2-O-(2,4,6-Trihydroxyphenyl)-6,6'-bieckol
2-O-(2,4,6-Trihydroxyphenyl)-6,6'-bieckol is a bisphenol compound and a serine protease inhibitor. 2-O-(2,4,6-Trihydroxyphenyl)-6,6'-bieckol exhibits inhibitory activities against α2-macroglobulin, α2-plasmin inhibitor and plasmin, with corresponding IC50 values of 1.9 μg/mL, 0.7 μg/mL and 13 μg/mL.
For research use only. We do not sell to patients.
- CAS No.: 89079-38-9
- Formula: C42H26O21
- Molecular Weight:866.64
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
In Vitro
2-O-(2,4,6-Trihydroxyphenyl)-6,6'-bieckol (compound 4) (20 min at 37 °C) inhibits α2-macroglobulin activity with an IC50 of 1.9 μg/mL[1].
2-O-(2,4,6-Trihydroxyphenyl)-6,6'-bieckol (20 min at 37 °C) inhibits α2-plasmin inhibitor activity with an IC50 of 0.7 μg/mL[1].
2-O-(2,4,6-Trihydroxyphenyl)-6,6'-bieckol inhibits plasmin activity with an IC50 of 13 μg/mL[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 89079-38-9
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Molecular Weight 866.64
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Formula C42H26O21
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SMILES
OC1=CC(OC2=C(C=C(C3=C2OC(C(O)=CC(O)=C4C(C(O)=CC(O)=C5OC6=C(OC7=CC(O)=CC(O)=C7)C(OC8=C(O)C=C(O)C=C8O)=C9)=C5OC6=C9O)=C4O3)O)O)=CC(O)=C1
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)