Glutathione Peroxidase
Based on 1 Customer Validation
Glutathione Peroxidase (GSH-Px; EC 1.11.1.9) belongs to the peroxidase family and is commonly used in biochemical research. Glutathione Peroxidase can catalyze reduced glutathione (GSH) to form a disulfide bridge with another glutathione molecule, convert it into oxidized glutathione (GSSG), and react with hydrogen peroxide or lipid peroxide reaction, reducing it to H2O. Glutathione Peroxidase is an effective antioxidant against oxidative stress.
For research use only. We do not sell to patients.
- CAS No.: 9013-66-5
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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GPX4 |
Glutathione peroxidase (EC 1.11.1.9) is the general name for a family of multiple isozymes that catalyze the reduction of H2O2 or organic hydroperoxides to water or corresponding alcohols using reduced glutathione (GSH) as an electron donor (H2O2 + 2GSH → GS-SG + 2H2O). In Metazoa, some Glutathione peroxidases have a selenium-dependent glutathione peroxidase activity, with selenocysteine being encoded by an opal TGA codon. In mammalian tissues, there are four major selenium dependent Glutathione peroxidase isozymes: GPx1, GPx2, GPx3, GPx4. GPx1, 2 and 3 act as homotetramers, whereas GPx4 is functional as a monomer[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1.11.1.9
≥300U/mg protein
One unit is defined as the amount of enzyme that will catalyze the oxidation 1.0 μmole of reduced glutathione to oxidized glutathione per min at pH 7.0 at 25°C
Chemical Information
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CAS No. 9013-66-5
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Appearance Liquid
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Color Colorless to light yellow
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SMILES
[Glutathione Peroxidase]
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Synonyms
GSH-Px; EC 1.11.1.9
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (265 KB)
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SDS (418 KB)
- English - EN (418 KB)
- Français - FR (418 KB)
- Deutsch - DE (418 KB)
- Norwegian - NO (418 KB)
- Español - ES (418 KB)
- Swedish - SV (418 KB)
- Italian - IT (418 KB)
- Korean - KR (418 KB)
- Portuguese - PT (418 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Glutathione Peroxidase Related Classifications
HY-P2833 Related Classifications
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