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  3. Heptamethine cyanine dye-1

Heptamethine cyanine dye-1  (Synonyms: ADS 815EI)

Cat. No.: HY-D0921 Purity: 96.0%
Handling Instructions Technical Support

Heptamethine cyanine dye-1 (Compound CyCl) is a cyanine dye (Fmax: 858 nm, in CH2Cl2). Heptamethine cyanine dye-1 can be used to synthesize pH near-infrared fluorescent probes.

For research use only. We do not sell to patients.

Heptamethine cyanine dye-1

Heptamethine cyanine dye-1 Chemical Structure

CAS No. : 162411-29-2

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Solid
5 mg In-stock
10 mg In-stock
25 mg In-stock
50 mg In-stock
100 mg In-stock
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Heptamethine cyanine dye-1 (Compound CyCl) is a cyanine dye (Fmax: 858 nm, in CH2Cl2). Heptamethine cyanine dye-1 can be used to synthesize pH near-infrared fluorescent probes[1][2].

Molecular Weight

739.17

Formula

C42H44ClIN2

CAS No.
Appearance

Solid

Color

Light brown to black

SMILES

CC1(C)C(/C=C/C2=C(Cl)/C(CCC2)=C/C=C3N(CC)C4=C(C5=CC=CC=C5C=C4)C/3(C)C)=[N+](CC)C6=C1C7=CC=CC=C7C=C6.[I-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (67.64 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3529 mL 6.7643 mL 13.5287 mL
5 mM 0.2706 mL 1.3529 mL 2.7057 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.3529 mL 6.7643 mL 13.5287 mL 33.8217 mL
5 mM 0.2706 mL 1.3529 mL 2.7057 mL 6.7643 mL
10 mM 0.1353 mL 0.6764 mL 1.3529 mL 3.3822 mL
15 mM 0.0902 mL 0.4510 mL 0.9019 mL 2.2548 mL
20 mM 0.0676 mL 0.3382 mL 0.6764 mL 1.6911 mL
25 mM 0.0541 mL 0.2706 mL 0.5411 mL 1.3529 mL
30 mM 0.0451 mL 0.2255 mL 0.4510 mL 1.1274 mL
40 mM 0.0338 mL 0.1691 mL 0.3382 mL 0.8455 mL
50 mM 0.0271 mL 0.1353 mL 0.2706 mL 0.6764 mL
60 mM 0.0225 mL 0.1127 mL 0.2255 mL 0.5637 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Heptamethine cyanine dye-1
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