fac-[Re(CO)3(L6)(H2O)][NO3]
fac-[Re(CO)3(L6)(H2O)][NO3] (compound 6), the rhenium(I) tricarbonyl aqua complex, is an anticancer agent associated with mitochondrial dysfunction. fac-[Re(CO)3(L6)(H2O)][NO3] is cytotoxic to prostate cancer cells, IC50=50 nM (PC-3 cells). fac-[Re(CO)3(L6)(H2O)][NO3] mainly accumulates in the nucleus, down-regulates ATP production in PC3 cells, and promotes apoptosis. However, fac-[Re(CO)3(L6)(H2O)][NO3] did not induce necrosis, pyrodeath and autophagy.
For research use only. We do not sell to patients.
- Formula: C24H14N5O7ReS
- Molecular Weight:702.67
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
![fac-[Re(CO)3(L6)(H2O)][NO3] Chemical Structure](https://file.medchemexpress.com/product_pic/hy-155718.gif "Click to View fac-[Re(CO)3(L6)(H2O)][NO3] Chemical Structure")
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Biological Activity
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Chemical Information
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Help & FAQs
Biological Activity
Chemical Information
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Molecular Weight 702.67
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Formula C24H14N5O7ReS
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SMILES
[OH2][Re+]1([N]2=CC=CC3=C2C4=C(C5=C3N=C(N5)C6=CC7=C(S6)C=CC=C7)C=CC=[N]41)([C]=O)([C]=O)[C]=O.[O-][N+]([O-])=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
fac-[Re(CO)3(L6)(H2O)][NO3] Related Classifications
HY-155718 Related Classifications
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