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2-o-

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GMP Molecules

Cat. No.	Nombre del producto	Target	Áreas de investigación	Chemical Structure

HY-107543

*8-pCPT-2′-O-Me-cAMP sodium* 1 Publications Verification 8-CPT-2'-O-Me-cAMP sodium	Ras	Cardiovascular Disease
8-pCPT-2′-O-Me-cAMP (8-CPT-2'-O-Me-cAMP) sodium, an analog of cAMP, is an activator of exchange proteins activated by cAMP (Epac). 8-pCPT-2′-O-Me-cAMP sodium activates Epac1 (EC₅₀ = 2.2 μM), but not PKA (EC₅₀ >10 μM). 8-pCPT-2′-O-Me-cAMP sodium stimulates Epac-mediated Ca ²⁺ release in pancreatic β-cells in vitro. 8-pCPT-2′-O-Me-cAMP sodium is a Rap1 activator. 8-pCPT-2′-O-Me-cAMP sodium enhances the retinal pigment epithelium barrier against the pathological choroidal endothelial cell invasion that occurs in macular degeneration ^[2] .

HY-161834

RG100204 1 Publications Verification	Pyroptosis Aquaporin NOD-like Receptor (NLR) p38 MAPK	Infection Metabolic Disease Inflammation/Immunology
RG100204 is a selective, orally available inhibitor of the aquaporin AQP9. RG100204 directly inhibits AQP9 channel function, preventing the transmembrane transport of water, glycerol, and H ²O ². RG100204 reduces the activation of the NLRP3 inflammasome and p38 MAPK signaling pathways, thereby alleviating inflammation and pyroptosis. RG100204 reduces multi-organ dysfunction in a mouse sepsis model and shows glucose-regulating effects in diabetic db/db mice ^[2] .

HY-W011824

2′-O-Methyluridine	Endogenous Metabolite Apolipoprotein	Inflammation/Immunology Cancer
2’-O-Methyluridine is a modified nucleoside that can be found in T. thermophile tRNA. 2’-O-Methyluridine level in serum is decreased in patients with breast cancer ^[2] .

HY-W013260

2'-O-Methylguanosine	Nucleoside Antimetabolite/Analog Apoptosis DNA/RNA Synthesis	Infection Cancer
2'-O-Methylguanosine is a modified nucleoside produced in tRNAs by the action of tRNA guanosine-2’-O-methyltransferase. 2'-O-Methylguanosine results in apoptotic changes of cells ^[2].

HY-N0526

2"-O-Galloylhyperin 2 Publications Verification	Sirtuin Keap1-Nrf2 NF-κB ERK p38 MAPK JNK TSH Receptor Reactive Oxygen Species (ROS) SOD	Neurological Disease Inflammation/Immunology
2''-O-Galloylhyperin is an active natural compound with anti‑inflammatory, antioxidant, anti‑adipogenic, antifibrotic, and cytostatic activities. 2''-O-Galloylhyperin upregulates *SIRT1/Nrf2* signaling, inhibits NF-κB and MAPK (ERK1/2, p38, JNK) phosphorylation, suppresses TSHR activation, reduces ROS accumulation, and enhances SOD and GSH-Px activities. 2''-O-Galloylhyperin protects against LPS-induced tissue injury, enhances survival, and inhibits adipogenesis and fibrosis. 2"-O-Galloylhyperin can be used for the research of sepsis, acute lung injury, and thyroid eye disease ^[2] .

HY-N6821

2-O-α-D-Glucopyranosyl-L-ascorbic Acid	Drug Derivative	Inflammation/Immunology Cancer
2-O-α-D-Glucopyranosyl-L-ascorbic Acid is an orally active glucoside derivative of ascorbic acid. 2-O-α-D-Glucopyranosyl-L-ascorbic Acid can be hydrolyzed by α-glucosidase to release ascorbic acid. 2-O-α-D-Glucopyranosyl-L-ascorbic Acid inhibits melanin synthesis, prevents UV-induced cell damage, and promotes collagen synthesis in skin fibroblasts. 2-O-α-D-Glucopyranosyl-L-ascorbic Acid also induces oxidative stress to inhibit tumor growth. 2-O-α-D-Glucopyranosyl-L-ascorbic Acid can be used in research related to tumors, inflammation, and other conditions ^[2] .

HY-W101391

*DMT-2'O-Methyl-rU Phosphoramidite* 2'-O-Me-U Phosphoramidite	Phosphoramidites DNA/RNA Synthesis	Others
DMT-2'O-Methyl-rU Phosphoramidite (2'-O-Me-U Phosphoramidite) is a 2'-O-Me derivative, and can be used for oligonucleotide synthesis ^[2].

HY-W011552

2'-O-Methyladenosine	Endogenous Metabolite	Cardiovascular Disease
2'-O-Methyladenosine, a methylated adenine residue is found in urine of normals as well as in urine of adenosine deaminase (ADA) deficient patients. 2'-O-Methyladenosine exhibits unique hypotensive activities ^[2].

HY-N0534

*Vitexin-2"-O-rhamnoside*	DNA/RNA Synthesis Apoptosis PI3K Akt Caspase SOD Interleukin Related	Cardiovascular Disease Inflammation/Immunology Cancer
Vitexin-2"-O-rhamnoside is an orally active flavonoid glycoside. Vitexin-2"-O-rhamnoside inhibits Apoptosis, increases the phosphorylation levels of PI3K/Akt, inhibits caspase-3, SOD activity, and promotes cytokine (IL-2, IL-6, and IL-12) secretion. Vitexin-2"-O-rhamnoside strongly inhibits DNA synthesis in MCF-7 cells with an IC₅₀ of 17.5 μM. Vitexin-2"-O-rhamnoside enhances immune function and improves the absorption of active compounds. Vitexin-2"-O-rhamnoside has antioxidant activity. Vitexin-2"-O-rhamnoside is used in the study of cardiovascular disease and immune-related diseases ^[2] .

HY-23789

2′-O-(2-Methoxyethyl)guanosine 2'-O-MOE-rG	Nucleoside Antimetabolite/Analog DNA/RNA Synthesis	Others
2′-O-(2-Methoxyethyl)guanosine (2'-O-MOE-rG) is a 2'-O-methoxyethyl-modified nucleoside analogue and an important intermediate in the synthesis of nucleic acid drugs. 2′-O-(2-Methoxyethyl)guanosine neither effectively phosphorylated by cytosolic nucleoside kinases, nor are they incorporated into cellular DNA or RNA ^[2].

HY-W048491

2′-O-(2-Methoxyethyl)adenosine	DNA/RNA Synthesis Drug Derivative	Others
2′-O-(2-Methoxyethyl)adenosine is an ATP (HY-B2176) derivative. 2′-O-(2-Methoxyethyl)adenosine can be used for oligonucleotide synthesis .

HY-W048495

2'-O-(2-Methoxyethyl)-uridine	Nucleoside Antimetabolite/Analog	Cancer
2'-O-(2-Methoxyethyl)-uridine is a synthetic oligonucleotide conversed from uridine. 2'-O-(2-Methoxyethyl)-uridine has the potential for chemotherapeutic agents development .

HY-W585952

*Salicylic acid 2-O-β-D-glucoside* SA-2-O-β-D-glucoside	Drug Metabolite	Infection
Salicylic acid 2-O-β-D-glucoside (SA-2-O-β-D-glucoside) is the glucose-conjugated product of Salicylic Acid (HY-B0167) in plants. Salicylic acid 2-O-β-D-glucoside belongs to an inactive storage form. Salicylic acid 2-O-β-D-glucoside can be used in studies of plant pathogen infection .

HY-139988

2-O-DMT-Sulfonyldiethanol phosphoramidite	DNA/RNA Synthesis Phosphoramidites	Others
2-O-DMT-Sulfonyldiethanol phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.

