CB2R probe 1
CB2R probe 1 is a safe and green CB2R (cannabinoid 2 receptor) fluorescent probe with an Ki of 130 nM. CB2R probe 1 shows low cytotoxicity in cancer cells.
For research use only. We do not sell to patients.
- CAS No.: 2634714-79-5
- Formula: C36H42N4O4
- Molecular Weight:594.74
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
cannabinoid type-2 receptors 130 nM (Ki) |
CB2R probe 1 (compound 28) (100 nM; 24 h) shows low cytotoxicity with IC50s of 1.6, 1.4, 1.4, 1.1, 2.6, 0.55, 2.0, 2.4, 2.8 nM for PANC1, U2OS, HT29, HT29-DX, U87AD, PC3, CB2R-HEK293, MCF7, MCFT-DX cells, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 2634714-79-5
-
Molecular Weight 594.74
-
Formula C36H42N4O4
-
SMILES
CN(C1=CC2=C(C(N(C2=O)CCCCCCN3C=C(C(C4=CC=CC=C43)=O)C(N[C@@]5(CC6C7)CC7CC(C6)C5)=O)=O)C=C1)C
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)