2. Cell Cycle/DNA Damage Epigenetics
  3. Sirtuin
  4. 2'/3'-O-Acetyl-ADP-ribose sodium

2'/3'-O-Acetyl-ADP-ribose sodium is an inhibitor of cell division and oocyte maturation. 2'/3'-O-Acetyl-ADP-ribose sodium causes delay or arrest of oocyte maturation and blastomere division in embryos. 2'/3'-O-Acetyl-ADP-ribose sodium is produced by Sir2 family deacetylases during the coupling of histone/protein deacetylation with β-NAD+ cleavage. In neutral or weakly alkaline aqueous solutions, the direct enzymatic product forms of 2'/3'-O-Acetyl-ADP-ribose sodium, namely the 2'-O-acetyl form and the 3'-O-acetyl form, undergo intramolecular lactone exchange reaction and interconvert with each other.

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2'/3'-O-Acetyl-ADP-ribose sodium

2'/3'-O-Acetyl-ADP-ribose sodium Chemical Structure

CAS No. : 1312013-29-8

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2'/3'-O-Acetyl-ADP-ribose sodium Related Antibodies

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Description

2'/3'-O-Acetyl-ADP-ribose sodium is an inhibitor of cell division and oocyte maturation. 2'/3'-O-Acetyl-ADP-ribose sodium causes delay or arrest of oocyte maturation and blastomere division in embryos. 2'/3'-O-Acetyl-ADP-ribose sodium is produced by Sir2 family deacetylases during the coupling of histone/protein deacetylation with β-NAD+ cleavage. In neutral or weakly alkaline aqueous solutions, the direct enzymatic product forms of 2'/3'-O-Acetyl-ADP-ribose sodium, namely the 2'-O-acetyl form and the 3'-O-acetyl form, undergo intramolecular lactone exchange reaction and interconvert with each other[1].

IC50 & Target[1]

SIRT2

 

Molecular Weight

645.32

Formula

C17H23N5Na2O15P2
CAS No.
SMILES

NC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](COP(OP(OC[C@@H](O)[C@@H](O)[C@H](C=O)OC(C)=O)(O[Na])=O)(O[Na])=O)O3
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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2'/3'-O-Acetyl-ADP-ribose sodium Related Classifications

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Keywords:

2'/3'-O-Acetyl-ADP-ribose1312013-29-8Sirtuinβ-NAD+NMR spectroscopyDrosophilaAcLys-14 H3 peptideyeastoocyte maturationSir2 family histone/protein deacetylasesembryo blastomere cell divisionhumansHST2Inhibitorinhibitorinhibit

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