HY-137878

2-O-(p-Nitrophenyl)-α-D-N-acetylneuraminic acid PNP-α-NeuNAc	Biochemical Assay Reagents	Others
2-O-(p-Nitrophenyl)-α-D-N-acetylneuraminic acid (PNP-α-NeuNAc) is a classic chromogenic substrate for neuraminidase. 2-O-(p-Nitrophenyl)-α-D-N-acetylneuraminic acid releases p-nitrophenol upon enzymatic hydrolysis, allowing quantification of enzyme activity and inhibitory effects via spectrophotometry. 2-O-(p-Nitrophenyl)-α-D-N-acetylneuraminic acid (PNP-α-NeuNAc) acts as a sialyl donor in the process of enzyme-catalyzed trans-sialylation ^[2].

HY-119445A

Sophorose monohydrate 2-O-beta-D-Glucopyranosyl-D-glucopyranose monohydrate	Biochemical Assay Reagents	Infection Others Cancer
Sophorose (2-O-beta-D-Glucopyranosyl-D-glucopyranose) monohydrate is the disaccharide component of microbial glycolipids, which are often used as biosurfactants due to their hydrophobicity. Sophorolipids also exhibit antibacterial, antifungal, spermicidal, virucidal, and anticancer activities. In studies of Trichoderma reesei fermentation, sophorose monohydrate has been identified as a potent inducer of cellulase gene expression .

HY-W570885

2'-O-MOE-rC	Phosphoramidites DNA/RNA Synthesis	Others
2'-O-MOE-rC is a 2'-O-MOE modified nucleoside. 2'-O-MOE-rC can be used for synthesis of DNA ^[2].

HY-131763

2'-O-MB-cAMP sodium 2'-O-Monobutyryl cyclic AMP sodium	Drug Intermediate	Others
2'-O-MB-cAMP (2'-O-Monobutyryl cyclic AM) sodium is an activatable proagent of Cyclic AMP (HY-B1511) .

HY-111639

2’-O,4’-C-Methyleneuridine	Nucleoside Antimetabolite/Analog	Others
2’-O,4’-C-Methyleneuridine (Compound 15a) is a bicyclic nucleoside.

HY-W570888

2'-O,4'-C-Methylenecytidine LNA-C(Bz)	Nucleoside Antimetabolite/Analog	Cancer
2'-O,4'-C-Methylenecytidine (LNA-C(Bz)) is a bicyclic nucleoside analogue with fixed N-type conformation. 2'-O,4'-C-Methylenecytidine can be used to synthesize oligonucleotides. 2'-O,4'-C-Methylenecytidine forms duplexes with complementary DNA and RNA strands ^[2].

HY-101082

*N6,2′-O-Dimethyladenosine*	Fat Mass and Obesity-associated Protein (FTO)	Metabolic Disease Cancer
N6,2′-O-Dimethyladenosine is a FTO substrate and reversible RNA modification. N6,2′-O-Dimethyladenosine acts as a demethylation substrate for FTO, which removes its methyl groups. N6,2′-O-Dimethyladenosine correlates with enhanced mRNA stability, improved translation efficiency and increased protein expression levels. N6,2′-O-Dimethyladenosine is applicable to research related to obesity and colorectal cancer ^[2].

HY-69014

2-O-Methylcytosine	DNA/RNA Synthesis Endogenous Metabolite	Cancer
2-O-Methylcytosine, an O-alkylated analogue a DNA adduct, is the damaged nucleobase .

HY-N6958

2-O-β-D-Glucopyranosyl-L-ascorbic acid 1 Publications Verification AA-2βG	Apoptosis HSP Reactive Oxygen Species (ROS) Keap1-Nrf2 Heme Oxygenase (HO)	Inflammation/Immunology Cancer
2-O-β-D-Glucopyranosyl-L-ascorbic acid (AA-2βG) is an orally active vitamin C derivative. 2-O-β-D-Glucopyranosyl-L-ascorbic acid exhibits multiple activities including antioxidant, anti-tumor and immunomodulatory effects. 2-O-β-D-Glucopyranosyl-L-ascorbic acid mediates tumor cell apoptosis, induces cell cycle arrest, scavenges free radicals and eliminates oxidative stress. 2-O-β-D-Glucopyranosyl-L-ascorbic acid can be used in studies related to cancer, inflammation and immunity .

HY-W353469

2-O-(α-D-Glucopyranosyl)glycerol (55% in water) Glucosylglycerol	Biochemical Assay Reagents	Others
2-O-(α-D-Glucopyranosyl) glycerol (55% in water) (Glucosylglycerol) is a glycerol glycoside and compatible solute. 2-O-(α-D-Glucopyranosyl) glycerol is isolable from the marine cyanobacterium Oscillatoria sp. 2-O-(α-D-Glucopyranosyl) glycerol (55% in water) acts as a salt stress protectant in Synechocystis sp. PCC 6803 ΔggpS cells. It enhances salt tolerance of Synechocystis sp. PCC 6803 ΔggpS cells and maintains cell division under salt stress ^[2].

HY-W011834R

2'-O-Methylcytidine (Standard)	Reference Standards HCV DNA/RNA Synthesis	Infection
2'-O-Methylcytidine (Standard) is the analytical standard of 2'-O-Methylcytidine. This product is intended for research and analytical applications. 2'-O-Methylcytidine is an orally active 2'-substituted nucleoside as a inhibitor of HCV replication with antiviral activity. 2'-O-Methylcytidine inhibits RNA-dependent RNA polymerase (NS5B)-catalyzed RNA synthesis in vitro, in a manner that is competitive with substrate nucleoside triphosphate ^[2] .

HY-N5141

*Isoscoparin-2′′O-glucoside*	Others	Others
Isoscoparin-2′′O-glucoside is a flavonoid that can be found in yellow grain mutant of rice. Isoscoparin-2′′O-glucoside shows antioxidant activity ^[2].

HY-W100234

*5-Methyl-2′-O-methyl-uridine* 2'-O-Methyl-5-methyluridine	Nucleoside Antimetabolite/Analog	Cancer
5-Methyl-2’-O-methyl-uridine (2'-O-methyl-5-methyluridine) is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis. 5-Methyl-2’-O-methyl-uridine is a modified nucleoside that can be found in tRNA isolated from rabbit liver ^[2].

HY-N11063

*Obtusifolin-2-O-glucoside*	Tyrosinase	Cancer
Obtusifolin-2-O-glucoside (compound 7) is a Tyrosinase inhibitor (IC₅₀=9.2 μM). Obtusifolin-2-O-glucoside can be isolated from cassia seed .

HY-W570886

2'-O-MOE-U	DNA/RNA Synthesis	Cancer
2'-O-MOE-U is a nucleic acid modification group (Phosphoramidite) with 3'-exonuclease inhibitory activity. 2'-O-MOE-U also exhibits gene silencing activity and double-stranded oligonucleotide stability. By forming steric interactions with 3'-exonuclease residues, 2'-O-MOE-U anchors the 3'-end of the siRNA guide strand in the hAgo2 PAZ domain, thereby regulating double-stranded thermal stability and enhancing base-pairing specificity. 2'-O-MOE-U does not induce IFNα production, can be incorporated at multiple sites of siRNA to enhance RNAi activity, and produces a synergistic effect with 2'-F modification. 2'-O-MOE-U has been widely used in studies related to breast cancer and other diseases ^[2].

HY-E70081

*mRNA Cap 2'-O-methyltransferase*	Biochemical Assay Reagents	Others
mRNA Cap 2'-O-methyltransferase uses S-adenosylmethionine (SAM) as a methyl donor to add a methyl group at the 2'-O position of the first nucleotide at the 5’ end of Cap-0 mRNA, resulting in Cap-1 structure. Cap-1 structure promotes translation efficiency, increasing subsequent protein expression .

HY-W048496

2'-O-(2-Methoxyethyl)-cytidine	Nucleoside Antimetabolite/Analog	Cancer
2'-O-(2-Methoxyethyl)-cytidine is a synthetic oligonucleotide derived from uridine. 2'-O-(2-Methoxyethyl)-cytidine has good hybridization properties and high stability, and can be used in the research of oligonucleotide chemotherapeutic agents .

HY-W013322

Ac-Tyr-OEt.H2O	Amino Acid Derivatives	Others
Ac-Tyr-OEt.H2O is a tyrosine derivative .

