Compound: 22a	Growth inhibition of human SNU1 cells assessed as reduction in cell viability measured after 3 days by CCK-8 assay Growth inhibition of human SNU1 cells assessed as reduction in cell viability measured after 3 days by CCK-8 assay	[PMID: 38283214]
SNU1	GI₅₀	0.07 μM Compound: 17a	Growth inhibition of human SNU1 cells Growth inhibition of human SNU1 cells	[PMID: 31404864]
T-24	GI₅₀	<0.41 μM Compound: 22a	Growth inhibition of human T24 cells assessed as reduction in cell viability measured after 3 days by CCK-8 assay Growth inhibition of human T24 cells assessed as reduction in cell viability measured after 3 days by CCK-8 assay	[PMID: 38283214]
T-24	GI₅₀	0.07 μM Compound: 17a	Growth inhibition of human T24 cells Growth inhibition of human T24 cells	[PMID: 31404864]
WiDr	GI₅₀	<0.41 μM Compound: 22a	Growth inhibition of human WiDr cells assessed as reduction in cell viability measured after 3 days by CCK-8 assay Growth inhibition of human WiDr cells assessed as reduction in cell viability measured after 3 days by CCK-8 assay	[PMID: 38283214]
WiDr	GI₅₀	0.07 μM Compound: 17a	Growth inhibition of human WiDr cells Growth inhibition of human WiDr cells	[PMID: 31404864]

Chemical Information

CAS No. 41044-12-6
Appearance Solid
Molecular Weight 347.41
Formula C₂₁H₂₁N₃O₂
SMILES

O=C1C(C2=NC3=CC=CC=C3N2C)=CC4=CC=C(N(CC)CC)C=C4O1
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Store at room temperature 3 years

In solvent	-80°C	2 years
	-20°C	1 year

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Das A, et al. Exploration of Self-Aggregation of Coumarin 7 and Coumarin 30 in Water: Role of β-Cyclodextrin as a Modulator. J Phys Chem B. 2021;125(49):13482-13493. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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Coumarin-30

MCE Kinase Hinge Binder Fragment Library

Biological Activity

Chemical Information

Purity & Documentation

References

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Help & FAQs

Coumarin-30 Related Classifications

HY-125749 Related Classifications