2-O-trans-p-Coumaroylalphitolic acid
2-O-trans-p-Coumaroylalphitolic acid (Zj7) is a triterpene which can be extracted from jujube plants. 2-O-trans-P-Coumaroyl alphitolic acid is a selective modulator of glucocorticoid receptor (GR). 2-O-trans-P-coumaroyl alphitolic acid can be used in the study of obesity.
For research use only. We do not sell to patients.
- CAS No.: 67911-63-1
- Formula: C39H54O6
- Molecular Weight:618.84
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
2 μM
Compound: 29
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Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
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[PMID: 27617953] |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:DIO mice[1]
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Dosage:50 mg/kg
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Administration:i.p. every day for 2 weeks
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Result:Enhanced insulin sensitivity.
Repressed. the expression of Agrp, Npy and Cdkn1a in the ARC
Chemical Information
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CAS No. 67911-63-1
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Molecular Weight 618.84
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Formula C39H54O6
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SMILES
[H][C@]12CC[C@@]3([C@]4([C@@H](CC[C@@]4(CC[C@]3([C@@]1(CC[C@]5(C(C)([C@H]([C@@H](C[C@]25C)OC(/C=C/C6=CC=C(C=C6)O)=O)O)C)[H])C)C)C(O)=O)C(C)=C)[H])[H]
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Structure Classification
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)