4-(Trifluoromethyl)umbelliferone
Based on 1 Customer Validation
4-(Trifluoromethyl)umbelliferone is fluorescent probe substrate for rat hepatic cytochrome P450 enzymes.
For research use only. We do not sell to patients.
- Purity: 98.69%
- CAS No.: 575-03-1
- Formula: C10H5F3O3
- Molecular Weight:230.14
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
0.19 μM
Compound: 3c
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Inhibition of human 17beta-HSD3 expressed in HeLa cells
Inhibition of human 17beta-HSD3 expressed in HeLa cells
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[PMID: 19954971] |
| SK-MEL-28 | IC50 |
1.1 μM
Compound: 10
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Anticancer activity against human SK-MEL-28 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
Anticancer activity against human SK-MEL-28 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
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[PMID: 37197457] |
| SK-MEL3 | IC50 |
0.58 μM
Compound: 10
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Anticancer activity against human SK-MEL3 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
Anticancer activity against human SK-MEL3 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
|
[PMID: 37197457] |
460
335
Chemical Information
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CAS No. 575-03-1
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Appearance Solid
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Molecular Weight 230.14
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Formula C10H5F3O3
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Color Pale purple to light pink
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SMILES
O=C1C=C(C(F)(F)F)C2=CC=C(O)C=C2O1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : ≥ 100 mg/mL (434.52 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (480 KB)
- English - EN (480 KB)
- Français - FR (480 KB)
- Deutsch - DE (480 KB)
- Norwegian - NO (480 KB)
- Español - ES (480 KB)
- Swedish - SV (480 KB)
- Italian - IT (480 KB)
- Korean - KR (480 KB)
- Portuguese - PT (480 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.3452 mL | 21.7259 mL | 43.4518 mL | 108.6295 mL |
| 5 mM | 0.8690 mL | 4.3452 mL | 8.6904 mL | 21.7259 mL | |
| 10 mM | 0.4345 mL | 2.1726 mL | 4.3452 mL | 10.8630 mL | |
| 15 mM | 0.2897 mL | 1.4484 mL | 2.8968 mL | 7.2420 mL | |
| 20 mM | 0.2173 mL | 1.0863 mL | 2.1726 mL | 5.4315 mL | |
| 25 mM | 0.1738 mL | 0.8690 mL | 1.7381 mL | 4.3452 mL | |
| 30 mM | 0.1448 mL | 0.7242 mL | 1.4484 mL | 3.6210 mL | |
| 40 mM | 0.1086 mL | 0.5431 mL | 1.0863 mL | 2.7157 mL | |
| 50 mM | 0.0869 mL | 0.4345 mL | 0.8690 mL | 2.1726 mL | |
| 60 mM | 0.0724 mL | 0.3621 mL | 0.7242 mL | 1.8105 mL | |
| 80 mM | 0.0543 mL | 0.2716 mL | 0.5431 mL | 1.3579 mL | |
| 100 mM | 0.0435 mL | 0.2173 mL | 0.4345 mL | 1.0863 mL |
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