AChE/BChE-IN-16
AChE/BChE-IN-16 (compound C7) is a potent cholinesterase (ChE) inhibitor with IC50s of 30 nM and 48 nM for human acetylcholinesterase (hAChE) and human butyrylcholinesterase (hBChE), respectively. AChE/BChE-IN-16 exhibits a remarkable capacity to safeguard PC12 cells against H2O2-induced apoptosis and effectively suppresses the production of reactive oxygen species (ROS).
For research use only. We do not sell to patients.
- CAS No.: 3038810-09-9
- Formula: C33H34FN5O2
- Molecular Weight:551.65
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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hAChE 30 nM (IC50) |
hBCHE 48 nM (IC50) |
Chemical Information
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CAS No. 3038810-09-9
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Molecular Weight 551.65
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Formula C33H34FN5O2
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SMILES
O=C(NCCCCCCNC1=C(C=CC(F)=C2)C2=NC3=C1CCCC3)OC4=CC=C(C(N5)=CC6=C5N=CC=C6)C=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)