HY-W011834S

2'-O-Methylcytidine-d3	Isotope-Labeled Compounds HCV	Infection
2'-O-Methylcytidine-d₃ is deuterium labeled 2'-O-Methylcytidine (HY-W011834). 2'-O-Methylcytidine is a 2'-substituted nucleoside as a inhibitor of HCV replication. 2'-O-Methylcytidine inhibits RNA-dependent RNA polymerase (NS5B)-catalyzed RNA synthesis in vitro, in a manner that is competitive with substrate nucleoside triphosphate.

HY-116312

*8-pCPT-2′-O-Me-cAMP* 8-CPT-2'-O-Me-cAMP	Ras	Cardiovascular Disease
8-pCPT-2′-O-Me-cAMP (8-CPT-2'-O-Me-cAMP), an analog of cAMP, is an activator of exchange proteins activated by cAMP (Epac). 8-pCPT-2′-O-Me-cAMP activates Epac1 (EC₅₀ = 2.2 μM), but not PKA (EC₅₀ >10 μM). 8-pCPT-2′-O-Me-cAMP stimulates Epac-mediated Ca ²⁺ release in pancreatic β-cells in vitro. 8-pCPT-2′-O-Me-cAMP is a Rap1 activator. 8-pCPT-2′-O-Me-cAMP enhances the retinal pigment epithelium barrier against the pathological choroidal endothelial cell invasion that occurs in macular degeneration ^[2] .

HY-119445

Sophorose 2-O-beta-D-Glucopyranosyl-D-glucopyranose	Biochemical Assay Reagents	Others
Sophorose is a disaccharide component of microbial glycolipids produced by yeast called sophorolipids. Due to their hydrophobic nature, sophorolipids are commonly used as biosurfactants. Sophorolipids also exhibit antibacterial, antifungal, spermicidal, virucidal, and anticancer activities. Sophorose has been identified as a potent inducer of cellulase gene expression in Trichoderma reesei fermentation studies.

HY-W013260R

2'-O-Methylguanosine (Standard)	Reference Standards Nucleoside Antimetabolite/Analog Apoptosis DNA/RNA Synthesis	Infection Cancer
2'-O-Methylguanosine (Standard) is the analytical standard of 2'-O-Methylguanosine (HY-W013260). This product is intended for research and analytical applications. 2'-O-Methylguanosine is a modified nucleoside produced in tRNAs by the action of tRNA guanosine-2’-O-methyltransferase. 2'-O-Methylguanosine results in apoptotic changes of cells.

HY-W011824R

2′-O-Methyluridine (Standard) 1 Publications Verification	Reference Standards Endogenous Metabolite Apolipoprotein	Inflammation/Immunology Cancer
2′-O-Methyluridine (Standard) is the analytical standard of 2′-O-Methyluridine (HY-W001824). This product is intended for research and analytical applications. 2’-O-Methyluridine is a modified nucleoside that can be found in T. thermophile tRNA. 2’-O-Methyluridine level in serum is decreased in patients with breast cancer.

HY-W011552R

2'-O-Methyladenosine (Standard) 1 Publications Verification	Reference Standards Endogenous Metabolite	Cardiovascular Disease
2'-O-Methyladenosine (Standard) is the analytical standard of 2'-O-Methyladenosine. This product is intended for research and analytical applications. 2'-O-Methyladenosine, a methylated adenine residue is found in urine of normals as well as in urine of adenosine deaminase (ADA) deficient patients. 2'-O-Methyladenosine exhibits unique hypotensive activities ^[2].

HY-W011824S

2′-O-Methyluridine-d3	Isotope-Labeled Compounds Endogenous Metabolite Apolipoprotein	Inflammation/Immunology Cancer
2′-O-Methyluridine-d₃ is deuterium labeled 2′-O-Methyluridine (HY-W011824).2’-O-Methyluridine is a modified nucleoside that can be found in T. thermophile tRNA. 2’-O-Methyluridine level in serum is decreased in patients with breast cancer ^[2].

HY-153061

2’-O-Methylisocytidine	Nucleoside Antimetabolite/Analog	Others
2'-O-Methylisocytidine is a nucleoside compound .

HY-105006

Spongosine 2-Methoxyadenosine; 2-O-Methylisoguanosine	Nucleoside Antimetabolite/Analog	Cancer
Spongosine (2-Methoxyadenosine) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-W073183

Dibenzo-24-crown-8-ether	Biochemical Assay Reagents	Others
Dibenzo-24-crown-8-ether is a phase transfer catalyst that can reduce H ²PtCl ⁶·6H ²O and FeCl ²·4H ²O in a thermal system to synthesize 17 nm monodispersed iron-platinum (FePt) alloy nanoparticles .

HY-D1065

NIR-H2O2	Fluorescent Dye	Inflammation/Immunology
NIR-H2O2 is a cell-permeable near-infrared (NIR) fluorescent turn-on sensor. NIR-H2O2 has both absorption and emission in the NIR region. NIR-H2O2 responds to H₂O₂ with a large turn-on NIR fluorescence signal upon excitation in the NIR region. NIR-H2O2 is capable of imaging endogenously produced H₂O₂ in living cells and mice .

HY-W013260S1

2'-O-Methylguanosine-d3	Isotope-Labeled Compounds Apoptosis Nucleoside Antimetabolite/Analog	Others
2'-O-Methylguanosine-d₃ is deuterium labeled 2'-O-Methylguanosine (HY-W013260). 2'-O-Methylguanosine is a modified nucleoside produced in tRNAs by the action of tRNA guanosine-2’-O-methyltransferase. 2'-O-Methylguanosine results in apoptotic changes of cells.

HY-N12744

2-O-trans-p-Coumaroylalphitolic acid	Glucocorticoid Receptor	Metabolic Disease
2-O-trans-p-Coumaroylalphitolic acid (Zj7) is a triterpene which can be extracted from jujube plants. 2-O-trans-P-Coumaroyl alphitolic acid is a selective modulator of glucocorticoid receptor (GR). 2-O-trans-P-coumaroyl alphitolic acid can be used in the study of obesity .

HY-W353572

2-O-(6-Deoxy-α-L-galactopyranosyl)-D-galactose	Biochemical Assay Reagents	Others
2-O-(6-Deoxy-α-L-galactopyranosyl)-D-galactose is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

HY-142723

KCa2 channel modulator 1	Potassium Channel	Neurological Disease
KCa2 channel modulator 1 (compound 2o) is a potent subtype-selective positive modulator of K_Ca2 channel. KCa2 channel modulator 1 potentiates human K_Ca2.3 channels with an EC₅₀ value of 0.19 μM and 0.99 μM on the rat K_Ca2.2 channel subtype .

HY-131764

2'-O-MB-cGMP sodium 2′-O-Monobutyryl-cGMP sodium	Phosphodiesterase (PDE)	Others
2'-O-MB-cGMP (2′-O-Monobutyryl-cGMP) sodium is a cyclic GMP-specific phosphodiesterase inhibitor with an I₅₀ value of 35 µM. 2'-O-MB-cGMP (2′-O-Monobutyryl-cGMP) sodium inhibits Ca ²⁺ dependent phosphodiesterase hydrolysis using cAMP or cGMP as substrate .

HY-N12309

2′-O-Methylphloretin	Others	Others
2′-O-Methylphloretin (compound 3) is a flavonoid derivative. 2′-O-Methylphloretin can be isolated from the leaves of Melodorum siamensis. 2′-O-Methylphloretin inhibits the tumor cell line replication .

HY-69014R

2-O-Methylcytosine (Standard)	DNA/RNA Synthesis Endogenous Metabolite Reference Standards	Cancer
2-O-Methylcytosine (Standard) is the analytical standard of 2-O-Methylcytosine. This product is intended for research and analytical applications. 2-O-Methylcytosine, an O-alkylated analogue a DNA adduct, is the damaged nucleobase .

Cat. No.	Nombre del producto	Category	Target	Chemical Structure

HY-N0652

*2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside* 3 Publications Verification 2,3,4',5-Tetrahydroxystilbene 2-O-D-glucoside	Stilbenes Classification of Application Fields Polygonaceae Other Diseases Phenols Polyphenols Fallopia multiflora (Thunb.) Harald. Plants Disease Research Fields Source Classification	ERK NF-κB
2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside isolats from the roots of Polygonaceae species, inhibits the formation of 5-HETE, HHT and thromboxane B2. 2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside has hypotensive, anti-ageing, anti-inflammatory, hypolipidemic, cardioprotective, and neuroprotective actions ^[2].

