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HKOCl-4m 

Cat. No.: HY-D1158
Handling Instructions

HKOCl-4m is a selective and mitochondria-targeting rhodol-based fluorescent probe for monitoring mitochondrial hypochlorous acid (HOCl).

For research use only. We do not sell to patients.

HKOCl-4m Chemical Structure

HKOCl-4m Chemical Structure

CAS No. : 2031170-88-2

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Description

HKOCl-4m is a selective and mitochondria-targeting rhodol-based fluorescent probe for monitoring mitochondrial hypochlorous acid (HOCl)[1].

In Vitro

HKOCl-4m (5 µM; 30 min) exhibits robust increase in fluorescence intensity upon addition of HOCl. HKOCl-4m has been successfully applied in detecting endogenous HOCl in RAW264.7 mouse macrophages. HKOCl-4m could be applied for monitoring the mitochondrial HOCl formation in living cells[1].

Molecular Weight

1153.96

Formula

C₆₃H₆₁BrCl₂N₃O₇P

CAS No.

2031170-88-2

SMILES

O=C1OC2(C3=CC=CC=C31)C4=CC(C(CC(C)5C)C)=C(N5CCCC(N(CC6)CCN6C(CCCC[P+](C7=CC=CC=C7)(C8=CC=CC=C8)C9=CC=CC=C9)=O)=O)C=C4OC%10=CC(OC(C=C%11Cl)=CC(Cl)=C%11O)=CC=C2%10.[Br-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

HKOCl-4mOthersHypochlorousAcidHOClmitochondria-targetinglivingcellsInhibitorinhibitorinhibit

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