1. Cell Cycle/DNA Damage
  2. G-quadruplex
  3. BMVC2

BMVC2 (Synonyms: o-BMVC)

Cat. No.: HY-135776
Handling Instructions

BMVC2 (o-BMVC) is a bisubstitute carbazole derivative of BMVC. BMVC2 is a G-quadruplex (G4) stabilizer.

For research use only. We do not sell to patients.

BMVC2 Chemical Structure

BMVC2 Chemical Structure

CAS No. : 850559-51-2

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Description

BMVC2 (o-BMVC) is a bisubstitute carbazole derivative of BMVC. BMVC2 is a G-quadruplex (G4) stabilizer[1].

IC50 & Target

G-quadruplex[1]

In Vitro

BMVC2 by monitoring the disappearance of the 291 nm CD signals of d[AG3(T2AG3)3] (HT22) after adding Cu2+ is screened, a longer unfolding time would dictate a better G4 stabilizer. The unfolding curve of HT22 in the presence of BMVC2 can be fitted by using two time constants of 133.7 s (29%) and 2816 s (71%), which are similar to the unfolding parameters of BMVC[1].

Molecular Weight

657.33

Formula

C₂₈H₂₅I₂N₃

CAS No.

850559-51-2

SMILES

C[N+]1=CC=CC=C1/C=C/C2=CC3=C(C=C2)NC4=C3C=C(/C=C/C5=CC=CC=[N+]5C)C=C4.[I-].[I-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

BMVC2o-BMVCBMVC 2BMVC-2G-quadruplexBMVCG4bisubstitutecarbazolederivativeHT22Inhibitorinhibitorinhibit

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