HY-N0526

2"-O-Galloylhyperin 2 Publications Verification	Flavonols Structural Classification Classification of Application Fields Plants Flavonoids Pyrola calliantha H. Andr. Pyrolaceae Phenols Polyphenols Pyrola incarnata Fisch. ex DC. Inflammation/Immunology Disease Research Fields Source Classification	Sirtuin Keap1-Nrf2 NF-κB ERK p38 MAPK JNK TSH Receptor Reactive Oxygen Species (ROS) SOD
2''-O-Galloylhyperin is an active natural compound with anti‑inflammatory, antioxidant, anti‑adipogenic, antifibrotic, and cytostatic activities. 2''-O-Galloylhyperin upregulates *SIRT1/Nrf2* signaling, inhibits NF-κB and MAPK (ERK1/2, p38, JNK) phosphorylation, suppresses TSHR activation, reduces ROS accumulation, and enhances SOD and GSH-Px activities. 2''-O-Galloylhyperin protects against LPS-induced tissue injury, enhances survival, and inhibits adipogenesis and fibrosis. 2"-O-Galloylhyperin can be used for the research of sepsis, acute lung injury, and thyroid eye disease ^[2] .

HY-N0534

*Vitexin-2"-O-rhamnoside*	Cardiovascular Disease Flavonoids other families Classification of Application Fields Flavones Phenols Polyphenols Plants Disease Research Fields Source Classification	DNA/RNA Synthesis Apoptosis PI3K Akt Caspase SOD Interleukin Related
Vitexin-2"-O-rhamnoside is an orally active flavonoid glycoside. Vitexin-2"-O-rhamnoside inhibits Apoptosis, increases the phosphorylation levels of PI3K/Akt, inhibits caspase-3, SOD activity, and promotes cytokine (IL-2, IL-6, and IL-12) secretion. Vitexin-2"-O-rhamnoside strongly inhibits DNA synthesis in MCF-7 cells with an IC₅₀ of 17.5 μM. Vitexin-2"-O-rhamnoside enhances immune function and improves the absorption of active compounds. Vitexin-2"-O-rhamnoside has antioxidant activity. Vitexin-2"-O-rhamnoside is used in the study of cardiovascular disease and immune-related diseases ^[2] .

HY-N5114

*Isovitexin 2''-O-arabinoside* 2 Publications Verification	Flavonoids Classification of Application Fields Flavones Avena sativa Linn. Gramineae Other Diseases Phenols Polyphenols Plants Disease Research Fields Source Classification	Phosphatase
Isovitexin 2''-O-arabinoside is a flavonoid in plantlets of Avena sativa L. .

HY-N5124

Meloside A 4 Publications Verification Isovitexin 2''-O-glucoside; Isovitexin 2''-O-β-D-glucoside	Infection Structural Classification Flavonoids Classification of Application Fields Flavones Phenols Polyphenols Actaea dahurica Turcz. ex Fisch. & C. A. Mey. Plants Rhamnaceae Disease Research Fields Source Classification	Androgen Receptor Apoptosis Reactive Oxygen Species (ROS) Interleukin Related TGF-β Receptor
Meloside A (Isovitexin 2''-O-glucoside) is a flavonoid with antioxidant activity. Meloside A can inhibit cell apoptosis and ROS production. Meloside A can inhibit androgen receptor (AR) nuclear translocation and AR protein expression. Meloside A can reduce IL-6, TGF-β1 and DKK-1 levels. Meloside A can be used for the researches of inflammation and endocrinology, such as hair loss .

HY-N6964

Quercetin 3-O-β-D-(6''-p-coumaroyl)glucopyranosyl(1→2)-α-L-rhamnopyranoside Quercetin-3-O-[2-O-(6-O-p-hydroxyl-E-coumaroyl)-D-glucosyl]-(1→2)-L-rhamnoside	Flavonols Structural Classification Flavonoids Ginkgoaceae Classification of Application Fields Phenols Polyphenols Metabolic Disease Plants Ginkgo biloba Disease Research Fields Source Classification	Drug Derivative
Quercetin 3-O-β-D-(6''-p-coumaroyl) glucopyranosyl (1→2)-α-L-rhamnopyranoside (Quercetin-3-O-[2-O-(6-O-p-hydroxyl-E-coumaroyl)-D-glucosyl]-(1→2)-L-rhamnoside) is a flavonoid glycoside present in Ginkgo biloba leaves, with antioxidant activity. Quercetin 3-O-β-D-(6''-p-coumaroyl) glucopyranosyl (1→2)-α-L-rhamnopyranoside serves as the major antioxidant component in Shuxuening Injection ^[2].

HY-69014

2-O-Methylcytosine	Productos naturales Classification of Application Fields Endogenous metabolite Disease Research Fields Source Classification Cancer	DNA/RNA Synthesis Endogenous Metabolite
2-O-Methylcytosine, an O-alkylated analogue a DNA adduct, is the damaged nucleobase .

HY-N6958

2-O-β-D-Glucopyranosyl-L-ascorbic acid 1 Publications Verification AA-2βG	Structural Classification Classification of Application Fields Metabolic Disease Solanaceae Plants Lycium chinense Miller Disease Research Fields Saccharides Source Classification	Apoptosis HSP Reactive Oxygen Species (ROS) Keap1-Nrf2 Heme Oxygenase (HO)
2-O-β-D-Glucopyranosyl-L-ascorbic acid (AA-2βG) is an orally active vitamin C derivative. 2-O-β-D-Glucopyranosyl-L-ascorbic acid exhibits multiple activities including antioxidant, anti-tumor and immunomodulatory effects. 2-O-β-D-Glucopyranosyl-L-ascorbic acid mediates tumor cell apoptosis, induces cell cycle arrest, scavenges free radicals and eliminates oxidative stress. 2-O-β-D-Glucopyranosyl-L-ascorbic acid can be used in studies related to cancer, inflammation and immunity .

HY-W353469

2-O-(α-D-Glucopyranosyl)glycerol (55% in water) Glucosylglycerol	Structural Classification Marine algae Marine natural products Saccharides Monosaccharides Source Classification	Biochemical Assay Reagents
2-O-(α-D-Glucopyranosyl) glycerol (55% in water) (Glucosylglycerol) is a glycerol glycoside and compatible solute. 2-O-(α-D-Glucopyranosyl) glycerol is isolable from the marine cyanobacterium Oscillatoria sp. 2-O-(α-D-Glucopyranosyl) glycerol (55% in water) acts as a salt stress protectant in Synechocystis sp. PCC 6803 ΔggpS cells. It enhances salt tolerance of Synechocystis sp. PCC 6803 ΔggpS cells and maintains cell division under salt stress ^[2].

HY-N5119

*Kaempferol-3-O-(2''-O-β-D-glucopyl)-β-D-rutinoside*	Flavonoids other families Classification of Application Fields Flavones Other Diseases Phenols Polyphenols Plants Disease Research Fields Source Classification	Others
Kaempferol-3-O-(2''-O-β-D-glucopyl)-β-D-rutinoside is a natural glycoside that could be found in Camellia oleifera seeds .

HY-N9529

*Kaempferol 3-O-(2′′-O-α-rhamnosyl-6′′-O-malonyl-β-glucoside)*	Flavonols Flavonoids Classification of Application Fields Leguminosae Clitoria ternatea Linn. Other Diseases Phenols Polyphenols Plants Disease Research Fields Source Classification	Others
Kaempferol 3-O-(2′′-O-α-rhamnosyl-6′′-O-malonyl-β-glucoside) is a flavonoid glycoside compound .

HY-N5141

*Isoscoparin-2′′O-glucoside*	Flavonoids Classification of Application Fields Flavones Gramineae Other Diseases Phenols Polyphenols Oryza sativa L. Plants Disease Research Fields Source Classification	Others
Isoscoparin-2′′O-glucoside is a flavonoid that can be found in yellow grain mutant of rice. Isoscoparin-2′′O-glucoside shows antioxidant activity ^[2].

