TOPS
Based on 1 publication(s) in Google Scholar
TOPS is a chromogenic substrate. TOPS undergoes an oxidative coupling reaction with 4-aminoantipyrine in the presence of H2O2 and nanocrystalline cobalt selenide. TOPS is used in studies related to uric acid detection.
For research use only. We do not sell to patients.
- Purity: 99.81%
- CAS No.: 40567-80-4
- Formula: C12H18NNaO3S
- Molecular Weight:279.33
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) TOPS
More
Biological Activity
TOPS (3.2 mM) reacts with 4-AAP in the presence of H2O2 and nanocrystalline cobalt selenide to produce a purple product with a maximum absorbance at 550 nm[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 40567-80-4
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Appearance Solid
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Molecular Weight 279.33
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Formula C12H18NNaO3S
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Color White to off-white
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SMILES
O=S(CCCN(CC)C1=CC=CC(C)=C1)(O[Na])=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
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Redox Biol
USP20 governs tyrosine kinase inhibitors resistance through ferroptosis evasion by targeting GPX4 in cancers. [Abstract]2026 May:92:104086. PMID: 41844497
Solvent & Solubility
DMSO : 100 mg/mL (358.00 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.5800 mL | 17.9000 mL | 35.8000 mL | 89.4999 mL |
| 5 mM | 0.7160 mL | 3.5800 mL | 7.1600 mL | 17.9000 mL | |
| 10 mM | 0.3580 mL | 1.7900 mL | 3.5800 mL | 8.9500 mL | |
| 15 mM | 0.2387 mL | 1.1933 mL | 2.3867 mL | 5.9667 mL | |
| 20 mM | 0.1790 mL | 0.8950 mL | 1.7900 mL | 4.4750 mL | |
| 25 mM | 0.1432 mL | 0.7160 mL | 1.4320 mL | 3.5800 mL | |
| 30 mM | 0.1193 mL | 0.5967 mL | 1.1933 mL | 2.9833 mL | |
| 40 mM | 0.0895 mL | 0.4475 mL | 0.8950 mL | 2.2375 mL | |
| 50 mM | 0.0716 mL | 0.3580 mL | 0.7160 mL | 1.7900 mL | |
| 60 mM | 0.0597 mL | 0.2983 mL | 0.5967 mL | 1.4917 mL | |
| 80 mM | 0.0447 mL | 0.2237 mL | 0.4475 mL | 1.1187 mL | |
| 100 mM | 0.0358 mL | 0.1790 mL | 0.3580 mL | 0.8950 mL |
TOPS Related Classifications
HY-15933 Related Classifications
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