EGFR-IN-160
EGFR-IN-160 (Compound R12) is an EGFR inhibitor (IC50 values are 1.62, 0.49 and 0.98 μM for EGFRWT, EGFRT790M and EGFRL858R/T790M/C797S, respectively). EGFR-IN-160 induces G2/M and S phase arrest and apoptosis in NCI-H522 cells, and has anticancer activity. EGFR-IN-160 has antioxidant effects against DPPH (IC50: 12.11 µM) and H2O2 (IC50: 8.89 µM).
For research use only. We do not sell to patients.
- CAS No.: 2172879-84-2
- Formula: C15H12N2O4
- Molecular Weight:284.27
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All EGFR Isoforms
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Biological Activity
Chemical Information
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CAS No. 2172879-84-2
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Molecular Weight 284.27
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Formula C15H12N2O4
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SMILES
COC1=CC(C2=CC(C3=CC=CO3)=NC(O)=N2)=CC=C1O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)