HY-N11063

*Obtusifolin-2-O-glucoside*	Cassia tora (L.) Roxb. Quinones Monophenols Leguminosae Anthraquinones Phenols Plants Source Classification	Tyrosinase
Obtusifolin-2-O-glucoside (compound 7) is a Tyrosinase inhibitor (IC₅₀=9.2 μM). Obtusifolin-2-O-glucoside can be isolated from cassia seed .

HY-N0406

2"-O-beta-L-galactopyranosylorientin	Flavonoids other families Classification of Application Fields Plants Inflammation/Immunology Disease Research Fields Isoflavones Source Classification	P-glycoprotein
2"-O-beta-L-galactopyranosylorientin is extracted from the flowers of Trollius ledebouri. 2"-O-beta-L-galactopyranosylorientin involves transporter mediated efflux in addition to passive diffusion and is the substrate of multidrug resistance protein 2 (MRP2). Anti-inflammatory effect ^[2] .

HY-N1745

2'-O-Methylisoliquiritigenin	Chalcones Flavonoids Leguminosae Phenols Polyphenols Plants Glycyrrhiza uralensis Fisch. Medicago sativa L. Source Classification	5-HT Receptor Dopamine Receptor GABA Receptor
2'-O-Methylisoliquiritigenin, isolated from the Arachis species, up-regulates 5-HT, NE, DA and GABA pathways, but does not put a very significant effect on ne NE pathway .

HY-N5047

*Orientin-2''-O-p-trans-coumarate*	Flavonoids other families Classification of Application Fields Flavones Other Diseases Phenols Polyphenols Plants Disease Research Fields Source Classification	Others
Orientin-2''-O-p-trans-coumarate is a flavonoid found in Trigonella foenum-graecum, with potent antioxidant activity .

HY-N3516

*Oxyresveratrol 2-O-β-D-glucopyranoside*	Stilbenes Classification of Application Fields Phenols Polyphenols Metabolic Disease Plants Moraceae Disease Research Fields Source Classification Morus alba Linn.	Tyrosinase
Oxyresveratrol 2-O-β-D-glucopyranoside is a phenolic compound isolated from Morus nigra root and is an effective tyrosinase inhibitor with an IC₅₀ of 29.75 μM .

HY-N3020

Brandioside 2'-Acetylpoliumoside; 2'-O-Acetylpoliumoside	Classification of Application Fields Simple Phenylpropanols Other Diseases Phenols Polyphenols Scrophulariaceae Phenylpropanoids Plants Disease Research Fields Source Classification Brandisia hancei Hook. f.	Others
Brandioside is a natural phenylpropanoid glycoside from Brandisia hancei .

HY-N16554

2′′-O-Glucosylrutin	Structural Classification Flavonoids Flavones Leguminosae Plants Source Classification	Others
2′-O-Glucosylrutin (Compound 32) is a type of flavonol glycoside and can be found in Lablab Flos Alba .

HY-N12282

*Isovitexin 2′′-O-rhamnoside*	Structural Classification Flavonoids Tetrastigma hemsleyanum Diels et Gilg Flavones Plants Vitaceae Source Classification	Others
Isovitexin 2′′-O-rhamnoside, a phenolic, has antioxidant and antiproliferative activities .

HY-N12077

*Eurycomanol 2-O-β-D-glucopyranoside*	Simaroubaceae Plants Saccharides Monosaccharides Source Classification	Parasite
Eurycomanol 2-O-β-D-glucopyranoside (compound 4) is a natural product that can be obtained from Eurycoma longifolia. Eurycomanol 2-O-β-D-glucopyranoside has the potential for anti-malarial research .

HY-N16550

*Isoorientin-2''-O-rhamnoside*	Structural Classification Flavonoids Flavones Passifloraceae Passiflora biflora Lam. Plants Source Classification	Others
Isoorientin-2''-O-rhamnoside is one of the C-glycosylflavones isolated from leaves of Passlflora biflora .

HY-N0652R

*2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside (Standard)* 2,3,4',5-Tetrahydroxystilbene 2-O-D-glucoside (Standard)	Structural Classification Stilbenes Polygonaceae Phenols Polyphenols Fallopia multiflora (Thunb.) Harald. Plants Source Classification	Reference Standards ERK NF-κB
2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside (Standard) is the analytical standard of 2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside. This product is intended for research and analytical applications. 2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside isolats from the roots of Polygonaceae species, inhibits the formation of 5-HETE, HHT and thromboxane B2. 2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside has hypotensive, anti-ageing, anti-inflammatory, hypolipidemic, cardioprotective, and neuroprotective actions ^[2].

HY-W011552R

2'-O-Methyladenosine (Standard) 1 Publications Verification	Structural Classification Productos naturales Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
2'-O-Methyladenosine (Standard) is the analytical standard of 2'-O-Methyladenosine. This product is intended for research and analytical applications. 2'-O-Methyladenosine, a methylated adenine residue is found in urine of normals as well as in urine of adenosine deaminase (ADA) deficient patients. 2'-O-Methyladenosine exhibits unique hypotensive activities ^[2].

HY-N2203A

Vitexin2''-O-p-trans-coumarate	Flavonoids Flavones Leguminosae Plants Trigonella foenum-graecum Linn. Source Classification	Others
Vitexin2''-O-p-trans-coumarate is a flavonoid, can be isolated from the Et acetate-soluble fraction of the ethanolic extract of the seeds of Trigonella foenum-graecum. Vitexin2''-O-p-trans-coumarate strongly promotes 2BS cell proliferation induced by H₂O₂ .

HY-N2289

2''-O-Rhamnosylicariside II	Flavonols Flavonoids Classification of Application Fields Other Diseases Phenols Polyphenols Epimedium brevicornu Maxim. Plants Berberidaceae Disease Research Fields Source Classification	Others
2''-O-Rhamnosylicariside II is a flavonoid glycoside compound and might be beneficial for improving postmenopausal osteoporosis.

HY-N10869

Pseudolaric acid C2-O-β-D-glucoside	Pinaceae Terpenoids Diterpenoids Pseudolarix amabilis (J. Nelson) Rehder Plants Source Classification	Others
Pseudolaric acid C2-O-β-D-glucoside is a natural product isolated from Pseudolarix kaempferi .

HY-N11538

*Quercetin-3-O-(2′′-O-galloyl)-β-D-glucopyranoside*	Flavonoids Classification of Application Fields Polygonaceae Plants Other Flavonoids Inflammation/Immunology Disease Research Fields Polygonum capitatum Buch.-Ham. ex D. Don Prodr Source Classification	Others
Quercetin-3-O-(2′′-O-galloyl)-β-D-glucopyranoside is a orally active phenolic compound that can be isolated from the Geranium species. Quercetin-3-O-(2′′-O-galloyl)-β-D-glucopyranoside has anti-inflammatory activities and has potential application in edema and aortic endothelium-dependent relaxation injury .

HY-W127369

*1-O-Hexadecyl-2-O-docosahexaenoyl-sn-glycero-3-phosphorylcholine* PC(O-16:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z))	Productos naturales Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
1-O-Hexadecyl-2-O-docosahexaenoyl-sn-glycero-3-phosphorylcholine is an endogenous metabolite present in Urine that can be used for the research of Obesity ^[2].

HY-N12744

2-O-trans-p-Coumaroylalphitolic acid	Triterpenes Terpenoids Actaea dahurica Turcz. ex Fisch. & C. A. Mey. Plants Rhamnaceae Source Classification	Glucocorticoid Receptor
2-O-trans-p-Coumaroylalphitolic acid (Zj7) is a triterpene which can be extracted from jujube plants. 2-O-trans-P-Coumaroyl alphitolic acid is a selective modulator of glucocorticoid receptor (GR). 2-O-trans-P-coumaroyl alphitolic acid can be used in the study of obesity .

HY-N8928

2''-O-Galloylmyricitrin Desmanthin 1	Flavonoids Flavones Polygonaceae Plants Polygonum capitatum Buch.-Ham. ex D. Don Prodr Source Classification	Others
2''-O-Galloylmyricitrin (Desmanthin 1) is a product that can be isolated from The herbs of Impatiens balsamina. .

