MitoTEMPOL
Based on 3 publication(s) in Google Scholar
MitoTEMPOL is a a mitochondria-targeted nitroxide that reduces mitochondrial O2-to H2O2.
For research use only. We do not sell to patients.
- Purity: 99.9%
- CAS No.: 1101113-39-6
- Formula: C32H42BrNO2P*
- Molecular Weight:583.56
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Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) MitoTEMPOL
More
Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 1101113-39-6
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Appearance Solid
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Molecular Weight 583.56
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Formula C32H42BrNO2P*
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Color Brown to orange
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SMILES
[O]N1C(C)(CC(CC1(C)C)OCCCCC[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)C.[Br-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Publications (3)
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Journal Impact Factor
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Most Recent
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Cell Rep Med
Vorapaxar enhanced mitochondria-associated ferroptosis primes cancer immunotherapy via targeting FOXO1/HMOX1 axis. [Abstract]2025 Sep 25:102371. PMID: 41005298 -
Int J Dent
The ROS/CaMK II/β-Catenin Signaling Axis Affects the Osteogenic Potential of BMSCs and Disrupts Implant Osseointegration: An In Vitro Study. [Abstract]2025 Aug 15:2025:5566776. PMID: 40861924 -
bioRxiv
2025 Nov 13:2025.11.11.687895. PMID: 41292779
Solvent & Solubility
DMF : 50 mg/mL (85.68 mM; Need ultrasonic and warming)
Ethanol : 50 mg/mL (85.68 mM; Need ultrasonic and warming)
DMSO : 50 mg/mL (85.68 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMF / Ethanol / DMSO | 1 mM | 1.7136 mL | 8.5681 mL | 17.1362 mL | 42.8405 mL |
| 5 mM | 0.3427 mL | 1.7136 mL | 3.4272 mL | 8.5681 mL | |
| 10 mM | 0.1714 mL | 0.8568 mL | 1.7136 mL | 4.2840 mL | |
| 15 mM | 0.1142 mL | 0.5712 mL | 1.1424 mL | 2.8560 mL | |
| 20 mM | 0.0857 mL | 0.4284 mL | 0.8568 mL | 2.1420 mL | |
| 25 mM | 0.0685 mL | 0.3427 mL | 0.6854 mL | 1.7136 mL | |
| 30 mM | 0.0571 mL | 0.2856 mL | 0.5712 mL | 1.4280 mL | |
| 40 mM | 0.0428 mL | 0.2142 mL | 0.4284 mL | 1.0710 mL | |
| 50 mM | 0.0343 mL | 0.1714 mL | 0.3427 mL | 0.8568 mL | |
| 60 mM | 0.0286 mL | 0.1428 mL | 0.2856 mL | 0.7140 mL | |
| 80 mM | 0.0214 mL | 0.1071 mL | 0.2142 mL | 0.5355 mL |
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