Fmoc-Gly-NH-CH2-O-CH2COOH
Based on 1 Customer Validation
Fmoc-Gly-NH-CH2-O-CH2COOH is an ADC linker. Fmoc-Gly-NH-CH2-O-CH2COOH can be used for synthesis of ADCs.
For research use only. We do not sell to patients.
- Purity: 99.13%
- CAS No.: 1599440-08-0
- Formula: C20H20N2O6
- Molecular Weight:384.38
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Description
In Vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1599440-08-0
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Appearance Solid
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Molecular Weight 384.38
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Formula C20H20N2O6
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Color White to off-white
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SMILES
O=C(O)COCNC(CNC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 175 mg/mL (455.28 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6016 mL | 13.0080 mL | 26.0159 mL | 65.0398 mL |
| 5 mM | 0.5203 mL | 2.6016 mL | 5.2032 mL | 13.0080 mL | |
| 10 mM | 0.2602 mL | 1.3008 mL | 2.6016 mL | 6.5040 mL | |
| 15 mM | 0.1734 mL | 0.8672 mL | 1.7344 mL | 4.3360 mL | |
| 20 mM | 0.1301 mL | 0.6504 mL | 1.3008 mL | 3.2520 mL | |
| 25 mM | 0.1041 mL | 0.5203 mL | 1.0406 mL | 2.6016 mL | |
| 30 mM | 0.0867 mL | 0.4336 mL | 0.8672 mL | 2.1680 mL | |
| 40 mM | 0.0650 mL | 0.3252 mL | 0.6504 mL | 1.6260 mL | |
| 50 mM | 0.0520 mL | 0.2602 mL | 0.5203 mL | 1.3008 mL | |
| 60 mM | 0.0434 mL | 0.2168 mL | 0.4336 mL | 1.0840 mL | |
| 80 mM | 0.0325 mL | 0.1626 mL | 0.3252 mL | 0.8130 mL | |
| 100 mM | 0.0260 mL | 0.1301 mL | 0.2602 mL | 0.6504 mL |