HY-N5039

*1,2-O-Dilinoleoyl-3-O-Beta-D-Galactopyranosylracglycerol* 1,2-O-Dilinoleoyl-3-O-β-D-galactopyranosylracglycerol	Productos naturales Sparganium stoloniferum (Graebn.) Buch.-Ham. ex Juz. Classification of Application Fields Other Diseases Plants Disease Research Fields Sparganiaceae Source Classification	Others
1,2-O-Dilinoleoyl-3-O-Beta-D-Galactopyranosylracglycerol is isolated from the flower of Magnolia denudate.

HY-N12309

2′-O-Methylphloretin	Melodorum siamensis Plants Annonaceae Source Classification	Others
2′-O-Methylphloretin (compound 3) is a flavonoid derivative. 2′-O-Methylphloretin can be isolated from the leaves of Melodorum siamensis. 2′-O-Methylphloretin inhibits the tumor cell line replication .

HY-69014R

2-O-Methylcytosine (Standard)	Structural Classification Productos naturales Endogenous metabolite Source Classification	DNA/RNA Synthesis Endogenous Metabolite Reference Standards
2-O-Methylcytosine (Standard) is the analytical standard of 2-O-Methylcytosine. This product is intended for research and analytical applications. 2-O-Methylcytosine, an O-alkylated analogue a DNA adduct, is the damaged nucleobase .

HY-N8747

*Vitexin 2''-O-(4'''-O-acetyl)rhamnoside* 4'''-O-Acetyl-2''-O-rhamnosylvitexin	Saussurea medusa Maxim. Flavonoids Flavones Crataegus laevigata (Poir.) DC. Labiatae Rosaceae Plants Source Classification	Others
Vitexin 2''-O-(4'''-O-acetyl)rhamnoside (4'''-O-Acetyl-2''-O-rhamnosylvitexin) is a Diterpenoids product that can be isolated from the needles and twigs of Taxus cuspidata. .

HY-N15570

2-O-Methylatromentin	Microorganisms Phenols Polyphenols Source Classification	Interleukin Related TNF Receptor
2-O-Methylatromentin is an anti-neuroinflammatory agent. 2-O-Methylatromentin shows inhibitory activity on the production of pro-inflammatory cytokines TNF-α, IL-6 and IL-1β in Lipopolysaccharides (HY-D1056) (LPS) -induced BV-2 microglial cells. 2-O-Methylatromentin can be used for the study of neuroinflammatory related diseases .

HY-N2203

Vitexin2''-O-p-coumarate	Flavonoids other families Classification of Application Fields Flavones Other Diseases Phenols Polyphenols Plants Disease Research Fields Source Classification	Others
Vitexin2''-O-p-coumarate is isolated from fenugreek seeds. Vitexin2''-O-p-coumarate strongly promotes 2BS cell proliferation induced by H₂O₂ ^[2].

HY-N8608

2''-O-Acetyl-platyconic acid A	Terpenoids Platycodon grandiflorus (Jacq.) A. DC. Campanulaceae Diterpenoids Plants Source Classification	Others
2''-O-Acetyl-platyconic acid A is an active compound. 2''-O-Acetyl-platyconic acid A can be used for the research of various biochemical .

HY-N0526R

2"-O-Galloylhyperin (Standard)	Flavonols Structural Classification Flavonoids Pyrola calliantha H. Andr. Pyrolaceae Phenols Polyphenols Plants Pyrola incarnata Fisch. ex DC. Source Classification	Reference Standards Sirtuin Keap1-Nrf2 NF-κB ERK p38 MAPK JNK TSH Receptor Reactive Oxygen Species (ROS) SOD
2"-O-Galloylhyperin (Standard) is the analytical standard of 2"-O-Galloylhyperin (HY-N0526). This product is intended for research and analytical applications. 2''-O-Galloylhyperin is an active natural compound with anti‑inflammatory, antioxidant, anti‑adipogenic, antifibrotic, and cytostatic activities. 2''-O-Galloylhyperin upregulates *SIRT1/Nrf2* signaling, inhibits NF-κB and MAPK (ERK1/2, p38, JNK) phosphorylation, suppresses TSHR activation, reduces ROS accumulation, and enhances SOD and GSH-Px activities. 2''-O-Galloylhyperin protects against LPS-induced tissue injury, enhances survival, and inhibits adipogenesis and fibrosis. 2"-O-Galloylhyperin can be used for the research of sepsis, acute lung injury, and thyroid eye disease ^[2] .

HY-W357141

*Methyl 2-O-β-D-glucopyranosylbenzoate* Methyl salicylate 2-O-β-D-glucopyranoside	Structural Classification Piperaceae Piper crocatum Ruiz & Pav. Plants Saccharides Monosaccharides Source Classification	Drug Derivative
Methyl 2-O-β-D-glucopyranosylbenzoate (Methyl salicylate 2-O-β-D-glucopyranoside) (Compound 11) is a phenolic compound. Methyl 2-O-β-D-glucopyranosylbenzoate can be isolated from the leaves of Metapanax delavayi. Methyl 2-O-β-D-glucopyranosylbenzoate has anti-benign prostatic hyperplasia activities and significantly inhibits the proliferation of BPH-1 cells. β-Phenylethyl β-D-glucoside can be used for prostatitis research .

HY-N0534R

*Vitexin-2"-O-rhamnoside (Standard)*	Structural Classification Flavonoids other families Flavones Phenols Polyphenols Plants Source Classification	Reference Standards DNA/RNA Synthesis Apoptosis PI3K Akt Caspase SOD Interleukin Related
Vitexin-2"-O-rhamnoside (Standard) is the analytical standard of Vitexin-2"-O-rhamnoside (HY-N0534). This product is intended for research and analytical applications. Vitexin-2"-O-rhamnoside is an orally active flavonoid glycoside. Vitexin-2"-O-rhamnoside inhibits Apoptosis, increases the phosphorylation levels of PI3K/Akt, inhibits caspase-3, SOD activity, and promotes cytokine (IL-2, IL-6, and IL-12) secretion. Vitexin-2"-O-rhamnoside strongly inhibits DNA synthesis in MCF-7 cells with an IC₅₀ of 17.5 μM. Vitexin-2"-O-rhamnoside enhances immune function and improves the absorption of active compounds. Vitexin-2"-O-rhamnoside has antioxidant activity. Vitexin-2"-O-rhamnoside is used in the study of cardiovascular disease and immune-related diseases ^[2] .

HY-N9856

*Juncusol 2-O-glucoside*	Juncus effusus Linn. Monophenols Juncaceae Phenols Plants Source Classification	Others
Juncusol 2-O-glucoside is an active compound.

HY-N0406R

2"-O-beta-L-galactopyranosylorientin (Standard)	Structural Classification Flavonoids other families Plants Isoflavones Source Classification	Reference Standards Others
2"-O-beta-L-galactopyranosylorientin (Standard) is the analytical standard of 2"-O-beta-L-galactopyranosylorientin. This product is intended for research and analytical applications. 2"-O-beta-L-galactopyranosylorientin is extracted from the flowers of Trollius ledebouri. 2"-O-beta-L-galactopyranosylorientin involves transporter mediated efflux in addition to passive diffusion and is the substrate of multidrug resistance protein 2 (MRP2). Anti-inflammatory effect ^[2] .

HY-N1742

2''-O-Coumaroyljuglanin 2''-O-p-Cumaroyleuglanin; Kaempferol 3-O-[2′′-(E)-p-coumaroyl]-α-L-arabinofuranoside	Flavonoids Prunus spinosa L. Flavones Rosaceae Plants Source Classification	Others
2''-O-Coumaroyljuglanin (2''-O-p-Cumaroyleuglanin) is a flavonoid which can be isolated from the flowers of Prunus spinosa .

HY-N11880

2-O-Sinapoyl makisterone A	Fibraurea recisa Pierre Plants Menispermaceae Steroids Source Classification	COX
2-O-Sinapoyl makisterone A (compound 2), a sinapinic acid-ecdysterone hybrid, is a selective inhibitor of COX-2. 2-O-Sinapoyl makisterone A significantly inhibits the expression of COX-2 protein .

