HKOCl-4m
Based on 1 Customer Validation
HKOCl-4m is a selective and mitochondria-targeting rhodol-based fluorescent probe for monitoring mitochondrial hypochlorous acid (HOCl).
For research use only. We do not sell to patients.
- Purity: 98.27%
- CAS No.: 2031170-88-2
- Formula: C63H61BrCl2N3O7P
- Molecular Weight:1153.96
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
HKOCl-4m (5 μM; 30 min) exhibits robust increase in fluorescence intensity upon addition of HOCl. HKOCl-4m has been successfully applied in detecting endogenous HOCl in RAW264.7 mouse macrophages. HKOCl-4m could be applied for monitoring the mitochondrial HOCl formation in living cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
527
490
Chemical Information
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CAS No. 2031170-88-2
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Appearance Solid
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Molecular Weight 1153.96
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Formula C63H61BrCl2N3O7P
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Color Pink to red
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SMILES
O=C1OC2(C3=CC=CC=C31)C4=CC(C(CC(C)5C)C)=C(N5CCCC(N(CC6)CCN6C(CCCC[P+](C7=CC=CC=C7)(C8=CC=CC=C8)C9=CC=CC=C9)=O)=O)C=C4OC%10=CC(OC(C=C%11Cl)=CC(Cl)=C%11O)=CC=C2%10.[Br-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 52.5 mg/mL (45.50 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.8666 mL | 4.3329 mL | 8.6658 mL | 21.6645 mL |
| 5 mM | 0.1733 mL | 0.8666 mL | 1.7332 mL | 4.3329 mL | |
| 10 mM | 0.0867 mL | 0.4333 mL | 0.8666 mL | 2.1665 mL | |
| 15 mM | 0.0578 mL | 0.2889 mL | 0.5777 mL | 1.4443 mL | |
| 20 mM | 0.0433 mL | 0.2166 mL | 0.4333 mL | 1.0832 mL | |
| 25 mM | 0.0347 mL | 0.1733 mL | 0.3466 mL | 0.8666 mL | |
| 30 mM | 0.0289 mL | 0.1444 mL | 0.2889 mL | 0.7222 mL | |
| 40 mM | 0.0217 mL | 0.1083 mL | 0.2166 mL | 0.5416 mL |