DMANI
Based on 1 Customer Validation
DMANI is an intramolecular charge transfer (ICT)-based mitochondria-targeted ratiometric fluorescent probe. DMANI can monitor mitochondrial peroxynitrite (ONOO−) in living cells.
For research use only. We do not sell to patients.
- Purity: 99.81%
- CAS No.: 2978635-30-0
- Formula: C25H27IN2
- Molecular Weight:482.40
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
In PBS buffer (10 mM, pH = 7.4), the DMANI (5 μM) displays absorption bands at around 525 and 346 nm, but the addition of 30 μM ONOO− significantly decreased the absorption, together with the appearance of a new peak at about 360 nm. In the emission spectra, a remarkably decreased fluorescence was observed at 692 nm and a new emission band at 444 nm appeared and increased rapidly in the case of DMANI with ONOO−[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2978635-30-0
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Appearance Solid
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Molecular Weight 482.40
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Formula C25H27IN2
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Color Brown to black
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SMILES
CN(C)C1=CC=C2C(C=CC(/C=C/C(C3(C)C)=[N+](C)C4=C3C=CC=C4)=C2)=C1.[I-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 100 mg/mL (207.30 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0730 mL | 10.3648 mL | 20.7297 mL | 51.8242 mL |
| 5 mM | 0.4146 mL | 2.0730 mL | 4.1459 mL | 10.3648 mL | |
| 10 mM | 0.2073 mL | 1.0365 mL | 2.0730 mL | 5.1824 mL | |
| 15 mM | 0.1382 mL | 0.6910 mL | 1.3820 mL | 3.4549 mL | |
| 20 mM | 0.1036 mL | 0.5182 mL | 1.0365 mL | 2.5912 mL | |
| 25 mM | 0.0829 mL | 0.4146 mL | 0.8292 mL | 2.0730 mL | |
| 30 mM | 0.0691 mL | 0.3455 mL | 0.6910 mL | 1.7275 mL | |
| 40 mM | 0.0518 mL | 0.2591 mL | 0.5182 mL | 1.2956 mL | |
| 50 mM | 0.0415 mL | 0.2073 mL | 0.4146 mL | 1.0365 mL | |
| 60 mM | 0.0345 mL | 0.1727 mL | 0.3455 mL | 0.8637 mL | |
| 80 mM | 0.0259 mL | 0.1296 mL | 0.2591 mL | 0.6478 mL | |
| 100 mM | 0.0207 mL | 0.1036 mL | 0.2073 mL | 0.5182 mL |
DMANI Related Classifications
HY-D2479 Related Classifications
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