1,7-Dimethyluric acid
Based on 1 Customer Validation
1,7-Dimethyluric acid is an N-methylated uric acid and purine derivative, as well as a caffeine metabolite. When 1,7-Dimethyluric acid is acted upon by peroxidase in the presence of H2O2, it follows the same oxidation pathway to generate a UV-absorbing intermediate, which decays via first-order kinetics. 1,7-Dimethyluric acid can adsorb onto pyrolytic graphite electrodes, but not onto glassy carbon electrodes or platinum electrodes. The N-methylation modification of its pyrimidine ring prevents ring contraction of the diol intermediate, and no NMR evidence of O-alkylation is observed during propylation under the test conditions.
For research use only. We do not sell to patients.
- Purity: 99.9%
- CAS No.: 33868-03-0
- Formula: C7H8N4O3
- Molecular Weight:196.16
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Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Human Endogenous Metabolite |
1,7-Dimethyluric acid undergoes electrochemical oxidation, yielding N-methylurea and 1-methylalloxan at pH 3.0, and 1-methyl-5-hydroxyhydantoin-5-(N-methylcarboxamide) at pH 7.0, across PGE, GCE, and Pt electrodes[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 33868-03-0
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Appearance Solid
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Molecular Weight 196.16
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Formula C7H8N4O3
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Color White to off-white
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SMILES
O=C(N1C)NC2=C(N(C)C(N2)=O)C1=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : 10 mg/mL (50.98 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.0979 mL | 25.4894 mL | 50.9788 mL | 127.4470 mL |
| 5 mM | 1.0196 mL | 5.0979 mL | 10.1958 mL | 25.4894 mL | |
| 10 mM | 0.5098 mL | 2.5489 mL | 5.0979 mL | 12.7447 mL | |
| 15 mM | 0.3399 mL | 1.6993 mL | 3.3986 mL | 8.4965 mL | |
| 20 mM | 0.2549 mL | 1.2745 mL | 2.5489 mL | 6.3723 mL | |
| 25 mM | 0.2039 mL | 1.0196 mL | 2.0392 mL | 5.0979 mL | |
| 30 mM | 0.1699 mL | 0.8496 mL | 1.6993 mL | 4.2482 mL | |
| 40 mM | 0.1274 mL | 0.6372 mL | 1.2745 mL | 3.1862 mL | |
| 50 mM | 0.1020 mL | 0.5098 mL | 1.0196 mL | 2.5489 mL |
1,7-Dimethyluric acid Related Classifications
HY-126061 Related Classifications
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