Zinc Protoporphyrin (Standard)
Based on 1 Customer Validation
Zinc Protoporphyrin (Standard) is the analytical standard of Zinc Protoporphyrin. This product is intended for research and analytical applications. Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an orally active and competitive heme oxygenase-1 (HO-1) inhibitor and markedly attenuates the protective effects of Phloroglucinol (PG) against H2O2. Zinc Protoporphyrin is used as a screening marker of iron deficiency in individual pregnant women and children, but also to assess population iron status in combination with haemoglobin concentration. Zinc Protoporphyrin has anti-cancer activity.
For research use only. We do not sell to patients.
- Purity: 97.80%
- CAS No.: 15442-64-5
- Formula: C34H32N4O4Zn
- Molecular Weight:626.02
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 15442-64-5
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Appearance Solid
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Molecular Weight 626.02
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Formula C34H32N4O4Zn
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Color Brown to dark brown
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SMILES
OC(CCC1=C(C=C2[N]3=C4C(C)=C2CCC(O)=O)[N-]([Zn+2]35[N]6=C7C=C(C(C=C)=C8C)[N-]5C8=C4)C(C=C6C(C=C)=C7C)=C1C)=O
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Synonyms
Zn(II)-protoporphyrin IX (Standard); ZnPP (Standard); Zinc Protoporphyrin-9 (Standard)
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Park C, et al. Protective Effect of Phloroglucinol on Oxidative Stress-Induced DNA Damage and Apoptosisthrough Activation of the Nrf2/HO-1 Signaling Pathway in HaCaT Human Keratinocytes. Mar Drugs. 2019 Apr 13;17(4). [Content Brief]
[2]. Mwangi MN, et al. Diagnostic utility of zinc protoporphyrin to detect iron deficiency in Kenyan pregnant women. BMC Med. 2014 Nov 26;12:229. [Content Brief]
[3]. Nowis D, et al. Zinc protoporphyrin IX, a heme oxygenase-1 inhibitor, demonstrates potent antitumor effects but is unable to potentiate antitumor effects of chemotherapeutics in mice. BMC Cancer. 2008 Jul 11;8:197. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Zinc Protoporphyrin (Standard) Related Classifications
HY-101193R Related Classifications
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- Zinc Protoporphyrin (Standard)
- 15442-64-5
- Zn(II)-protoporphyrin IX (Standard)
- ZnPP (Standard)
- Zinc Protoporphyrin-9 (Standard)
- Reference Standards
- Reactive Oxygen Species (ROS)
- Endogenous Metabolite
- Apoptosis
- heme
- oxygenase-1
- HO-1
- Phloroglucinol
- H2O2
- screening
- marker
- iron
- deficiency,anti-cancer
- Inhibitor
- inhibitor
- inhibit