2172879-84-2

EGFR-IN-160 Chemical Structure
2172879-84-2

Chemical Structure

EGFR-IN-160

  • CAS No.: 2172879-84-2
  • Formula:C15H12N2O4
  • Molecular Weight:284.27

SMILES: COC1=CC(C2=CC(C3=CC=CO3)=NC(O)=N2)=CC=C1O

Biological Activity: EGFR-IN-160 (Compound R12) is an EGFR inhibitor (IC50 values are 1.62, 0.49 and 0.98 μM for EGFRWT, EGFRT790M and EGFRL858R/T790M/C797S, respectively). EGFR-IN-160 induces G2/M and S phase arrest and apoptosis in NCI-H522 cells, and has anticancer activity. EGFR-IN-160 has antioxidant effects against DPPH (IC50: 12.11 µM) and H2O2 (IC50: 8.89 µM)[1].

Cat. No. Product Name Purity Description Pricing
HY-173619 		EGFR-IN-160 EGFR-IN-160 (Compound R12) is an EGFR inhibitor (IC50 values are 1.62, 0.49 and 0.98 μM for EGFRWT, EGFRT790M and EGFRL858R/T790M/C797S, respectively). EGFR-IN-160 induces G2/M and S phase arrest and apoptosis in NCI-H522 cells, and has anticancer activity. EGFR-IN-160 has antioxidant effects against DPPH (IC50: 12.11 µM) and H2O2 (IC50: 8.89 µM).
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This product is a controlled substance and not for sale in your territory.
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