2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor Cannabinoid Receptor
  4. CB2R/5-HT1AR agonist 1

CB2R/5-HT1AR agonist 1 (Compound 2o) is an orally active partial agonist of the CB2 receptor (EC50=479.6 nM). CB2R/5-HT1AR agonist 1 is a full agonist of 5-HT1A receptor (EC50=2.7 μM). CB2R/5-HT1AR agonist 1 exhibits anti-anxiety and anti-depressive effects. CB2R/5-HT1AR agonist 1 possesses favorable pharmacokinetic properties.

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CB2R/5-HT1AR agonist 1 Chemical Structure

CB2R/5-HT1AR agonist 1 Chemical Structure

CAS No. : 2821085-76-9

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CB2R/5-HT1AR agonist 1 Related Antibodies

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Description

CB2R/5-HT1AR agonist 1 (Compound 2o) is an orally active partial agonist of the CB2 receptor (EC50=479.6 nM). CB2R/5-HT1AR agonist 1 is a full agonist of 5-HT1A receptor (EC50=2.7 μM). CB2R/5-HT1AR agonist 1 exhibits anti-anxiety and anti-depressive effects. CB2R/5-HT1AR agonist 1 possesses favorable pharmacokinetic properties[1].

IC50 & Target

EC50: 479.6 nM (CB2)[1].
EC50: 2.7 μM (5-HT1A)[1].
Molecular Weight

383.52

Formula

C24H33NO3
CAS No.
SMILES

CCCCC1(C2=C(C(O)=C([C@H]3[C@@H](CCC(C)=C3)C(C)=C)C(O)=C2)C(N)=O)CC1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CB2R/5-HT1AR agonist 1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CB2R/5-HT1AR agonist 12821085-76-95-HT ReceptorCannabinoid ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorDepressionAnxietyInhibitorinhibitorinhibit

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