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  3. meso-Benzothiazole-BODIPY 505/515

meso-Benzothiazole-BODIPY 505/515 is a boron dipyrromethenes (BODIPY) -based fluorescent probeautophagy. meso-Benzothiazole-BODIPY 505/515 can be used for the research of Alzheimer’s diseases, lysosomal storage diseases and neural degeneration diseases.

For research use only. We do not sell to patients.

meso-Benzothiazole-BODIPY 505/515

meso-Benzothiazole-BODIPY 505/515 Chemical Structure

CAS No. : 2922973-15-5

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Description

meso-Benzothiazole-BODIPY 505/515 is a boron dipyrromethenes (BODIPY) -based fluorescent probeautophagy. meso-Benzothiazole-BODIPY 505/515 can be used for the research of Alzheimer’s diseases, lysosomal storage diseases and neural degeneration diseases[1].

In Vitro

Guide (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs)[1].
Labeling of Cells:
1. Culture cells in 20 mm confocal dishes. Incubate the cells according to your normal protocol.
2. For confocal imaging, adding 5 μM meso-Benzothiazole-BODIPY 505/515 in medium, culture cells for 30 min.
3. Fluorescence detection (Ex = 488 nm; Em = 520-600 nm).

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Immunofluorescence[1]

Cell Line: SH-SY5Y cells
Concentration: 5 μM
Incubation Time: 30 min
Result: Showed relatively weak fluorescence emissions in low viscous cells, but showed strong fluorescence emissions when the SH-SY5Y cells were preincubated with LPS and nystatin.
Molecular Weight

381.25

Formula

C20H18BF2N3S

CAS No.
SMILES

[F-][B+3]1([F-])[N]2=C(C=C(C2=C(C3=C(C=C([N-]31)C)C)C4=NC5=CC=CC=C5S4)C)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
meso-Benzothiazole-BODIPY 505/515
Cat. No.:
HY-151536
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