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Cat. No.: HY-151536

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meso-Benzothiazole-BODIPY 505/515

meso-Benzothiazole-BODIPY 505/515 is a boron dipyrromethenes (BODIPY) -based fluorescent probeautophagy. meso-Benzothiazole-BODIPY 505/515 can be used for the research of Alzheimer’s diseases, lysosomal storage diseases and neural degeneration diseases.

For research use only. We do not sell to patients.

CAS No.: 2922973-15-5
Formula: C₂₀H₁₈BF₂N₃S
Molecular Weight:381.25

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (275 KB)

meso-Benzothiazole-BODIPY 505/515 Chemical Structure

CAS No.: 2922973-15-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

In Vitro

Guide (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs)^[1].
Labeling of Cells:
1. Culture cells in 20 mm confocal dishes. Incubate the cells according to your normal protocol.
2. For confocal imaging, adding 5 μM meso-Benzothiazole-BODIPY 505/515 in medium, culture cells for 30 min.
3. Fluorescence detection (Ex = 488 nm; Em = 520-600 nm).

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Immunofluorescence^[1]

Cell Line:

SH-SY5Y cells
Concentration:

5 μM
Incubation Time:

30 min
Result:

Showed relatively weak fluorescence emissions in low viscous cells, but showed strong fluorescence emissions when the SH-SY5Y cells were preincubated with LPS and nystatin.

Chemical Information

CAS No. 2922973-15-5
Molecular Weight 381.25
Formula C₂₀H₁₈BF₂N₃S
SMILES

[F-][B+3]1([F-])[N]2=C(C=C(C2=C(C3=C(C=C([N-]31)C)C)C4=NC5=CC=CC=C5S4)C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (275 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wen-Jing Shi, et al. Novel Meso-Benzothiazole-Substituted BODIPY-Based AIE Fluorescent Rotor for Imaging Lysosomal Viscosity and Monitoring Autophagy. Anal Chem. 2022 Oct 12. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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