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  4. HKOCl-4m

HKOCl-4m is a selective and mitochondria-targeting rhodol-based fluorescent probe for monitoring mitochondrial hypochlorous acid (HOCl).

For research use only. We do not sell to patients.

HKOCl-4m

HKOCl-4m Chemical Structure

CAS No. : 2031170-88-2

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Solid
1 mg In-stock
5 mg In-stock
10 mg In-stock
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Customer Review

Based on 1 publication(s) in Google Scholar

HKOCl-4m Related Antibodies

Top Publications Citing Use of Products

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Description

HKOCl-4m is a selective and mitochondria-targeting rhodol-based fluorescent probe for monitoring mitochondrial hypochlorous acid (HOCl)[1].

In Vitro

HKOCl-4m (5 μM; 30 min) exhibits robust increase in fluorescence intensity upon addition of HOCl. HKOCl-4m has been successfully applied in detecting endogenous HOCl in RAW264.7 mouse macrophages. HKOCl-4m could be applied for monitoring the mitochondrial HOCl formation in living cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

HKOCl-4m Related Antibodies
Molecular Weight

1153.96

Formula

C63H61BrCl2N3O7P
CAS No.
Appearance

Solid

Color

Pink to red

Emission (Em)

527
Excitation (Ex)

490
SMILES

O=C1OC2(C3=CC=CC=C31)C4=CC(C(CC(C)5C)C)=C(N5CCCC(N(CC6)CCN6C(CCCC[P+](C7=CC=CC=C7)(C8=CC=CC=C8)C9=CC=CC=C9)=O)=O)C=C4OC%10=CC(OC(C=C%11Cl)=CC(Cl)=C%11O)=CC=C2%10.[Br-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 52.5 mg/mL (45.50 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.8666 mL 4.3329 mL 8.6658 mL
5 mM 0.1733 mL 0.8666 mL 1.7332 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.8666 mL 4.3329 mL 8.6658 mL 21.6645 mL
5 mM 0.1733 mL 0.8666 mL 1.7332 mL 4.3329 mL
10 mM 0.0867 mL 0.4333 mL 0.8666 mL 2.1665 mL
15 mM 0.0578 mL 0.2889 mL 0.5777 mL 1.4443 mL
20 mM 0.0433 mL 0.2166 mL 0.4333 mL 1.0832 mL
25 mM 0.0347 mL 0.1733 mL 0.3466 mL 0.8666 mL
30 mM 0.0289 mL 0.1444 mL 0.2889 mL 0.7222 mL
40 mM 0.0217 mL 0.1083 mL 0.2166 mL 0.5416 mL
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HKOCl-4m Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HKOCl-4m2031170-88-2Fluorescent DyeHypochlorousAcidHOClmitochondria-targetinglivingcellsInhibitorinhibitorinhibit

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