ZA10
ZA10 is a selective TRPM2 channel inhibitor, with an IC50 value of 8.1 μM. ZA10 can effectively suppress intracellular Ca2+ overload triggered by TRPM2 channel activation. ZA10 significantly reduce the mortality of SH-SY5Y cells induced by H2O2. ZA10 can be used for the study of ischemia-reperfusion injury, inflammation, or other neurodegenerative diseases.
For research use only. We do not sell to patients.
- CAS No.: 2696407-24-4
- Formula: C25H26N4O2
- Molecular Weight:414.50
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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TRPM2 8.1 μM (IC50) |
Chemical Information
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CAS No. 2696407-24-4
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Molecular Weight 414.50
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Formula C25H26N4O2
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SMILES
O=C(C1=CC2=CC=CC=C2O1)C3=C(C)N=C4N(CCN(CC)CC)C5=CC=CC=C5N43
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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