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  3. meso-Benzothiazole-BODIPY 505/515

meso-Benzothiazole-BODIPY 505/515 is a boron dipyrromethenes (BODIPY) -based fluorescent probeautophagy. meso-Benzothiazole-BODIPY 505/515 can be used for the research of Alzheimer’s diseases, lysosomal storage diseases and neural degeneration diseases.

For research use only. We do not sell to patients.

meso-Benzothiazole-BODIPY 505/515 Chemical Structure

meso-Benzothiazole-BODIPY 505/515 Chemical Structure

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Description

meso-Benzothiazole-BODIPY 505/515 is a boron dipyrromethenes (BODIPY) -based fluorescent probeautophagy. meso-Benzothiazole-BODIPY 505/515 can be used for the research of Alzheimer’s diseases, lysosomal storage diseases and neural degeneration diseases[1].

In Vitro

Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs)[1].
Labeling of Cells:
1. Culture cells in 20 mm confocal dishes at a density of 5× 104 cells/mL. Incubate the cells according to your normal protocol.
2. For confocal imaging, adding 5 μM meso-Benzothiazole-BODIPY 505/515 (Probe 1) in medium are used to culture the cells for 30 min.
3. Cells are excited at 488 nm and emissions were collected at 520 600 nm.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Immunofluorescence[1]

Cell Line: SH-SY5Y cells
Concentration: 5 μM
Incubation Time: 30 min
Result: Showed relatively weak fluorescence emissions in low viscous cells, but showed strong fluorescence emissions when the SH-SY5Y cells were preincubated with LPS and nystatin.
Molecular Weight

381.25

Formula

C20H18BF2N3S

SMILES

[F-][B+3]1([F-])[N]2=C(C=C(C2=C(C3=C(C=C([N-]31)C)C)C4=NC5=CC=CC=C5S4)C)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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meso-Benzothiazole-BODIPY 505/515 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
meso-Benzothiazole-BODIPY 505/515
Cat. No.:
HY-151536
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