HY-N8125

*Rhaponticin 2′′-O-gallate*	Stilbenes Classification of Application Fields Polygonaceae Rheum officinale Baill. Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields Source Classification	Others
Rhaponticin 2''-O-gallate, as a stilbene glucoside gallate, inhibits NO production .

HY-N4009

*Iriflophenone 2-O-α-rhamnoside*	Thymelaeaceae Phenols Polyphenols Plants Aquilaria sinensis (Lour.) Spreng. Source Classification	Others
Iriflophenone 2-O-α-rhamnoside can be isolated from the leaves of Aquilaria sinensis. Iriflophenone 2-O-α-rhamnoside has a half-life value of 2.44 min in rats at the administration of 25 mg/kg .

HY-N3166

*Onitisin 2'-O-glucoside*	Onychium japonicum (Thunb.) Kunze Terpenoids Sesquiterpenes Pteridaceae Plants Source Classification	Others
Onitisin 2'-O-glucoside is a Sesquiterpenoids product that can be isolated from the herbs of Onychium japonicum .

HY-N0955

*(+)-Puerol B 2''-O-glucoside*	Leguminosae Phenols Pueraria montana (Loureiro) Merrill Plants Source Classification	Others
(+)-Puerol B 2''-O-glucoside is a Phenols product that can be isolated from the herbs of Pueraria lobata .

HY-N9936

Saikosaponin S5 2''-O-acetylsaikosaponin A	Triterpenes Terpenoids Umbelliferae Plants Ambrosia arborescens Mill. Source Classification	Others
Saikosaponin S5 (2''-O-acetylsaikosaponin A) is a Iridoids product that can be isolated from the barks of Ailanthus integrifolia .

Cat. No.	Nombre del producto	Chemical Structure

HY-B1776AS1

Spermidine-13C4 hydrochloride 1 Publications Verification
Spermidine- ¹³C₄ (hydrochloride) is the ¹³C-labeled Spermidine trihydrochloride. Spermidine hydrochloride maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine hydrochloride significantly decreases the H2O2 and O2.- contents .

HY-Y0882S1

Hydroxylamine-d3 hydrochloride

Hydroxylamine-d₃ (hydrochloride) is the deuterium labeled Hydroxyamine hydrochloride. Hydroxylamine hydrochloride is a selective Monoamine oxidase (MAO) inhibitor used for inhibiting of platelet aggregation. Hydroxylamine hydrochloride is an intermediate of nitrogen cycle in aerobic ammonium oxidizers microorganisms, such as ammonium oxidizing bacteria (AOB), ammonium oxidizing archaea (AOA) and complete ammonium oxidizing bacteria (comammox). Hydroxylamine hydrochloride impacts NO and N₂O emissions by aerobic ammonium oxidizers microorganisms and inhibits nitrite oxidizing bacteria (NOB) activity ^[2] .

HY-B1776S

Spermidine-d6 1 Publications Verification
Spermidine-d₆ is the deuterium labeled Spermidine . Spermidine maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine significantly decreases the H2O2 and O2.- contents ^[2].

HY-B1776AS

Spermidine-d8 hydrochloride
Spermidine-d₈ (hydrochloride)e is the deuterium labeled Spermidine trihydrochloride. Spermidine hydrochloride maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine hydrochloride significantly decreases the H2O2 and O2.- contents .

HY-W011834S

2'-O-Methylcytidine-d3
2'-O-Methylcytidine-d₃ is deuterium labeled 2'-O-Methylcytidine (HY-W011834). 2'-O-Methylcytidine is a 2'-substituted nucleoside as a inhibitor of HCV replication. 2'-O-Methylcytidine inhibits RNA-dependent RNA polymerase (NS5B)-catalyzed RNA synthesis in vitro, in a manner that is competitive with substrate nucleoside triphosphate.

HY-W011824S

2′-O-Methyluridine-d3
2′-O-Methyluridine-d₃ is deuterium labeled 2′-O-Methyluridine (HY-W011824).2’-O-Methyluridine is a modified nucleoside that can be found in T. thermophile tRNA. 2’-O-Methyluridine level in serum is decreased in patients with breast cancer ^[2].

HY-41494S1

o-Toluic acid-13C
o-Toluic acid- ¹³C is the ¹³C labeled o-Toluic acid . o-Toluic acid (2-Methylbenzoic acid) is a benzoic acid substituted by a methyl group at position 2. O-Toluic acid plays a role as a xenobiotic metabolite.

HY-41494S

O-Toluic acid-d7
O-Toluic acid-d₇ is the deuterium labeled o-Toluic acid . o-Toluic acid (2-Methylbenzoic acid) is a benzoic acid substituted by a methyl group at position 2. O-Toluic acid plays a role as a xenobiotic metabolite.

HY-W753672

2'-O-Methyladenosine-d3
2'-O-Methyl Adenosine-d₃ is deuterium labeled 2'-O-Methyl Adenosine. 2'-O-Methyl Adenosine, a methylated adenine residue is found in urine of normals as well as in urine of adenosine deaminase (ADA) deficient patients. 2'-O-Methyl Adenosine exhibits unique hypotensive activities ^[2].

HY-W101495S3

Boc-Leu-OH·H2O-d7
Boc-Leu-OH·H2O-d₇ is the deuterium labeled Boc-Leu-OH·H2O.

HY-W101495S2

Boc-Leu-OH·H2O-d10
Boc-Leu-OH·H2O-d₁₀ is the deuterium labeled Boc-Leu-OH·H2O .

HY-W744002

2'-O-Methyl-d3 Paclitaxel
2'-O-Methyl-d₃ Paclitaxel is the deuterium labeled 2'-O-Methyl Paclitaxel (HY-W741186).

HY-W727768

*Salicylic acid 2-O-β-D-glucoside-d4*
Salicylic acid 2-O-β-D-glucoside-d₄ is deuterium labeled Salicylic acid 2-O-β-D-glucoside .

HY-150658S

*DMT-2′O-TBDMS-rA(ac) phosphoramidite-15N*
DMT-2′O-TBDMS-rA(ac) phosphoramidite-15N is the ¹⁵N labeled DMT-2′O-TBDMS-rA(ac) phosphoramidite .

HY-W101495S1

Boc-Leu-OH·H2O-d3
Boc-Leu-OH·H2O-d₃ is the deuterium labeled Boc-Leu-OH·H2O .

HY-W357141S1

*MeSA 2-O-b-D-glucoside-d7*
MeSA 2-O-b-D-glucoside-d₇ is the deuterium labeled MeSA 2-O-b-D-glucoside .

HY-W357141S

*MeSA 2-O-b-D-glucoside-d3*
MeSA 2-O-b-D-glucoside-d₃ is the deuterium labeled MeSA 2-O-b-D-glucoside .

HY-W357141S2

*MeSA 2-O-b-D-glucoside-d4*
MeSA 2-O-b-D-glucoside-d₄ is the deuterium labeled MeSA 2-O-b-D-glucoside .

HY-W101495S

Boc-Leu-OH·H2O-13C
Boc-Leu-OH·H₂O- ¹³C is a ¹³C-labeled Boc-Leu-OH (HY-W101495). Boc-Leu-OH hydrate (N-Boc-L-leucine monohydrate) is an amino acid derivative with a Boc protecting group, which can be used to synthesize L-prolyl-L-leucyl-glycinamide peptide, a peptide mimetic with dopamine receptor modulatory activity .

HY-150980S

*1,2-O-Isopropylidene-β-L-idofuranuronic-6-13C acid γ-lactone*
1,2-O-Isopropylidene-β-L-idofuranuronic-6- ¹³C acid γ-lactone is the ¹³C labeled 1,2-O-Isopropylidene-β-L-idofuranuronic acid γ-lactone .

HY-150981S

*1,2-O-Isopropylidene-a-D-glucofuranuronic-6-13C acid, γ-lactone*
1,2-O-Isopropylidene-a-D-glucofuranuronic-6- ¹³C acid, γ-lactone is the ¹³C labeled 1,2-O-Isopropylidene-β-L-idofuranuronic acid, γ-lactone .

