861891-50-1
861891-50-1
Chemical Structure
IM-54
- CAS. Nr.: 861891-50-1
- Formula:C19H23N3O2
- Molecular Weight:325.40
IUPAC Name: 1-methyl-3-(1-methyl-1H-indol-3-yl)-4-(pentylamino)-1H-pyrrole-2,5-dione
InChIKey: SGLOMINNEBLJFF-UHFFFAOYSA-N
SMILES: O=C(C(C1=CN(C)C2=C1C=CC=C2)=C3NCCCCC)N(C)C3=O
Biological Activity: IM-54 is a selective inhibitor of oxidative stress-induced necrosis. IM-54 shows potent inhibitory activity against H2O2-induced necrosis. IM-54 acts as a potential cardioprotective agent and biological tool for investigating the molecular mechanisms of cell death[1][2].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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IM-54 | 99.06% | IM-54 is a selective inhibitor of oxidative stress-induced necrosis. IM-54 shows potent inhibitory activity against H2O2-induced necrosis. IM-54 acts as a potential cardioprotective agent and biological tool for investigating the molecular mechanisms of cell death. | ||||||||||||||||||||
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IM-54 (Standard) | ≥98% | IM-54 (Standard) is the analytical standard of IM-54 (HY-108351). This product is intended for research and analytical applications. IM-54 is a selective inhibitor of oxidative stress-induced necrosis. IM-54 shows potent inhibitory activity against H2O2-induced necrosis. IM-54 acts as a potential cardioprotective agent and biological tool for investigating the molecular mechanisms of cell death. | ||||||||||||||||||||
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References
- [1]. Kosuke Dodo, et al. Indolylmaleimide Derivative IM-17 Shows Cardioprotective Effects in Ischemia-Reperfusion Injury. ACS Med Chem Lett. 2018 Mar 8; 9(3): 182-187. [Content Brief]
- [2]. Mikiko Sodeoka, et al. Development of selective inhibitors of necrosis. Chem Rec. 2010 Oct;10(5):308-14. [Content Brief]
