2′-O-Methylguanosine 5′-monophosphate
2′-O-Methylguanosine 5′-monophosphate is the nucleotide complex group (pGm) of the ribosome and is primarily used for DNA conjugation. Today's antibodies recognize pGm, in descending order of importance, as the parent base, the methylated ribose moiety, and the phosphate group. 2′-O-Methylguanosine 5′-monophosphate can also be used to prepare RNA vaccines as a 5′-terminal nucleotide to block the RNA molecule.
For research use only. We do not sell to patients.
- CAS No.: 24121-01-5
- Formula: C11H16N5O8P
- Molecular Weight:377.25
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All DNA/RNA Synthesis Isoforms
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Biological Activity
Description
Chemical Information
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CAS No. 24121-01-5
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Molecular Weight 377.25
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Formula C11H16N5O8P
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SMILES
O[C@H]1[C@@H](OC)[C@H](N2C(NC(N)=NC3=O)=C3N=C2)O[C@@H]1COP(O)(O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Vold BS. Preparation and specificity of antibodies directed toward the ribose methylated nucleotide, et al. Preparation and specificity of antibodies directed toward the ribose methylated nucleotide, 2'-O-methylguanosine 5'-monophosphate. Biochim Biophys Acta. 1981 Sep 28;655(2):265-7. [Content Brief]
[2]. Urushibara T, et al. A modified structure at the 5'-terminus of mRNA of vaccinia virus. FEBS Lett. 1975 Jan 1;49(3):385-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)