HY-167925S

2'-O-Methyl Uridine-d3
2'-O-Methyl Uridine-d₃ is the deuterium labeled Rec 15/2615 (HY-167925). Rec 15/2615 is a potent α(1)-adrenergic agonist that stimulates small cholangiocyte proliferation through the activation of calcium-dependent signaling pathways.

HY-131990S

MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH-d5
MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH-d₅ is deuterated labeled MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH .

HY-W714570

o-Tolylglyoxylic Acid Methyl Ester-d7
o-Tolylglyoxylic Acid Methyl Ester-d₇ (Methyl 2-oxo-2-(o-tolyl)acetate-d₇) is the deuterium labeled Methyl 2-oxo-2-(o-tolyl)acetate (HY-W278295).

HY-115702S

1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine-d4

1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine-d₄ ((Rac)-PAF (C16)-d₄) is the deuterium labeled 1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine. 1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine is an endogenous inflammatory lipid mediator. 1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine acts as a high-affinity agonist for PAFR (GPCR), inducing platelet aggregation, vascular permeability, and leukocyte chemotaxis at extremely low concentrations. 1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine exerts its effects via cell surface receptors to regulate inflammation .

HY-151909S

Endothall-3,4,4,5,5,6 H2O-d6
Endothall-3,4,4,5,5,6 H2O-d₆ is the deuterium labeled 7-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid hydrate (HY-W714211).

HY-W048482S4

rU Phosphoramidite-15N
rU Phosphoramidite- ¹⁵N (DMT-2'O-TBDMS-rU phosphoramidite- ¹⁵N) is ¹⁵N labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

HY-W048482S3

rU Phosphoramidite-15N2
rU Phosphoramidite- ¹⁵N₂ (DMT-2'O-TBDMS-rU phosphoramidite- ¹⁵N₂) is ¹⁵N labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

HY-W048482S2

rU Phosphoramidite-13C9
rU Phosphoramidite- ¹³C₉ (DMT-2'O-TBDMS-rU phosphoramidite- ¹³C₉) is ¹³C-labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

HY-W048482S

rU Phosphoramidite-13C2,d1
rU Phosphoramidite- ¹³C₂,d₁ (DMT-2'O-TBDMS-rU phosphoramidite- ¹³C₂,d₁) is deuterium and ¹³C-labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

HY-W048482S1

rU Phosphoramidite-13C9,15N2
rU Phosphoramidite- ¹³C₉, ¹⁵N₂ (DMT-2'O-TBDMS-rU phosphoramidite- ¹³C₉, ¹⁵N₂) is ¹³C and ¹⁵N-labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

HY-W707595

O-tert-Butyl-2-hydroxy efavirenz-d5
O-tert-Butyl-2-hydroxy efavirenz-d₅ is the deuterium labeled O-tert-Butyl-2-hydroxy Efavirenz (HY-W744274).

HY-W721191

O-2-Amino-2-methylpropyl bilastine-d6
O-2-Amino-2-methylpropyl bilastine-d₆ is the deuterium labeled O-tert-Butyl-dimethylsilyl curcumin.

HY-W753153

O-6-Methyl-2'-deoxyguanosine-d3
O-6-Methyl-2'-deoxyguanosine-d₃ is the deuterium labeled O-6-Methyl-2'-deoxyguanosine.

HY-N7092S21

D-Fructose-18O-2
D-Fructose- ¹⁸O-2 is the ¹⁸O labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants .

HY-W777959

Azasetron Hydrochloride-13C,d3

Azasetron Hydrochloride- ¹³C,d₃ is the deuterium and ¹³C-labeled Azasetron (HY-B0019). Azasetron ((Rac)-SENS-401 free base) is an antiemetic drug with 5-HT3 receptor antagonist activity. Azasetron is often used as a preventive measure for postoperative nausea and vomiting or chemotherapy-induced nausea and vomiting. Azasetron does not impair neutrophil chemotaxis or phagocytosis and does not scavenge O(-)(2) or H(2)O(2) generated by cell-free systems .

HY-B0389S31

D-Glucose-18O-2
D-Glucose- ¹⁸O-2 is the ¹⁸O labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecule

HY-W767399

8-Bromo-2'-deoxyguanosine-13C,15N2

8-Bromo-2'-deoxyguanosine- ¹³C, ¹⁵N2 is the ¹³C- and ¹⁵N-labeled 8-Bromo-2'-deoxyguanosine (HY-W011168). 8-Bromo-2'-deoxyguanosine is an inflammation-related DNA halogenated adduct and an early biomarker of inflammation-induced oxidative tissue damage. The formation of 8-Bromo-2'-deoxyguanosine precedes that of oxidative and nitrative products, and it can be generated via the MPO-H₂O₂-Cl ^--Br ^- system. 8-Bromo-2'-deoxyguanosine serves as the immunogen for preparing the monoclonal antibody mAb8B3, which can be used to detect early DNA modifications in preclinical models; its urinary level also increases significantly in inflammatory disease models. 8-Bromo-2'-deoxyguanosine can also be produced in the dermis of UV-B irradiated mice, and the extract of Coprinus comatus significantly reduces its level. 8-Bromo-2'-deoxyguanosine finds applications in studies related to inflammatory diseases, diabetes, hepatocellular carcinoma, and UV-B induced skin inflammation ^[2] .

HY-W738271

Veratryl alcohol-13C

Veratryl alcohol- ¹³C (3,4-Dimethoxybenzyl alcohol- ¹³C) is the ¹³C-labeled Veratryl alcohol (HY-107858). Veratryl alcohol (3,4-Dimethoxybenzyl alcohol) is a secondary metabolite of lignin-degrading fungi, commonly used as a substrate for lignin peroxidase (LiP) to measure lignin degradation activity. Veratryl alcohol protects LiP from inactivation by H2O2 and prevents the accumulation of LiP III compounds. Veratryl alcohol also acts as a stabilizer for manganese-dependent peroxidases (MnP). Veratryl alcohol is a quorum-sensing inhibitor (QSI) and exhibits antibacterial efficacy ^[2] .

HY-W767614

O6-(2-Hydroxypropyl)-2'-deoxyguanosine-d3
O6-(2-Hydroxypropyl)-2'-deoxyguanosine-d₃ is the deuterium labeled O6-(2-Hydroxypropyl)-2'-deoxyguanosine.

HY-166873S

Fluvoxamine-d3
Fluvoxamine-d₃ is deuterium labeled (Z)-5-Methoxy-1-(4-(trifluoromethyl)phenyl)pentan-1-one O-(2-aminoethyl) oxime (Fluvoxamine Impurity) .

HY-Y0882S

Hydroxylamine-15N hydrochloride

Hydroxylamine- ¹⁵N hydrochloride is the ¹⁵N-labeled Hydroxylamine hydrochloride (HY-Y0882). Hydroxylamine hydrochloride is a selective Monoamine oxidase (MAO) inhibitor used for inhibiting of platelet aggregation. Hydroxylamine hydrochloride is an intermediate of nitrogen cycle in aerobic ammonium oxidizers microorganisms, such as ammonium oxidizing bacteria (AOB), ammonium oxidizing archaea (AOA) and complete ammonium oxidizing bacteria (comammox). Hydroxylamine hydrochloride impacts NO and N2O emissions by aerobic ammonium oxidizers microorganisms and inhibits nitrite oxidizing bacteria (NOB) activity ^[2].

HY-W778954

2,2-Dimethyl-1,3-dioxolane-4-methanol-13C3
2,2-Dimethyl-1,3-dioxolane-4-methanol- ¹³C₃ ((2,2-Dimethyl-[1,3] dioxane-4-yl)-methanol- ¹³C₃) is the ¹³C-labeled 2,2-Dimethyl-1,3-dioxolane-4-methanol (HY-Y1372).

Cat. No.	Nombre del producto	Target	Áreas de investigación	Chemical Structure

HY-131990G

MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH	ADC Linker	Cancer
MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH GMP is a GMP grade MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (HY-131990). MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-45672G

Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH	ADC Linker	Cancer
Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH GMP is a GMP grade Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (HY-45672). Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is an ADC Linker that can be used to synthesize Drug-Linker Conjugates for ADC. Especially for the synthesis of Deruxtecan (HY-13631E), a toxic drug-linker conjugate .

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