Dual AChE-MAO B-IN-4
Dual AChE-MAO B-IN-4 (compound 7) is a dual AChE/MAO-B inhibitor, with IC50 values of 261 nM and 15 nM, respectively. Dual AChE-MAO B-IN-4 protects against oxidative damage induced by H2O2 and 6-OHDA in SH-SY5Y cells. Dual AChE-MAO B-IN-4 can penetrate the central nervous system in a cell model that mimics the blood-brain barrier. Dual AChE-MAO B-IN-4 can be used in the study of neurological diseases such as Alzheimer's disease (AD).
For research use only. We do not sell to patients.
- Formula: C24H23NO4S
- Molecular Weight:421.51
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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MAO-B 15 nM (IC50) |
AChE 261 nM (IC50) |
Chemical Information
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Molecular Weight 421.51
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Formula C24H23NO4S
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SMILES
O=C1C=C(CO)C2=C(O1)C=C(OCC3=CC=C(CN(C)CC4=CSC=C4)C=C3)C=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)