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Perfluorodecalin  (Synonyms: PP 5; Perfluorodecahydronaphthalene)

Cat. No.: HY-108298 Purity: ≥98.0%
COA Handling Instructions

Molarity Calculator

Perfluorodecalin liquids are largrly used in vitreoretinal surgery. Perfluorodecalin with tamponade lasting more than two days is detrimental to the retina in the case of rabbit. Perfluorodecalin can be used for the research of giant retinal tears. Perfluorodecalin is a non-toxic, non-flammable, thermally stable, non-bio-accumulating O2-carrier and used as artificial blood. Perfluorodecalin enhances bone regeneration and cell viability.

For research use only. We do not sell to patients.

Perfluorodecalin Chemical Structure

Perfluorodecalin Chemical Structure

CAS No. : 306-94-5

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Based on 1 publication(s) in Google Scholar

Perfluorodecalin Related Antibodies

Top Publications Citing Use of Products

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  • Purity & Documentation

  • References

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Description

Perfluorodecalin liquids are largrly used in vitreoretinal surgery. Perfluorodecalin with tamponade lasting more than two days is detrimental to the retina in the case of rabbit. Perfluorodecalin can be used for the research of giant retinal tears[1][2]. Perfluorodecalin is a non-toxic, non-flammable, thermally stable, non-bio-accumulating O2-carrier and used as artificial blood[3]. Perfluorodecalin enhances bone regeneration and cell viability[4][5].

In Vitro

Perfluorodecalin prolongs the cells survival in anaerobic environment, enhances the radiopacity, injectability, cohesion of bone cements and the bone regeneration[4]. Perfluorodecalin (10% v/v) ameliorates hypoxia and increases cell viability in transplantation of encapsulated islets[5].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Perfluorodecalin Related Antibodies

Cell Proliferation Assay[5]

Cell Line: BM cells
Concentration:
Incubation Time: 21 days
Result: Increased number of BM cells.

RT-PCR[5]

Cell Line: islets
Concentration: 10% v/v
Incubation Time:
Result: Decreased HIF-1α expression and increased VEGF expression.
In Vivo

Perfluorodecalin (1.1-1.5 ml/eye) induces inflammation and retinal damage in albino rabbits[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Albino rabbits[2]
Dosage: 1.1-1.5 ml for each eye
Administration: injection into vitreous cavity
Result: Induced appearance of foam cells, preretinal membranes, and the interface necrosis.
Molecular Weight

462.08

Formula

C10F18
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

FC12C(F)(F)C(F)(F)C(F)(F)C(F)(F)C1(F)C(F)(F)C(F)(F)C(F)(F)C2(F)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (216.41 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1641 mL 10.8206 mL 21.6413 mL
5 mM 0.4328 mL 2.1641 mL 4.3283 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥98.0%

COA (253 KB) CNMR (172 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.1641 mL 10.8206 mL 21.6413 mL 54.1032 mL
5 mM 0.4328 mL 2.1641 mL 4.3283 mL 10.8206 mL
10 mM 0.2164 mL 1.0821 mL 2.1641 mL 5.4103 mL
15 mM 0.1443 mL 0.7214 mL 1.4428 mL 3.6069 mL
20 mM 0.1082 mL 0.5410 mL 1.0821 mL 2.7052 mL
25 mM 0.0866 mL 0.4328 mL 0.8657 mL 2.1641 mL
30 mM 0.0721 mL 0.3607 mL 0.7214 mL 1.8034 mL
40 mM 0.0541 mL 0.2705 mL 0.5410 mL 1.3526 mL
50 mM 0.0433 mL 0.2164 mL 0.4328 mL 1.0821 mL
60 mM 0.0361 mL 0.1803 mL 0.3607 mL 0.9017 mL
80 mM 0.0271 mL 0.1353 mL 0.2705 mL 0.6763 mL
100 mM 0.0216 mL 0.1082 mL 0.2164 mL 0.5410 mL
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Perfluorodecalin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Perfluorodecalin306-94-5PP 5 PerfluorodecahydronaphthalenePP5PP-5Othersvitreoretinal surgerydetrimentalretinagiant retinal tearsisletBM cellsInhibitorinhibitorinhibit

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