CHIKV nsP2 protease-IN-2
CHIKV nsP2 protease-IN-2 (Compound 2o) is a allosteric nonstructural protein 2 helicase (nsP2hel) inhibitor with IC50s of 0.5 μM and 0.9 μM for nsP2 ATPase and RNA unwindase, respectively. CHIKV nsP2 protease-IN-2 has broad-spectrum antialphaviral activity against chikungunya virus (CHIKV), Mayaro virus (MAYV), and Venezuelan equine encephalitis virus (VEEV) (EC50 of 120 nM for CHIKV-nLuc). CHIKV nsP2 protease-IN-2 can be used for alphaviruses infections research.
For research use only. We do not sell to patients.
- CAS No.: 3107145-13-8
- Formula: C26H38N2O4S
- Molecular Weight:474.66
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All DNA/RNA Synthesis Isoforms
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Biological Activity
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Helicase |
Chemical Information
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CAS No. 3107145-13-8
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Molecular Weight 474.66
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Formula C26H38N2O4S
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SMILES
O=C(N(CC1)CCC21CC(CN(CCCC3)S3(=O)=O)CCO2)C4(C5=CC=CC=C5)CCCC4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)