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  3. Fluorescent Dye
  4. CQ-Lyso

CQ-Lyso is a lysosome-targeting chromenoquinoline. CQ-Lyso is a fluorescent probe for measuring the pH of lysosomes in living cells using only single wavelength excitation. CQ-Lyso can visualize the dynamic pH changes in lysosomes.

For research use only. We do not sell to patients.

CQ-Lyso Chemical Structure

CQ-Lyso Chemical Structure

CAS No. : 2089438-23-1

Size Price Stock Quantity
5 mg USD 370 In-stock
10 mg USD 590 In-stock
25 mg USD 1180 In-stock
50 mg USD 1900 In-stock
100 mg USD 3050 In-stock
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Based on 1 publication(s) in Google Scholar

CQ-Lyso Related Antibodies

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Description

CQ-Lyso is a lysosome-targeting chromenoquinoline. CQ-Lyso is a fluorescent probe for measuring the pH of lysosomes in living cells using only single wavelength excitation. CQ-Lyso can visualize the dynamic pH changes in lysosomes[1].

Molecular Weight

485.62

Formula

C30H35N3O3
CAS No.
Appearance

Solid

Color

Yellow to brown

SMILES

C1(N=C(C2=C(OC3)C(CCCN4CCC5)=C4C5=C2)C3=C6)=C6C=C(OCCCCN7CCOCC7)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMF : 100 mg/mL (205.92 mM; ultrasonic and warming and heat to 80°C)

DMSO : 100 mg/mL (205.92 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0592 mL 10.2961 mL 20.5922 mL
5 mM 0.4118 mL 2.0592 mL 4.1184 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMF / DMSO 1 mM 2.0592 mL 10.2961 mL 20.5922 mL 51.4806 mL
5 mM 0.4118 mL 2.0592 mL 4.1184 mL 10.2961 mL
10 mM 0.2059 mL 1.0296 mL 2.0592 mL 5.1481 mL
15 mM 0.1373 mL 0.6864 mL 1.3728 mL 3.4320 mL
20 mM 0.1030 mL 0.5148 mL 1.0296 mL 2.5740 mL
25 mM 0.0824 mL 0.4118 mL 0.8237 mL 2.0592 mL
30 mM 0.0686 mL 0.3432 mL 0.6864 mL 1.7160 mL
40 mM 0.0515 mL 0.2574 mL 0.5148 mL 1.2870 mL
50 mM 0.0412 mL 0.2059 mL 0.4118 mL 1.0296 mL
60 mM 0.0343 mL 0.1716 mL 0.3432 mL 0.8580 mL
80 mM 0.0257 mL 0.1287 mL 0.2574 mL 0.6435 mL
100 mM 0.0206 mL 0.1030 mL 0.2059 mL 0.5148 mL
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CQ-Lyso Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CQ-Lyso2089438-23-1Fluorescent DyeInhibitorinhibitorinhibit

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