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IM-54 

Cat. No.: HY-108351 Purity: >99.0%
Handling Instructions

IM-54 is a selective inhibitor of oxidative stress-induced necrosis. IM-54 shows potent inhibitory activities against H2O2-induced necrosis. IM-54 acts as a potential cardioprotective agent and biological tools for investigating the molecular mechanisms of cell death.

For research use only. We do not sell to patients.

IM-54 Chemical Structure

IM-54 Chemical Structure

CAS No. : 861891-50-1

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Description

IM-54 is a selective inhibitor of oxidative stress-induced necrosis. IM-54 shows potent inhibitory activities against H2O2-induced necrosis. IM-54 acts as a potential cardioprotective agent and biological tools for investigating the molecular mechanisms of cell death[1][2].

In Vitro

IM-54 is found to selectively inhibit oxidative stress-induced necrosis, but it does not inhibit apoptosis induced by various anticancer drugs or Fas ligand, or necroptosis[1].
IM-54 shows strong inhibition of H2O2-induced necrosis, with an IC50 of 0.25 μM against HL-60 cells treated with H2O2[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

325.40

Formula

C₁₉H₂₃N₃O₂

CAS No.

861891-50-1

SMILES

O=C(C(C1=CN(C)C2=C1C=CC=C2)=C3NCCCCC)N(C)C3=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
References

Purity: >99.0%

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Keywords:

IM-54IM54IM 54Othersoxidativestressnecrosisischemia-reperfusionI/RinjuriesarrhythmiacardioprotectiveInhibitorinhibitorinhibit

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IM-54
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HY-108351
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