5'-DMT-2'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite
Based on 1 Customer Validation
5'-DMT-2'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 875302-45-7
- Formula: C46H63N4O9PSi
- Molecular Weight:875.07
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
Description
Chemical Information
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CAS No. 875302-45-7
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Appearance Solid
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Molecular Weight 875.07
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Formula C46H63N4O9PSi
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Color White to off-white
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SMILES
CC(C)N(C(C)C)P(O[C@H]1[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](C2=CN(C)C(NC2=O)=O)O[C@@H]1COC(C3=CC=CC=C3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)OCCC#N
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Synonyms
N1-Methylpseudouridine CEP
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (114.28 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.1428 mL | 5.7138 mL | 11.4277 mL | 28.5691 mL |
| 5 mM | 0.2286 mL | 1.1428 mL | 2.2855 mL | 5.7138 mL | |
| 10 mM | 0.1143 mL | 0.5714 mL | 1.1428 mL | 2.8569 mL | |
| 15 mM | 0.0762 mL | 0.3809 mL | 0.7618 mL | 1.9046 mL | |
| 20 mM | 0.0571 mL | 0.2857 mL | 0.5714 mL | 1.4285 mL | |
| 25 mM | 0.0457 mL | 0.2286 mL | 0.4571 mL | 1.1428 mL | |
| 30 mM | 0.0381 mL | 0.1905 mL | 0.3809 mL | 0.9523 mL | |
| 40 mM | 0.0286 mL | 0.1428 mL | 0.2857 mL | 0.7142 mL | |
| 50 mM | 0.0229 mL | 0.1143 mL | 0.2286 mL | 0.5714 mL | |
| 60 mM | 0.0190 mL | 0.0952 mL | 0.1905 mL | 0.4762 mL | |
| 80 mM | 0.0143 mL | 0.0714 mL | 0.1428 mL | 0.3571 mL | |
| 100 mM | 0.0114 mL | 0.0571 mL | 0.1143 mL | 0.2857 mL |