306-94-5
Chemical Structure
Perfluorodecalin
Synonym(s): PP 5; Perfluorodecahydronaphthalene
- CAS No.: 306-94-5
- Formula:C10F18
- Molecular Weight:462.08
IUPAC Name: perfluorodecahydronaphthalene
InChIKey: UWEYRJFJVCLAGH-UHFFFAOYSA-N
SMILES: FC12C(F)(F)C(F)(F)C(F)(F)C(F)(F)C1(F)C(F)(F)C(F)(F)C(F)(F)C2(F)F
Biological Activity: Perfluorodecalin liquids are largrly used in vitreoretinal surgery. Perfluorodecalin with tamponade lasting more than two days is detrimental to the retina in the case of rabbit. Perfluorodecalin can be used for the research of giant retinal tears[1][2]. Perfluorodecalin is a non-toxic, non-flammable, thermally stable, non-bio-accumulating O2-carrier and used as artificial blood[3]. Perfluorodecalin enhances bone regeneration and cell viability[4][5].
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Perfluorodecalin | 98.0% | Perfluorodecalin liquids are largrly used in vitreoretinal surgery. Perfluorodecalin with tamponade lasting more than two days is detrimental to the retina in the case of rabbit. Perfluorodecalin can be used for the research of giant retinal tears. Perfluorodecalin is a non-toxic, non-flammable, thermally stable, non-bio-accumulating O2-carrier and used as artificial blood. Perfluorodecalin enhances bone regeneration and cell viability. | ||||||||||||||||||||
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Perfluorodecalin (Standard) | ≥98% | Perfluorodecalin (Standard) is the analytical standard of Perfluorodecalin (HY-108298). This product is intended for research and analytical applications. Perfluorodecalin liquids are largrly used in vitreoretinal surgery. Perfluorodecalin with tamponade lasting more than two days is detrimental to the retina in the case of rabbit. Perfluorodecalin can be used for the research of giant retinal tears. Perfluorodecalin is a non-toxic, non-flammable, thermally stable, non-bio-accumulating O2-carrier and used as artificial blood. Perfluorodecalin enhances bone regeneration and cell viability. | ||||||||||||||||||||
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- [1]. Orzalesi N, et al. Experimental short-term tolerance to perfluorodecalin in the rabbit eye: a histopathological study. Curr Eye Res. 1998;17(8):828-835. [Content Brief]
- [2]. Bourke RD, et al. Experimental long-term vitreous replacement with purified and nonpurified perfluorodecalin. Am J Ophthalmol. 1994;118(3):403-404. [Content Brief]
- [3]. Spahn DR. Blood substitutes. Artificial oxygen carriers: perfluorocarbon emulsions. Crit Care. 1999;3(5):R93-7. [Content Brief]
- [4]. Tamimi F, et al., Perfluorodecalin and bone regeneration. Eur Cell Mater. 2013 Jan 2;25:22-36. [Content Brief]
- [5]. Rodriguez-Brotons A, et al., Comparison of Perfluorodecalin and HEMOXCell as Oxygen Carriers for Islet Oxygenation in an In Vitro Model of Encapsulation. Tissue Eng Part A. 2016 Dec;22(23-24):1327-1336. [Content Brief]
